Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sreevalsam Gopinath"'
Autor:
Danielle B. Ulanet, Kevin M. Marks, Josh Murtie, Scott A. Biller, Jonathan Hurov, Georg Lenz, Lenny Dang, Nelamangala Nagaraja, Zhihua Sui, Sreevalsam Gopinath, Thomas Antony, Sunil K. Panigrahi, K. Satish Reddy, Hosahalli Subramanya, Siva Sanjeeva Rao, Kavitha Nellore, Mark Fletcher, Sebastian Hayes, Alan Mann, Tabea Erdmann, Zi-Peng Fan, Charles Locuson, Sebastien Ronseaux, Lei Jin, Anil K. Padyana, Erin Artin, Mya Steadman, Sung Choe, Rohini Narayanaswamy, Kevin Truskowski, John Coco, Victor Chubukov, Gabrielle McDonald
GO analysis of proteins with at least a 1.5-fold increase in expression in the presence of AG-636 compared to DMSO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b4ca858542c027e4592c9d144d2e2b
https://doi.org/10.1158/1535-7163.22520980.v1
https://doi.org/10.1158/1535-7163.22520980.v1
Autor:
Danielle B. Ulanet, Kevin M. Marks, Josh Murtie, Scott A. Biller, Jonathan Hurov, Georg Lenz, Lenny Dang, Nelamangala Nagaraja, Zhihua Sui, Sreevalsam Gopinath, Thomas Antony, Sunil K. Panigrahi, K. Satish Reddy, Hosahalli Subramanya, Siva Sanjeeva Rao, Kavitha Nellore, Mark Fletcher, Sebastian Hayes, Alan Mann, Tabea Erdmann, Zi-Peng Fan, Charles Locuson, Sebastien Ronseaux, Lei Jin, Anil K. Padyana, Erin Artin, Mya Steadman, Sung Choe, Rohini Narayanaswamy, Kevin Truskowski, John Coco, Victor Chubukov, Gabrielle McDonald
Supplementary methods, references and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0375725bf558a85632625bf90c45d1f
https://doi.org/10.1158/1535-7163.22520971
https://doi.org/10.1158/1535-7163.22520971
Autor:
Danielle B. Ulanet, Kevin M. Marks, Josh Murtie, Scott A. Biller, Jonathan Hurov, Georg Lenz, Lenny Dang, Nelamangala Nagaraja, Zhihua Sui, Sreevalsam Gopinath, Thomas Antony, Sunil K. Panigrahi, K. Satish Reddy, Hosahalli Subramanya, Siva Sanjeeva Rao, Kavitha Nellore, Mark Fletcher, Sebastian Hayes, Alan Mann, Tabea Erdmann, Zi-Peng Fan, Charles Locuson, Sebastien Ronseaux, Lei Jin, Anil K. Padyana, Erin Artin, Mya Steadman, Sung Choe, Rohini Narayanaswamy, Kevin Truskowski, John Coco, Victor Chubukov, Gabrielle McDonald
Genome-wide CRISPR depletion screen data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e102e0de1f8fbcbd5c71e914dabb75
https://doi.org/10.1158/1535-7163.22520983
https://doi.org/10.1158/1535-7163.22520983
Autor:
Danielle B. Ulanet, Kevin M. Marks, Josh Murtie, Scott A. Biller, Jonathan Hurov, Georg Lenz, Lenny Dang, Nelamangala Nagaraja, Zhihua Sui, Sreevalsam Gopinath, Thomas Antony, Sunil K. Panigrahi, K. Satish Reddy, Hosahalli Subramanya, Siva Sanjeeva Rao, Kavitha Nellore, Mark Fletcher, Sebastian Hayes, Alan Mann, Tabea Erdmann, Zi-Peng Fan, Charles Locuson, Sebastien Ronseaux, Lei Jin, Anil K. Padyana, Erin Artin, Mya Steadman, Sung Choe, Rohini Narayanaswamy, Kevin Truskowski, John Coco, Victor Chubukov, Gabrielle McDonald
Agents targeting metabolic pathways form the backbone of standard oncology treatments, though a better understanding of differential metabolic dependencies could instruct more rationale-based therapeutic approaches. We performed a chemical biology sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c2082a01fe43de83bde9d3812f1570
https://doi.org/10.1158/1535-7163.c.6542857
https://doi.org/10.1158/1535-7163.c.6542857
Autor:
Danielle B. Ulanet, Kevin M. Marks, Josh Murtie, Scott A. Biller, Jonathan Hurov, Georg Lenz, Lenny Dang, Nelamangala Nagaraja, Zhihua Sui, Sreevalsam Gopinath, Thomas Antony, Sunil K. Panigrahi, K. Satish Reddy, Hosahalli Subramanya, Siva Sanjeeva Rao, Kavitha Nellore, Mark Fletcher, Sebastian Hayes, Alan Mann, Tabea Erdmann, Zi-Peng Fan, Charles Locuson, Sebastien Ronseaux, Lei Jin, Anil K. Padyana, Erin Artin, Mya Steadman, Sung Choe, Rohini Narayanaswamy, Kevin Truskowski, John Coco, Victor Chubukov, Gabrielle McDonald
X-ray data collection and refinement statistics for DHODH•FMN•ORO•AG-636
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6cfd0e10eb665263e81521e6af3920
https://doi.org/10.1158/1535-7163.22520974.v1
https://doi.org/10.1158/1535-7163.22520974.v1
Autor:
Ramulu Poddutoori, Kimberly Aardalen, Kiran Aithal, Sanjeev Surendranath Barahagar, Charamanna Belliappa, Mark Bock, Shekar Chelur, Andrea Gerken, Sreevalsam Gopinath, Bjoern Gruenenfelder, Michael Kiffe, Maithreyi Krishnaswami, John Langowski, Sudharshan Madapa, Kishore Narayanan, Chetan Pandit, Sunil Kumar Panigrahi, Mark Perrone, Ravi Kumar Potakamuri, Murali Ramachandra, Anuradha Ramanathan, Rita Ramos, Emine Sager, Susanta Samajdar, Hosahalli S. Subramanya, Devaraja Seethappa Thimmasandra, Eleni Venetsanakos, Henrik Möbitz
Publikováno v:
Journal of Medicinal Chemistry. 65:4350-4366
Mutations in MEK1/2 have been described as a resistance mechanism to BRAF/MEK inhibitor treatment. We report the discovery of a novel ATP-competitive MEK1/2 inhibitor with efficacy in wildtype (WT) and mutant MEK12 models. Starting from a HTS hit, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df3980bf0fc9797eb2d0401e08b1d0f
https://doi.org/10.1021/acs.jmedchem.1c02192
https://doi.org/10.1021/acs.jmedchem.1c02192
Publikováno v:
Materials Today: Proceedings. 45:6638-6644
Diesel engines are commonly known for its high-power output and high performance. However, the rise in energy consumption, the gradual depletion of petroleum fuels and compliance with strict emission regulations are of great interest to researchers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3e99680046307fc2bebb98b04a3a9b
https://doi.org/10.1016/j.matpr.2020.11.865
https://doi.org/10.1016/j.matpr.2020.11.865
Autor:
K. Satish Reddy, Scott A. Biller, Kavitha Nellore, Siva Sanjeeva Rao, Anil K. Padyana, Georg Lenz, Thomas Antony, Charles Locuson, Jonathan Hurov, Mya Steadman, Tabea Erdmann, Mark Fletcher, Zi Peng Fan, Kevin Truskowski, Sreevalsam Gopinath, Alan Mann, Danielle Ulanet, Rohini Narayanaswamy, Sebastien Ronseaux, Gabrielle McDonald, Sung Choe, Zhihua Sui, John Coco, Lenny Dang, Kevin Marks, Victor Chubukov, Erin Artin, Sebastian Hayes, Josh Murtie, Lei Jin, Nelamangala Nagaraja, Hosahalli Subramanya, Sunil Kumar Panigrahi
Publikováno v:
Molecular cancer therapeutics. 19(12)
Agents targeting metabolic pathways form the backbone of standard oncology treatments, though a better understanding of differential metabolic dependencies could instruct more rationale-based therapeutic approaches. We performed a chemical biology sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4f845cc62e9703a40911be67f90bd8
https://pubmed.ncbi.nlm.nih.gov/33082276
https://pubmed.ncbi.nlm.nih.gov/33082276
Autor:
R. Nishanth, Sreevalsam Gopinath, Priya R Krishnan, R. Sheeja, K.G. Ashok, Chidambaranathan Bibin
Publikováno v:
IOP Conference Series: Materials Science and Engineering. 906:012023
In recent days, the growth of digital data has been increased explosively due to data-intensive applications like healthcare, education and electronic commerce. Due to the huge volume of data created and the utilization of data in emerging applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37af83e588c70cadb6bd907ba6c671ed
https://doi.org/10.1088/1757-899x/906/1/012023
https://doi.org/10.1088/1757-899x/906/1/012023
Autor:
Rajeev Goswami, Subhendu Mukherjee, Gerd Wohlfahrt, Jwala Nagaraj, Krishnaprasad Subbarao, Chakshusmathi Ghadiyaram, Narasimha Rao Krishnamurthy, Leena Khare Satyam, Sreevalsam Gopinath, Hosahalli Subramanya, Murali Ramachandra
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:616-620
Matriptase is a cell-surface trypsin-like serine protease of epithelial origin, which cleaves and activates proteins including hepatocyte growth factor/scatter factor and proteases such as uPA, which are involved in the progression of various cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af98eb705b94b9713c1a02f4738d18fb
https://doi.org/10.1016/j.bmcl.2014.12.008
https://doi.org/10.1016/j.bmcl.2014.12.008