Autonomous Optimization of Targeted Stimulation of Neuronal Networks.

Autor: Sreedhar S Kumar, Jan Wülfing, Samora Okujeni, Joschka Boedecker, Martin Riedmiller, Ulrich Egert

Publikováno v: PLoS Computational Biology, Vol 12, Iss 8, p e1005054 (2016)

Driven by clinical needs and progress in neurotechnology, targeted interaction with neuronal networks is of increasing importance. Yet, the dynamics of interaction between intrinsic ongoing activity in neuronal networks and their response to stimulat

Externí odkaz: https://doaj.org/article/e7297c58244742ab8049b0539d8d7e9e

A modulated template-matching approach to improve spike sorting of bursting neurons

Autor: Payam S. Shabestari, Alessio P. Buccino, Sreedhar S. Kumar, Alessandra Pedrocchi, Andreas Hierlemann

Publikováno v: 2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
IEEE Biomed Circuits Syst Conf

In extracellular neural electrophysiology, individual spikes have to be assigned to their cell of origin in a procedure called “spike sorting”. Spike sorting is an unsupervised problem, since no ground-truth information is generally available. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f1403a30a7e935427f77a203d32b9d
https://doi.org/10.1109/biocas49922.2021.9644995

Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins

Autor: Thomas Buettner, Laura Rose, Tomas Malinauskas, Peter Schierack, Marc Emmenegger, Dirk Roggenbuck, Clemens Sommer, Adriano Aguzzi, Martin F. Sprinzl, Karl J. Lackner, Sreedhar S. Kumar, Vishalini Emmenegger, Katrin Frauenknecht

Publikováno v: PLoS Pathogens, 17 (12)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 12, p e1010118 (2021)

Antiphospholipid antibodies (aPL), assumed to cause antiphospholipid syndrome (APS), are notorious for their heterogeneity in targeting phospholipids and phospholipid-binding proteins. The persistent presence of Lupus anticoagulant and/or aPL against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4c917fbd620ddf715e66dab55da121
https://doi.org/10.1371/journal.ppat.1010118

DDE models of the glucose-insulin system: a useful tool for the artificial pancreas

Autor: Jude Dzevela Kong, Sreedhar S. Kumar, Pasquale Palumbo

Publikováno v: Managing Complexity, Reducing Perplexity in Biological Systems, pp. 109–117, 2014
info:cnr-pdr/source/autori:J. Kong, S.S. Kumar, P. Palumbo/titolo:DDE models of the glucose-insulin system: a useful tool for the artificial pancreas/titolo_volume:Managing Complexity, Reducing Perplexity in Biological Systems/curatori_volume:/editore:/anno:2014
Managing Complexity, Reducing Perplexity ISBN: 9783319037585

Delay differential equations are widely adopted in life sciences: including delays explicitly in mathematical models allows to simulate the systems under investigation more accurately, without the use of auxiliary fictitious compartments. This work d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8e5ed44d9aa6e715a1a9085b4fe956
https://publications.cnr.it/doc/288470

Regulation of the Human Plasma Glycemia by Means of Glucose Measurements and Subcutaneous Insulin Administration

Autor: Sreedhar S. Kumar, Simona Panunzi, A. De Gaetano, Pasquale Palumbo, Pierdomenico Pepe, Jude Dzevela Kong

Publikováno v: ICONS
3rd IFAC International Conference on Intelligent Control and Automation Science (ICONS13), pp. 96–101, ChengDu (Cina), 2013
info:cnr-pdr/source/autori:P. Palumbo, P. Pepe, J.D. Kong, S.S. Kumar, S. Panunzi, A. De Gaetano/congresso_nome:3rd IFAC International Conference on Intelligent Control and Automation Science (ICONS13)/congresso_luogo:ChengDu (Cina)/congresso_data:2013/anno:2013/pagina_da:96/pagina_a:101/intervallo_pagine:96–101

A glucose control problem is considered, with the aim to regulate a basal hyperglycemic state down to a safe euglycemic level. A discrete Delay Differential Equation (DDE) model of the glucose-insulin system is considered, that properly takes into ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1dbd8cdbf2b28dc287adbdaceaa0ec
http://hdl.handle.net/10281/246599