Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sreevidhya Krishnaji"'
Autor:
Dayami Lopez, Quantil M. Melendez, Catherine J. Wooten, Sreevidhya Krishnaji, David R. Kirchner, Kevin J. Knagge
Publikováno v:
International journal of biomedical investigation
High levels of cholesterol, especially as low-density lipoprotein (LDL), are a well-known risk factor for atherosclerotic-related diseases. The key atherogenic property of LDL is its ability to form atherosclerotic plaque. Proprotein convertase subti
Autor:
Randolph V. Lewis, Michael B. Hinman, Paula F. Oliveira, Sreevidhya Krishnaji, Thomas I. Harris, Gargi Bhattacharyya, Dong Chen, Amir Ghazitabatabaei, Brianne E. Bell, Justin A. Jones
Publikováno v:
Protein expression and purification. 183
Spider silk, which has remarkable mechanical properties, is a natural protein fiber produced by spiders. Spiders cannot be farmed because of their cannibalistic and territorial nature. Hence, large amounts of spider silk cannot be produced from spide
Publikováno v:
Archives of Biochemistry and Biophysics. :39-53
Heart disease ends the life of more people than any other disease in the United States. High levels of low density lipoprotein (LDL)-cholesterol cause heart diseases by increasing the formation of atherosclerotic plaques. Proprotein convertase subtil
Publikováno v:
Polymer. 117:107-116
The self-assembly morphology, crystallization kinetics and thermal degradation process of biopolymers with well-defined amino acid sequences was investigated, using a specially created family of silk-based block copolymers patterned after Nephila Cla
Publikováno v:
International journal of biomedical investigation
Proprotein convertase subtilisin-kexin 9 (PCSK9) appears to be involved in multiple processes. A ProtoArray Human Protein Microarray was used to identify proteins interacting with biotinylated PCSK9. Fifteen novel proteins interacting with PCSK9 were
Autor:
Akhilesh Kumar, Ranjeet Singh Mahla, Helena J. Tutill, Bharathwaj Sathyamoorthy, Amit K. Pandey, Judith Breuer, Sreevidhya Krishnaji, Himanshu Kumar, Mahdad Noursadeghi
Publikováno v:
Tuberculosis. 126:102046
RNASeq analysis of PBMCs from treatment naïve TB patients and healthy controls revealed that M. tuberculosis (Mtb) infection dysregulates several metabolic pathways and upregulates BNIP3L/NIX receptor mediated mitophagy. Analysis of publicly availab
Publikováno v:
Macromolecules. 47:8098-8106
We have developed a methodology using advanced thermal analysis to characterize the role of water in a specially synthesized family of recombinant spider silk-like block copolymers. These proteins were inspired by the genetic sequences found in the d
Publikováno v:
Macromolecules. 47:8107-8114
Fibrous protein secondary structural transitions are affected by bound water. A family of specially designed recombinant spider silk-like block copolymers with a gradient of block length, hydrophobilicity, and degree of crystallinity was biosynthesiz
Publikováno v:
Macromolecular Chemistry and Physics. 215:1230-1238
Autor:
Sreevidhya Krishnaji, David L. Kaplan
Publikováno v:
Macromolecular Bioscience. 13:256-264
Heavy metals constitute a source of environmental pollution. Here, novel functional hybrid biomaterials for specific interactions with heavy metals are designed by bioengineering consensus sequence repeats from spider silk of Nephila clavipes with re