Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sri Gowtham Thakku"'
Autor:
Sri Gowtham Thakku, Jackson Lirette, Kanagavel Murugesan, Julie Chen, Grant Theron, Niaz Banaei, Paul C. Blainey, James Gomez, Sharon Y. Wong, Deborah T. Hung
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
In this work, the authors developed a multiplexed, minimally invasive, CRISPR-Cas13-based approach to detect Mycobacterium tuberculosis cell-free DNA in the plasma of active pulmonary tuberculosis patients.
Externí odkaz:
https://doaj.org/article/bbeaeafe49934ce4acd3e1fecb9b7f87
Autor:
Nicole L. Welch, Meilin Zhu, Catherine Hua, Juliane Weller, Marzieh Ezzaty Mirhashemi, Tien G. Nguyen, Sreekar Mantena, Matthew R. Bauer, Bennett M. Shaw, Cheri M. Ackerman, Sri Gowtham Thakku, Megan W. Tse, Jared Kehe, Marie-Martine Uwera, Jacqueline S. Eversley, Derek A. Bielwaski, Graham McGrath, Joseph Braidt, Jeremy Johnson, Felecia Cerrato, Gage K. Moreno, Lydia A. Krasilnikova, Brittany A. Petros, Gabrielle L. Gionet, Ewa King, Richard C. Huard, Samantha K. Jalbert, Michael L. Cleary, Nicholas A. Fitzgerald, Stacey B. Gabriel, Glen R. Gallagher, Sandra C. Smole, Lawrence C. Madoff, Catherine M. Brown, Matthew W. Keller, Malania M. Wilson, Marie K. Kirby, John R. Barnes, Daniel J. Park, Katherine J. Siddle, Christian T. Happi, Deborah T. Hung, Michael Springer, Bronwyn L. MacInnis, Jacob E. Lemieux, Eric Rosenberg, John A. Branda, Paul C. Blainey, Pardis C. Sabeti, Cameron Myhrvold
Publikováno v:
Nature Medicine. 28:1083-1094
The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear need for high-throughput, multiplexed and sensitive assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses and their em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3ea8d1b520b0550568fd82b8c53484
https://doi.org/10.1038/s41591-022-01734-1
https://doi.org/10.1038/s41591-022-01734-1
Autor:
Deborah T. Hung, Jonathan Livny, Cameron Myhrvold, Sri Gowtham Thakku, Cheri M. Ackerman, Paul C. Blainey, Pardis C. Sabeti, Peijun Ma, Giselle Isabella Gomez, Roby P. Bhattacharyya
Publikováno v:
PNAS nexus. 1(1)
Rapid and accurate diagnosis of infections is fundamental to individual patient care and public health management. Nucleic acid detection methods are critical to this effort, but are limited either in the breadth of pathogens targeted or by the exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b62ad23d40570b286250351dc5350a
https://pubmed.ncbi.nlm.nih.gov/35450424
https://pubmed.ncbi.nlm.nih.gov/35450424
Autor:
Anthony Kulesa, Jared Kehe, Sri Gowtham Thakku, Pardis C. Sabeti, Tien G. Nguyen, Chloe K. Boehm, Hayden C. Metsky, Cheri M. Ackerman, Tinna Solveig F. Kosoko-Thoroddsen, David Yang, Vivien G. Dugan, Cameron Myhrvold, Paul C. Blainey, Catherine A. Freije, John R. Barnes, Deborah T. Hung, Simon Ye, Amber Carter
Publikováno v:
Nature
The great majority of globally circulating pathogens go undetected, undermining patient care and hindering outbreak preparedness and response. To enable routine surveillance and comprehensive diagnostic applications, there is a need for detection tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97d83d0787eb7b0adaa1e6c5e4b5fb1
Publikováno v:
ACS Infectious Diseases. 4:1278-1282
Nucleic acid detection is an important method for pathogen identification but can be expensive, have variable sensitivity and specificity, and require substantial infrastructure. Two new methods capitalize on unexpected in vitro properties of cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36376e75a5c9e72265bbdbcb817db1a5
https://doi.org/10.1021/acsinfecdis.8b00170
https://doi.org/10.1021/acsinfecdis.8b00170
Autor:
Chui Ming Gemmy Cheung, Ching-Yu Cheng, Sri Gowtham Thakku, Ranjana Mathur, Doric Wong, Ian Yeo, Edmund Wong, Preeti Gupta, Daniel Shu Wei Ting, Tien Yin Wong
Publikováno v:
Retina. 37:2269-2280
To characterize and compare morphologic and vascular features of the choroid in patients with typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) and to determine if PCV subtypes can be identified based on these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fede8c8be7e9ff069f2ec0cd21d3ed8
https://doi.org/10.1097/iae.0000000000001481
https://doi.org/10.1097/iae.0000000000001481
Autor:
Anthony Ortiz, Jared Kehe, Seppe Kuehn, Paul C. Blainey, Sri Gowtham Thakku, Anthony Kulesa, Cheri M. Ackerman, Daniel Sellers, Jonathan Friedman, Jeff Gore
Microbial communities have numerous potential applications in biotechnology, agriculture, and medicine. Nevertheless, the limited accuracy with which we can predict interspecies interactions and environmental dependencies hinders efforts to rationall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89e644e112f7d35946ed5c78a331496
https://europepmc.org/articles/PMC6600964/
https://europepmc.org/articles/PMC6600964/
Autor:
Mani Baskaran, Sri Gowtham Thakku, Nicholas G. Strouthidis, Liang Zhang, Tin Aung, Michael J A Girard, James C.H. Goh, Meghna R. Beotra
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 16:871-887
We aimed to verify a custom virtual fields method (VFM) to estimate the patient-specific biomechanical properties of human optic nerve head (ONH) tissues, given their full-field deformations induced by intraocular pressure (IOP). To verify the accura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61e9682b10551f6bcf7de3c7581fec3
https://doi.org/10.1007/s10237-016-0858-2
https://doi.org/10.1007/s10237-016-0858-2
Autor:
Marcus Chiang Lee Tan, Ching-Yu Cheng, Tin A. Tun, Sri Gowtham Thakku, Jacqueline Chua, Tin Aung, Michael J A Girard, Tien Yin Wong, Joanne Hui Min Quah, Monisha E. Nongpiur
Publikováno v:
Ophthalmology. 123:2077-2084
Purpose To determine the association of iris surface features with iris volume change after physiologic pupil dilation in adults. Design Cross-sectional observational study. Participants Chinese adults aged ≥ 50 years without ocular diseases. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751f109d16b2e880a91b33cd48bb4dde
https://doi.org/10.1016/j.ophtha.2016.06.034
https://doi.org/10.1016/j.ophtha.2016.06.034
Autor:
Joanne Hui Min Quah, Tin Aung, Tin A. Tun, Elizabeth Sidhartha, Jacqueline Chua, Sri Gowtham Thakku, Yuan Shi, Ching-Yu Cheng, William Shei, Marcus Chiang Lee Tan
Publikováno v:
British Journal of Ophthalmology. 100:1682-1685
To characterise the association of iris surface features (crypts, furrows and colour) with iris volume and curvature assessed by swept-source optical coherence tomography (SSOCT) in Asian eyes.Iris crypts (by number and size) and furrows (by number a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcc2e63399da544131c86905007a214
https://doi.org/10.1136/bjophthalmol-2015-308256
https://doi.org/10.1136/bjophthalmol-2015-308256