Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sreedharan Nair Sabarinath"'
Autor:
M. M. Hamdi, Ehab S. El Desoky, Michael Bewernitz, Sreedharan Nair Sabarinath, Hartmut Derendorf
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 37:352-355
Summary What is Known and Objective: Individualization of carbamazepine (CBZ) dosage regimen in patients with epilepsy based on based on therapeutic drug monitoring (TDM) followed by estimation of pharmacokinetic (PK) parameters can help in better co
Autor:
Kim F. M. Keijzers, Adrie W. Bruijnzeel, Hidetaka Yamada, Sreedharan Nair Sabarinath, Elysia Small, Firas Kobeissy, Rayna M. Bauzo, Mahendra Bishnoi, Hartmut Derendorf, Irma A. van Tuijl, Hina P. Shah
Publikováno v:
Pharmacology Biochemistry and Behavior. 95:401-409
Epidemiological studies indicate that parental smoking increases the risk for smoking in children. However, the underlying mechanisms by which parental smoking increases the risk for smoking are not known. The aim of these studies was to investigate
Autor:
Sreedharan Nair Sabarinath, Hartmut Derendorf, James R. Pauly, Jacqueline E. Geier, Elysia Small, Kate R. Yavarovich, Mark S. Gold, Hina P. Shah, Jake Davenport, Adrie W. Bruijnzeel, Hidetaka Yamada
Publikováno v:
Psychopharmacology. 208:143-158
Tobacco smoke contains nicotine and many other compounds that act in concert on the brain reward system. Therefore, animal models are needed that allow the investigation of chronic exposure to the full spectrum of tobacco smoke constituents.The aim o
Autor:
Bindu Murthy, Christoph N. Seubert, April M. Barbour, Sreedharan Nair Sabarinath, Maria B. Grant, Hartmut Derendorf, Stephan Schmidt, Donna Skee
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:2773-2776
Ceftobiprole is a promising new broad-spectrum cephalosporin with activity against several multidrug-resistant gram-positive and gram-negative species, including methicillin-resistant Staphylococcus aureus . In order to make efficacy predications aga
Publikováno v:
Journal of Chromatography B. 864:52-60
In the present studies, to give momentum to traditionally low throughput pharmacokinetic screening, a bioanalytical method based on the concept of sample pooling for simultaneous bioanalysis of multiple compounds is discussed. A sensitive, selective,
Autor:
Philippe Prokocimer, Sreedharan Nair Sabarinath, Hartmut Derendorf, Christoph N. Seubert, Maria B. Grant, Martina Sahre, Carisa DeAnda
Plasma concentrations of antimicrobial drugs have long been used to correlate exposure with effect, yet one cannot always assume that unbound plasma and tissue concentrations are similar. Knowledge about unbound tissue concentrations is important in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453747a08476aa02faa30bf21a928343
https://europepmc.org/articles/PMC3789129/
https://europepmc.org/articles/PMC3789129/
Suppression of ciprofloxacin-induced resistant Pseudomonas aeruginosa in a dynamic kill curve system
Autor:
Sreedharan Nair Sabarinath, Kenneth H. Rand, Hartmut Derendorf, Judith A. Johnson, Benjamin M. Wu
Publikováno v:
International journal of antimicrobial agents. 37(6)
Current dosing approaches for treating microbial infections ignore resistant subpopulations. A clinical isolate of Pseudomonas aeruginosa was cultured in a dynamic in vitro kill curve system designed to simulate the half-lives of drugs in order to ev
Publikováno v:
Clinical Pharmacology: Current Topics and Case Studies ISBN: 9783709101438
The success of antibiotic therapy depends on complex interplay between the administered drug, its mechanism of action, concentration at site of infection, and complexity or severity of infection. Therapeutic response to an anti-infective agent or its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dae734c2da373aaae870a2a9011dc74
https://doi.org/10.1007/978-3-7091-0144-5_10
https://doi.org/10.1007/978-3-7091-0144-5_10
Autor:
Darren Abbanat, Hartmut Derendorf, April M. Barbour, Sue Sha, Sreedharan Nair Sabarinath, Prasarn Manitpisitkul, Stephan Schmidt
Linezolid is the first FDA-approved oxazolidinone with activity against clinically important gram-positive pathogens, including methicillin (meticillin)-resistant Staphylococcus aureus (MRSA). RWJ-416457 is a new oxazolidinone with an antimicrobial s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b990f680c080d9947611ceaad291b0f6
https://europepmc.org/articles/PMC2786350/
https://europepmc.org/articles/PMC2786350/
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 36(1)
Exposure of inhaled corticosteroids (ICSs) in pediatrics results in adrenal suppression and growth inhibition. The objective of this study was to assess the relationship of ICS mediated growth retardation with cortisol suppression in asthmatic childr