Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sreejith J Varma"'
Autor:
Gabriel Piedrafita, Sreejith J Varma, Cecilia Castro, Christoph B Messner, Lukasz Szyrwiel, Julian L Griffin, Markus Ralser
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001468 (2021)
The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken-egg dilemma, which describes that enzymes are made from the very
Externí odkaz:
https://doaj.org/article/21656b2790fa4e38b64a797d017961a5
Publikováno v:
Current Opinion in Systems Biology
Current Opinion in Systems Biology, 28
Current Opinion in Systems Biology 28 (2021)
Current Opinion in Systems Biology, 28
Current Opinion in Systems Biology 28 (2021)
Metabolism is executed by an efficient, interconnected and ancient biochemical system, the metabolic network. Its evolutionary origins are, however, barely understood. We here discuss that because of niche adaptation, the evolutionary selection actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6678943800e6dcd235092d40ca8ead
Autor:
Sreejith J. Varma, Christoph B. Messner, Lukasz Szyrwiel, Markus Ralser, Julian L. Griffin, Gabriel Piedrafita, Cecilia Castro
How metabolic pathways emerged in early evolution remains largely unknown. Recently discovered chemical networks driven by iron and sulfur resemble reaction sequences found within glycolysis, gluconeogenesis, the oxidative and reductive Krebs cycle,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86b0cb52ebecf2ac3ef08d1d3b0bfe2
https://doi.org/10.1101/2020.08.11.245860
https://doi.org/10.1101/2020.08.11.245860
Publikováno v:
Chemical Reviews
Chemical Reviews, American Chemical Society, 2020, 120 (15), pp.7708-7744. ⟨10.1021/acs.chemrev.0c00191⟩
Chemical Reviews, 2020, 120 (15), pp.7708-7744. ⟨10.1021/acs.chemrev.0c00191⟩
Chemical Reviews, American Chemical Society, 2020, 120 (15), pp.7708-7744. ⟨10.1021/acs.chemrev.0c00191⟩
Chemical Reviews, 2020, 120 (15), pp.7708-7744. ⟨10.1021/acs.chemrev.0c00191⟩
International audience; Prebiotic chemistry aims to explain how the biochemistry of life as we know it came to be. Most efforts in this area have focused on provisioning compounds of importance to life by multi-step synthetic routes that do not resem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d19505824bed97033ff46bee76ff9b8
Autor:
Elodie Chevallot-Beroux, Kamila B. Muchowska, Sreejith J. Varma, Joseph Moran, Lucas Lethuillier-Karl, Guang Li
Publikováno v:
Nature Ecology & Evolution
Nature ecology & evolution
Nature ecology & evolution
The reverse tricarboxylic acid (rTCA) cycle (also known as the reverse Krebs cycle) is a central anabolic biochemical pathway whose origins are proposed to trace back to geochemistry, long before the advent of enzymes, RNA or cells, and whose imprint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3514bce55a8500e02a8d5e391dbc4f8
https://doi.org/10.1038/s41559-017-0311-7
https://doi.org/10.1038/s41559-017-0311-7
Autor:
William Martin, Kamila B. Muchowska, Mingquan Yu, Masaru K. Nobu, Martina Preiner, Karl Kleinermanns, Yoichi Kamagata, Sreejith J. Varma, Harun Tüysüz, Joseph Moran, Kensuke Igarashi
Hydrogen gas, H2, is generated in alkaline hydrothermal vents from reactions of iron containing minerals with water during a geological process called serpentinization. It has been a source of electrons and energy since there was liquid water on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a93d483b8a5ee7d4aafc99a515f233
Publikováno v:
Nature. 593:E3-E3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13b9d48507da5bae4280a3dbed33b567
https://doi.org/10.1038/s41586-021-03383-9
https://doi.org/10.1038/s41586-021-03383-9
Autor:
Jino George, Thibault Chervy, Anoop Thomas, Atef Shalabney, James A. Hutchison, Thomas W. Ebbesen, Cyriaque Genet, Marian Dryzhakov, Eloïse Devaux, Xiaolan Zhong, Sreejith J. Varma, Joseph Moran
Publikováno v:
Angewandte Chemie (International Ed. in English)
The ground‐state deprotection of a simple alkynylsilane is studied under vibrational strong coupling to the zero‐point fluctuations, or vacuum electromagnetic field, of a resonant IR microfluidic cavity. The reaction rate decreased by a factor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343f8cb325adf20ecec0f668db27e9ca
https://doi.org/10.1002/anie.201605504
https://doi.org/10.1002/anie.201605504
How core biological metabolism initiated and why it uses the intermediates, reactions and pathways that it does remains unclear. Life builds its molecules from CO2 and breaks them down to CO2 again through the intermediacy of just five metabolites th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5875a3d4f7e43c2922911e61fe59b6eb
https://doi.org/10.26434/chemrxiv.7178930
https://doi.org/10.26434/chemrxiv.7178930
Publikováno v:
Nature Ecology & Evolution
Autotrophic theories for the origin of life propose that CO2 was the carbon source for primordial biosynthesis. Among the six known CO2 fixation pathways in nature, the acetyl-CoA (AcCoA; or Wood–Ljungdahl) pathway is the most ancient, and relies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a7e6d115e178b5f861ade71f22eced