Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sreenivasa Reedy Mundla"'
Autor:
Karen L. Huss, Charles R. Heap, William T. McMillen, David K. Clawson, Jonathan M. Yingling, J. Scott Sawyer, Robert M. Campbell, Matthew D. Voss, Bryan D. Anderson, Chi Hsin R. King, Elizabeth A. Dierks, Hong Yu Li, Wang Yan, Lei Yan, Sreenivasa Reedy Mundla, Karen S. Britt, Denis J. McCann
Publikováno v:
Journal of Medicinal Chemistry. 51:2302-2306
In our continuing effort to expand the SAR of the quinoline domain of dihydropyrrolopyrazole series, we have discovered compound 15d, which demonstrated the antitumor efficacy with oral bioavailability. This effort also demonstrated that the PK/PD in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74284fcfb2d481b7bc2d3fa3c78f84f8
https://doi.org/10.1021/jm701199p
https://doi.org/10.1021/jm701199p
Autor:
Charles R. Heap, Jill R. Wagner, Lei Yan, Sreenivasa Reedy Mundla, Wang Yan, William T. McMillen, Ku X. Lu, David K. Clawson, Bryan D. Anderson, Chi Hsin R. King, Hong Yu Li, Karen S. Britt, Robert M. Campbell, Jonathan M. Yingling, Matthew Ernst Voss
Publikováno v:
Journal of Medicinal Chemistry. 49:2138-2142
Novel dihydropyrrolopyrazole-substituted benzimidazoles were synthesized and evaluated in vitro as inhibitors of transforming growth factor-beta type I receptor (TGF-beta RI), TGF-beta RII, and mixed lineage kinase-7 (MLK-7). These compounds were fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5274b1d7d4f5ea6265cabe5cd42aed8
https://doi.org/10.1021/jm058209g
https://doi.org/10.1021/jm058209g