Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sree N Sreenath"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97130 (2014)
Few of >150 published cell cycle modeling efforts use significant levels of data for tuning and validation. This reflects the difficultly to generate correlated quantitative data, and it points out a critical uncertainty in modeling efforts. To devel
Externí odkaz:
https://doaj.org/article/a81b912fe34b4838b43431951f82fe21
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e38275 (2012)
Cytometry of asynchronous proliferating cell populations produces data with an extractable time-based feature embedded in the frequency of clustered, correlated events. Here, we present a specific case of general methodology for calculating dynamic e
Externí odkaz:
https://doaj.org/article/8f5e1168eaa74f8688181fbf0d8354b9
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30870 (2012)
An imprecise quantitative sense for the oscillating levels of proteins and their modifications, interactions, and translocations as a function of the cell cycle is fundamentally important for a cartoon/narrative understanding for how the cell cycle w
Externí odkaz:
https://doaj.org/article/cec9bc4623664e4ba85bda871bc3588d
Autor:
Eswar Shankar, Meenakshi Shukla, Sanjay Gupta, Sree N. Sreenath, Sanjeev Shukla, Jayant Avva, Michael C. Weis
Publikováno v:
Cells
Cells, Vol 8, Iss 3, p 201 (2019)
Volume 8
Issue 3
Cells, Vol 8, Iss 3, p 201 (2019)
Volume 8
Issue 3
Phosphatidylinositol 3&prime
OH kinase (PI3K)-Akt and transcription factor NF-&kappa
B are important molecules involved in the regulation of cell proliferation, apoptosis, and oncogenesis. Both PI3K-Akt and Nuclear Factor-kappaB (NF-&kappa<
OH kinase (PI3K)-Akt and transcription factor NF-&kappa
B are important molecules involved in the regulation of cell proliferation, apoptosis, and oncogenesis. Both PI3K-Akt and Nuclear Factor-kappaB (NF-&kappa<
Publikováno v:
Journal of Flow Visualization and Image Processing. 16:137-158
Autor:
Sree N. Sreenath
Publikováno v:
International Journal of General Systems. 37:537-552
Identification of functional modules in complex systems is becoming an important challenge in many scientific disciplines from biology to social sciences. Here we introduce the concept of cohesion as a guide for modularization. General systems treatm
Autor:
Olaf Wolkenhauer, Thomas Millat, Kwang-Hyun Cho, Radina P. Soebiyanto, Sree N. Sreenath, Jayant Avva
Publikováno v:
Biosystems. 92:270-281
Bistable systems play an important role in the functioning of living cells. Depending on the strength of the necessary positive feedback one can distinguish between (irreversible) "one-way switch" or (reversible) "toggle-switch" type behavior. Beside
Publikováno v:
Biosystems. 90:830-842
In this work, we search for coordination as an organizing principle in a complex signaling system using a multilevel hierarchical paradigm. The objective is to explain the underlying mechanism of Interferon (IFN γ ) induced JAK-STAT (specifically JA
Publikováno v:
IET Systems Biology. 1:33-40
Networks of signaling pathways provide a robust mechanism for cells to respond to various biological stimuli. Cell adaptation through the viewpoint of an organising principle between two interconnected pathways – mitogen-activated protein kinase (M
Publikováno v:
Environment, Development and Sustainability. 8:313-349
In this paper we develop a novel, comprehensive method for estimating the global human carrying capacity in reference to food production factors and levels of food consumption. Other important interrelated dimensions of carrying capacity such as ener