Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Sreerupa Ray"'
1
Yeast-based screening of cancer mutations in the DNA damage response protein Mre11 demonstrates importance of conserved capping domain residues
Autor: Sreerupa Ray, Caitlin Harris, Erin K. Shanle, Jessica Savas
Publikováno v: Molecular biology reports. 48(5)
DNA damage response (DDR) pathways are initiated to prevent mutations from being passed on in the event of DNA damage. Mutations in DDR proteins can contribute to the development and maintenance of cancer cells, but many mutations observed in human t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cd5c8112d75b9419b516103c3880c2
https://pubmed.ncbi.nlm.nih.gov/34075539
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2
DNA polymerase beta participates in DNA End-joining
Autor: Sreerupa Ray, Joann B. Sweasy, Michelle DeVeaux, Daniel Zelterman, Gregory A. Breuer, Ranjit S. Bindra
Publikováno v: Nucleic Acids Research
DNA double strand breaks (DSBs) are one of the most deleterious lesions and if left unrepaired, they lead to cell death, genomic instability and carcinogenesis. Cells combat DSBs by two pathways: homologous recombination (HR) and non-homologous end-j
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263d9d32b840e1cdd5e460b4ad5e765a
https://doi.org/10.1093/nar/gkx1147
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9
Interaction of Saccharomyces cerevisiae HMO2 Domains with Distorted DNA
Autor: Anne Grove, Sreerupa Ray
Publikováno v: Biochemistry. 51:1825-1835
The Saccharomyces cerevisiae high mobility group protein HMO2 is a component of the chromatin remodeling complex INO80. In this capacity, it has been shown to direct INO80 to DNA double-strand breaks, thereby contributing to double-strand break repai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09662537aa207940953bf271027147ce
https://doi.org/10.1021/bi201700h
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10
The yeast high mobility group protein HMO2, a subunit of the chromatin-remodeling complex INO80, binds DNA ends
Autor: Sreerupa Ray, Anne Grove
Publikováno v: Nucleic Acids Research
DNA damage is a common hazard that all cells have to combat. Saccharomyces cerevisiae HMO2 is a high mobility group protein (HMGB) that is a component of the chromatin-remodeling complex INO80, which is involved in double strand break (DSB) repair. W
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b95342d013fe37953c8d6367ed65cff
https://doi.org/10.1093/nar/gkp695
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