Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Srdjan Gasic"'
Autor:
Ondrej Mihola, Vladimir Landa, Florencia Pratto, Kevin Brick, Tatyana Kobets, Fitore Kusari, Srdjan Gasic, Fatima Smagulova, Corinne Grey, Petr Flachs, Vaclav Gergelits, Karel Tresnak, Jan Silhavy, Petr Mlejnek, R. Daniel Camerini-Otero, Michal Pravenec, Galina V. Petukhova, Zdenek Trachtulec
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse and human PRDM9 proteins catal
Externí odkaz:
https://doaj.org/article/03a0d82fd99840bf996152ad7bf19c03
Publikováno v:
Mammalian Genome. 33:590-605
Aneuploidy (abnormal chromosome number) accompanies reduced ovarian function in humans and mice, but the reasons behind this concomitance remain underexplored. Some variants in the human gene encoding histone-3-lysine-4,36-trimethyltransferase PRDM9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50d0630d6990c1e9513396874e3f3fb
https://doi.org/10.1007/s00335-022-09954-z
https://doi.org/10.1007/s00335-022-09954-z
Autor:
Klara Krivankova, Tatyana Kobets, Srdjan Gasic, Zdenek Trachtulec, Ondrej Mihola, Eliska Linhartova, John C. Schimenti
Publikováno v:
Chromosoma. 129:69-82
Long transgenes are often used in mammalian genetics, e.g., to rescue mutations in large genes. In the course of experiments addressing the genetic basis of hybrid sterility caused by meiotic defects in mice bearing different alleles of Prdm9, we dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0f636a07f2a85b5c8f26ea0dfc7477
https://doi.org/10.1007/s00412-019-00730-8
https://doi.org/10.1007/s00412-019-00730-8
Autor:
Mihola, Ondrej, Landa, Vladimir, Pratto, Florencia, Brick, Kevin, Kobets, Tatyana, Kusari, Fitore, Srdjan Gasic, Smagulova, Fatima, Grey, Corinne, Flachs, Petr, Vaclav Gergelits, Tresnak, Karel, Silhavy, Jan, Mlejnek, Petr, R. Daniel Camerini-Otero, Pravenec, Michal, Petukhova, Galina V., Trachtulec, Zdenek
Additional file 1: Fig. S1. Translations of mRNAs from rat Prdm9 mutants (red) described in Fig. 1 aligned in the SET domain with homologs from other species. G278, N320 and Y341 are amino acids essential for H3K4 trimethylation activity of PRDM9 [12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175f9a26403fbde36a8a7dd57c4c431f
Autor:
Vladimír Landa, Fatima Smagulova, Florencia Pratto, Ondrej Mihola, Michal Pravenec, Srdjan Gasic, R. Daniel Camerini-Otero, Petr Flachs, Corinne Grey, Fitore Kusari, Karel Tresnak, Vaclav Gergelits, Galina V. Petukhova, Petr Mlejnek, Zdenek Trachtulec, Tatyana Kobets, Kevin Brick, Jan Silhavy
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
BMC Biology, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, BioMed Central, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
BMC Biology, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BMC Biology, BioMed Central, 2021, 19 (1), pp.86. ⟨10.1186/s12915-021-01017-0⟩
BackgroundVertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse and human PRDM9 proteins catalyze H3K4me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970f33764fc5f3a889d99e6f80d17876
https://pubmed.ncbi.nlm.nih.gov/33910563
https://pubmed.ncbi.nlm.nih.gov/33910563