Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sreenivas Kanugula"'
Data from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Germ-line mutations in BRCA2 have been linked to early-onset familial breast cancer. BRCA2 is known to play a key role in repairing double-strand breaks. Here, we describe the involvement of BRCA2 in O6-alkylguanine DNA alkyltransferase (AGT)–media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb6619d85d3a89b3dbac5caabed9e9d
https://doi.org/10.1158/0008-5472.c.6498177.v1
https://doi.org/10.1158/0008-5472.c.6498177.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 1 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f26f9072f886a6cbb3b25f229e501
https://doi.org/10.1158/0008-5472.22376379
https://doi.org/10.1158/0008-5472.22376379
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Table 1 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9b1df510650c2a3ff5b4b9f615f8c2
https://doi.org/10.1158/0008-5472.22376364.v1
https://doi.org/10.1158/0008-5472.22376364.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Information from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d878b4204495768a4849184643ac163
https://doi.org/10.1158/0008-5472.22376367.v1
https://doi.org/10.1158/0008-5472.22376367.v1
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 2 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cf58036a621f2441f76708cb8bc35b
https://doi.org/10.1158/0008-5472.22376376
https://doi.org/10.1158/0008-5472.22376376
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 3 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ae02a570635bb7e4b91c0379a053c1
https://doi.org/10.1158/0008-5472.22376373
https://doi.org/10.1158/0008-5472.22376373
Autor:
Shyam K. Sharan, Anthony E. Pegg, Philipp Kaldis, Diana C. Haines, Natalia A. Loktionova, Suhwan Chang, Kajal Biswas, Sreenivas Kanugula, Sergey G. Kuznetsov, Srividya Swaminathan, Subha Philip
Supplementary Figure 4 from Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092bf440618445facab1b748241cce4d
https://doi.org/10.1158/0008-5472.22376370.v1
https://doi.org/10.1158/0008-5472.22376370.v1
Autor:
Melissa Campion, Colin R Campbell, Erin D. Michaelson-Richie, Teshome B. Gherezghiher, Susith Wickramaratne, Sreenivas Kanugula, Anthony E. Pegg, Jamie Kurtz, Xun Ming, Natalia Y. Tretyakova
Publikováno v:
Biochemistry. 52:3171-3181
Although cytotoxic alkylating agents possessing two electrophilic reactive groups are thought to act by cross-linking cellular biomolecules, their exact mechanisms of action have not been established. In cells, these compounds form a mixture of DNA l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c44c7dfde0de32e6849f6f06be9f0f
https://doi.org/10.1021/bi400273m
https://doi.org/10.1021/bi400273m
Autor:
Natalia Y. Tretyakova, Delshanee Kotandeniya, Uthpala Seneviratne, Daniel P Murphy, Anthony E. Pegg, Rebecca Guza, Sreenivas Kanugula
Publikováno v:
Chemical Research in Toxicology. 24:1966-1975
O(6)-POB-dG (O(6)-[4-oxo-4-(3-pyridyl)but-1-yl]deoxyguanosine) are promutagenic nucleobase adducts that arise from DNA alkylation by metabolically activated tobacco-specific nitrosamines such as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a31d6fef79dd6a0a330629f0575eb5
https://doi.org/10.1021/tx2002993
https://doi.org/10.1021/tx2002993
Autor:
Anthony J. Michael, Robert T. Green, Colin Hanfrey, Anthony E. Pegg, Xiaojing Wang, Sreenivas Kanugula, Katherine A. Elliott, Diane E. McCloskey
Publikováno v:
Molecular Microbiology. 81:1109-1124
Summary We have identified gene fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase (AdoMetDC, speD) and aminopropyltransferase (speE) orthologues in diverse bacterial phyla. Both domains are functionally active and we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e33c3487db62a66e72a0bf3a8bbcb0
https://doi.org/10.1111/j.1365-2958.2011.07757.x
https://doi.org/10.1111/j.1365-2958.2011.07757.x