Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sreerupa Challa"'
Autor:
Thomas J. Hayman, Marta Baro, Tyler MacNeil, Chatchai Phoomak, Thazin Nwe Aung, Wei Cui, Kevin Leach, Radhakrishnan Iyer, Sreerupa Challa, Teresa Sandoval-Schaefer, Barbara A. Burtness, David L. Rimm, Joseph N. Contessa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The endoplasmic reticulum-localized adaptor STING regulates the innate immune response through its ability to sense DNA damage. Here the authors reveal that STING functions as a regulator of cellular ROS homeostasis and tumor cell susceptibility to r
Externí odkaz:
https://doaj.org/article/7f9f99967a354a5b93d3fe5db608fc2d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/74a59eff2bcf46339d1914d51aeab207
Autor:
Arshad Khan, Vipul K. Singh, Abhishek Mishra, Emily Soudani, Pearl Bakhru, Christopher R. Singh, Dekai Zhang, David H. Canaday, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Sreerupa Challa, Radhakrishnan P. Iyer, Chinnaswamy Jagannath
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) kills about 1.5 million people each year and the widely used Bacille Calmette-Guérin (BCG) vaccine provides a partial protection against TB in children and adults. Because BCG vaccine evad
Externí odkaz:
https://doaj.org/article/9b24ca6f73184c76b1c13fc31dc71761
Publikováno v:
Journal of Nucleic Acids, Vol 2014 (2014)
Infection with Shiga toxin- (Stx-) producing E. coli causes life threatening hemolytic uremic syndrome (HUS), a leading cause of acute renal failure in children. Of the two antigenically distinct toxins, Stx1 and Stx2, Stx2 is more firmly linked with
Externí odkaz:
https://doaj.org/article/d9e0787b9b894dcdb727d46beec1aa8c
Publikováno v:
Advances in Virology, Vol 2011 (2011)
Peptides corresponding to the foot-and-mouth disease virus VP1 G-H loop are capable of inducing neutralizing antibodies in some species but are considered relatively poor immunogens, especially at mucosal surfaces. However, intranasal administration
Externí odkaz:
https://doaj.org/article/7cfac6e7ae52459c82c9b0b1c59552e9
Autor:
Wei Cui, David L. Rimm, Kevin Leach, Thazin Nwe Aung, Radhakrishnan P. Iyer, Sreerupa Challa, Barbara Burtness, Thomas J. Hayman, Chatchai Phoomak, Tyler MacNeil, Joseph N. Contessa, Marta Baro, Teresa Sandoval-Schaefer
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Resistance to DNA-damaging agents is a significant cause of treatment failure and poor outcomes in oncology. To identify unrecognized regulators of cell survival we performed a whole-genome CRISPR-Cas9 screen using treatment with ionizing radiation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742835bcd26216b89b828bb921aa7025
https://doi.org/10.1038/s41467-021-22572-8
https://doi.org/10.1038/s41467-021-22572-8
Autor:
Sreerupa Challa, Chinnaswamy Jagannath, Christopher R. Singh, Dekai Zhang, Vipul K. Singh, David H. Canaday, Radhakrishnan P. Iyer, Pearl Bakhru, Seetharamaiyer Padmanabhan, Emily Soudani, Abhishek Mishra, Anjaneyulu Sheri, Arshad Khan
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) kills about 1.5 million people each year and the widely used Bacille Calmette-Guérin (BCG) vaccine provides a partial protection against TB in children and adults. Because BCG vaccine evad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fee1a59b58ac5c20928eed786f7b4b
http://europepmc.org/articles/PMC7751440
http://europepmc.org/articles/PMC7751440
Autor:
Lingyun Rui, Jing Xu, Yao-Te Hsieh, Li Yue-Sheng, Jonathan Carnino, Sreerupa Challa, Andrea Umana
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundHigh-dose Interleukin-2 is the earliest FDA-approved immunotherapy for metastatic melanoma and renal cell carcinoma. Unfortunately, its application is limited due to its short half-life and severe toxicity at the therapeutic dose. To limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f02049e5b38741b19cf5f872374327d
https://doi.org/10.1136/jitc-2021-sitc2021.858
https://doi.org/10.1136/jitc-2021-sitc2021.858
Autor:
Kim Lam Chiok, Niraj Shil, Sreerupa Challa, Leena Suppiah, Geeta Meher, Seetharamaiyer Padmanabhan, Lakshmi Bhagat, Diane Schmidt, Kyle Korolowicz, Manasa Suresh, Santanu Bose, Brent Korba, Stephan Menne, Nezam Afdhal, Radhakrishnan Iyer
Publikováno v:
Journal of Hepatology. 73:S839-S840
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85131242e9c50897e0ed05a5be4015f8
https://doi.org/10.1016/s0168-8278(20)32121-8
https://doi.org/10.1016/s0168-8278(20)32121-8
Autor:
Vishal Nair, Dillon Cleary, Diane Schmidt, Leena Suppiah, Sreerupa Challa, Kris Iyer, Shenghua Zhou
Publikováno v:
Cancer Immunology Research. 8:B88-B88
Background: Agonists of the Stimulator of Interferon Genes (STING) pathway have great potential in cancer immunotherapy. Activation of STING in tumor cells and/or antigen-presenting cells (APCs) can induce type I Interferon production leading to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55ff2806a47c1730316ab5e3b4b76a6
https://doi.org/10.1158/2326-6074.tumimm18-b88
https://doi.org/10.1158/2326-6074.tumimm18-b88