Výsledky vyhledávání - "Sridevi Duggirala"

Phytochemicals as Inhibitors of Bacterial Cell Division Protein FtsZ: Coumarins Are Promising Candidates

Autor: Rakesh P. Nankar, Selvakumar Rajendran, Sridevi Duggirala, Mukesh Doble

Publikováno v: Applied Biochemistry and Biotechnology. 174:283-296

Naturally occurring phytochemicals with reported antibacterial activity were screened for their ability to inhibit the bacterial cell division protein Escherichia coli FtsZ. Among the representative compounds, coumarins inhibit the GTPase and polymer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70b1773e15d73a4694a30f0b1f6d0b2
https://doi.org/10.1007/s12010-014-1056-2

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FtsZ inhibition and redox modulation with one chemical scaffold: Potential use of dihydroquinolines against mycobacteria

Autor: Sridevi Duggirala, V. Senu Adeeba, Muraleedharan K. Manheri, Mukesh Doble, John Victor Napoleon, Rakesh P. Nankar

Publikováno v: European journal of medicinal chemistry. 123

The dual effect of FtsZ inhibition and oxidative stress by a group of 1,2-dihydroquinolines that culminate in bactericidal effect on mycobacterium strains is demonstrated. They inhibited the non-pathogenic Mycobacterium smegmatis mc2 155 with MIC as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa17be8683db2c604295892372b68d1
https://pubmed.ncbi.nlm.nih.gov/27517804

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T-cell recognition of iron-regulated culture filtrate proteins of Mycobacterium tuberculosis in tuberculosis patients and endemic normal controls

Autor: K Venu, Manjula Sritharan, K Subhakar, Sridevi Duggirala

Publikováno v: Indian Journal of Medical Microbiology, Vol 30, Iss 3, Pp 323-331 (2012)

Background: Culture filtrate proteins (CFPs) of Mycobacterium tuberculosis are potential vaccine candidates. Objective: The aim was to study the influence of iron levels on CFPs and assess the immuno-protective potential of defined antigenic fraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289fbf7713d92fef387285410db65105
http://www.ijmm.org/article.asp?issn=0255-0857

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Identification and Characterization of a Major Cell Wall-Associated Iron-Regulated Envelope Protein (Irep-28) in Mycobacterium tuberculosis

Autor: Manjula Sritharan, Friedrich Altmann, Veena C. Yeruva, V. Lakshmi, Daniel Kolarich, Sridevi Duggirala

Publikováno v: Clinical and Vaccine Immunology. 13:1137-1142

Iron limitation and the expression of mycobactin and carboxymycobactin by Mycobacterium tuberculosis are known. Here, we report how iron regulated the coordinate expression of these two siderophores and a 28-kDa cell wall-associated iron-regulated pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2878981598db2ed7173fa293de90bee1
https://doi.org/10.1128/cvi.00125-06

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Serum Levels of Neopterin during Antimicrobial Treatment for Mycobacterium ulcerans Infection

Autor: Sridevi Duggirala, Till F. Omansen, Tjip S. van der Werf, Willemien A. Nienhuis, Ymkje Stienstra, Janine de Zeeuw, Wilson Tuah, K. Mohammed Abass

Publikováno v: The American Society of Tropical Medicine and Hygiene, 89(3), 498-500

Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e3621515cc8436a50e85c950ed830e
https://europepmc.org/articles/PMC3771288/

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Immunology in tuberculosis: challenges in monitoring of disease activity and identifying correlates of protection

Autor: Richard van Altena, Sridevi Duggirala, Tjip S. van der Werf, Matthias I. Gröschel

Publikováno v: Current pharmaceutical design. 17(27)

Humans have always lived with tubercle bacilli. Host susceptibility – both inherited and acquired – determines whether an individual infected with Mycobacterium tuberculosis will eventually fall ill and develop tuberculosis (TB). After infection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04757c132b4592d3047f63ee12cffdaf
https://pubmed.ncbi.nlm.nih.gov/21834760

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Iron enhances the susceptibility of pathogenic mycobacteria to isoniazid, an antitubercular drug

Autor: Veena C. Yeruva, Manjula Sritharan, Sridevi Duggirala, Sivagamisundaram C. Sivasailappan

Publikováno v: World Journal of Microbiology and Biotechnology. 22

The catalase-peroxidase KatG of Mycobacterium tuberculosis plays a central role in the mechanism of action of the anti-tubercular drug isoniazid (INH). Like other bacterial catalases, mycobacterial catalase-peroxidases are dual active enzymes with bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b854e02ad368ae6fe1445bb0c9a5fb7d
https://doi.org/10.1007/s11274-006-9183-8

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