Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sri Rahavi Boovarahan"'
Autor:
Sri Rahavi Boovarahan, Nemat Ali, Abdullah F. AlAsmari, Alaa Alnoor Alameen, Rehan Khan, Gino A. Kurian
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Most pre-clinical studies in cardiac ischemia-reperfusion injury (I/R) are carried out in young or old animals, which does not cater to the adult age in humans who encounter I/R. Not many studies in the literature are available that emphasize the sen
Externí odkaz:
https://doaj.org/article/2bc0732eef73438eaa1a31d823260631
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Ischemia reperfusion (I/R) injury is one of the main clinical challenges for cardiac surgeons. No effective strategies or therapy targeting the molecular and cellular mechanisms to reduce I/R exists to date, despite altered gene expression and cellul
Externí odkaz:
https://doaj.org/article/57c01e9a06174b848853bc3b9bd2c8dc
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 10, Iss 7, Pp 333-340 (2020)
Objective: To compare the anti-proliferative effect of sodium thiosulfate on human colorectal cancer cells (HT-29) and normal small intestine cells (IEC6). Methods: Cells (HT-29 and IEC6) were treated with different concentrations of sodium thiosulfa
Externí odkaz:
https://doaj.org/article/277a907acfb74206af3535c4cf0e4e2c
Autor:
Sri Rahavi Boovarahan, David Raj Chellappan, Nemat Ali, Abdullah F. AlAsmari, Mohammad Waseem, Abdullah Saad Alabdulrahim, Ziyad Ali Alzahrani, Gino A. Kurian
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3065 (2022)
A recent study has shown that DNA hypermethylation can promote ischemia reperfusion (I/R) injury by regulating the mitochondrial function. Diabetes mellitus (DM) is reported to induce DNA hypermethylation, but whether this prior DNA methylation in DM
Externí odkaz:
https://doaj.org/article/14164cdb47ff4e5f8fc6290e7ceded78
Publikováno v:
Phytomedicine Plus, Vol 1, Iss 3, Pp 100094- (2021)
Background: The rat myocardium consists of different cell types of which cardiomyocytes account for 70% of the total surface area. The extent of ischemia reoxygenation injury (IRI) experienced by each cell type of the heart varies. Fisetin, a natural
Externí odkaz:
https://doaj.org/article/2a93b226c1314ceabe3c55b96409dcf1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Ischemia-reperfusion (I/R) injury is an unavoidable injury that occurs during revascularization procedures. In the previous study, we reported that fisetin is a natural flavonoid that attenuates I/R injury by suppressing mitochondrial oxidative stres
Externí odkaz:
https://doaj.org/article/88d7b84ab6734432b6f8f42e0449af1b
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 14, Iss 2 (2019)
Hydrogen sulfide has been shown to protect myocardium against ischemia-reperfusion injury by preserving interfibrillar mitochondria functional activi-ties than subsarcolemmal mitochondria. In this study, the role of the KATP channel in modulating the
Externí odkaz:
https://doaj.org/article/c8da412c065b45dba5a735fa6effe215
Publikováno v:
American Journal of Chemistry and Pharmacy. 2:8-20
5-Azacytidine is a hypomethylating agent that has for long been used in cancer therapy due to its ability to inhibit the protein DNA methyltransferase responsible for hyper-methylating DNA strands. Recently, studies involving in vitro, ex vivo, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a987b775409af31d1b3eaff761e4cdb5
https://doi.org/10.54536/ajcp.v2i1.1169
https://doi.org/10.54536/ajcp.v2i1.1169
Autor:
Kurian, Sri Rahavi Boovarahan, Suresh Babu Kale, Priyanka N. Prem, Sriram Ravindran, Akshayakeerthi Arthanarisami, Jeyashri Rengaraju, Nemat Ali, Senthilkumar Ramalingam, Mohamed Mohany, Abdullah F. AlAsmari, Salim S. Al-Rejaie, Mohammad Waseem, Gino A.
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 12; Pages: 4146
Global DNA hypermethylation and mitochondrial dysfunction are reported to be associated with the development of mild cognitive decline (MCI). The present study aims to generate preliminary data that connect the above association with post-surgical co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fb8d8fb41647b554d2abd515212a2743
Publikováno v:
Cell Biochemistry and Biophysics. 80:123-137
According to our previous study, fisetin (3,3',4',7-tetrahydroxyflavone), a bioactive phytochemical (flavonol), reportedly showed cardioprotection against ischemia-reperfusion injury (IRI) by reducing oxidative stress and inhibiting glycogen synthase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ac9fe4b73e462ec0210047f04ea347
https://doi.org/10.1007/s12013-021-01026-4
https://doi.org/10.1007/s12013-021-01026-4