Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sravya Kommineni"'
Autor:
Ralda Nehme, Emanuela Zuccaro, Sulagna Dia Ghosh, Chenchen Li, John L. Sherwood, Olli Pietilainen, Lindy E. Barrett, Francesco Limone, Kathleen A. Worringer, Sravya Kommineni, Ying Zang, Davide Cacchiarelli, Alex Meissner, Rolf Adolfsson, Stephen Haggarty, Jon Madison, Matthias Muller, Paola Arlotta, Zhanyan Fu, Guoping Feng, Kevin Eggan
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2509-2523 (2018)
Summary: Transcription factor programming of pluripotent stem cells (PSCs) has emerged as an approach to generate human neurons for disease modeling. However, programming schemes produce a variety of cell types, and those neurons that are made often
Externí odkaz:
https://doaj.org/article/b9fd469e3b2948599a14ab277d3059fe
Autor:
Robert J. Ihry, Max R. Salick, Daniel J. Ho, Marie Sondey, Sravya Kommineni, Steven Paula, Joe Raymond, Beata Henry, Elizabeth Frias, Qiong Wang, Kathleen A. Worringer, Chaoyang Ye, Carsten Russ, John S. Reece-Hoyes, Robert C. Altshuler, Ranjit Randhawa, Zinger Yang, Gregory McAllister, Gregory R. Hoffman, Ricardo Dolmetsch, Ajamete Kaykas
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 616-630.e6 (2019)
Summary: Human pluripotent stem cells (hPSCs) generate a variety of disease-relevant cells that can be used to improve the translation of preclinical research. Despite the potential of hPSCs, their use for genetic screening has been limited by techni
Externí odkaz:
https://doaj.org/article/39ad2f3ea8e94904a721c8785edecb36
Autor:
Michael F. Wells, James Nemesh, Sulagna Ghosh, Jana M. Mitchell, Max R. Salick, Curtis J. Mello, Daniel Meyer, Olli Pietilainen, Federica Piccioni, Ellen J. Guss, Kavya Raghunathan, Matthew Tegtmeyer, Derek Hawes, Anna Neumann, Kathleen A. Worringer, Daniel Ho, Sravya Kommineni, Karrie Chan, Brant K. Peterson, Joseph J. Raymond, John T. Gold, Marco T. Siekmann, Emanuela Zuccaro, Ralda Nehme, Ajamete Kaykas, Kevin Eggan, Steven A. McCarroll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdde615d08b61500d6ebedf50ae67f53
https://hdl.handle.net/11577/3483040
https://hdl.handle.net/11577/3483040
Autor:
Matthew Tegtmeyer, Karrie Chan, Curtis J. Mello, Brant K. Peterson, Daniel J. Ho, Steven A. McCarroll, Jana M. Mitchell, Sulagna Ghosh, Federica Piccioni, Kathleen A. Worringer, Sravya Kommineni, Kavya Raghunathan, Kevin Eggan, Joseph J. Raymond, Michael F. Wells, James Nemesh, Ralda Nehme, Derek C. Hawes, Anna Neumann, Daniel Meyer
SUMMARYVariation in the human genome contributes to abundant diversity in human traits and vulnerabilities, but the underlying molecular and cellular mechanisms are not yet known, and will need scalable approaches to accelerate their recognition. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9cf85eb4e39a5f2090d1f73abd85148
https://doi.org/10.1101/2021.11.08.467815
https://doi.org/10.1101/2021.11.08.467815
Autor:
Daniel Baird, John H. Brumell, Kirsty Hooper, Leon Murphy, Jonathan M. Goodwin, Jeff Saunders, Sreekanth R. Rouduri, Sravya Kommineni, Archana Jha, Aylwin Ng, Oliver Florey, Menghao Wei, Taoyingnan Li, Mark R. Chance, Ward G. Walkup, Timothy Lehmberg, Sagar R. Budhe, Qing Tang, Jorge Garcia-Fortanet, Yaya Fan, Asmita Agrawal, Katherine Fletcher, Brent A. Appleton, Andrea Ballabio, Chieko Kishi-Itakura, Janna Kiselar
Publikováno v:
Science Advances. 7
Adaptive changes in lysosomal capacity are driven by the transcription factors TFEB and TFE3 in response to increased autophagic flux and endolysosomal stress, yet the molecular details of their activation are unclear. LC3 and GABARAP members of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b681f41d389eb5ca197aa8dd032ad11
https://doi.org/10.1126/sciadv.abj2485
https://doi.org/10.1126/sciadv.abj2485
Autor:
Sagar R. Budhe, Qing Tang, Timothy Lehmberg, Andrea Ballabio, Katherine Fletcher, Menghao Wei, Asmita Agrawal, Daniel Baird, Sreekanth R. Rouduri, Ward G. Walkup, Oliver Florey, Archana Jha, John H. Brumell, Jorge Garcia-Fortanet, Leon Murphy, Sravya Kommineni, Kirsty Hooper, Jonathan M. Goodwin, Chieko Kishi-Itakura, Brent A. Appleton, Yaya Fan, Aylwin Ng, Janna Kiselar, Jeffrey J. Saunders, Mark R. Chance, Taoyingnan Li
Adaptive changes in lysosomal capacity are driven by the transcription factors TFEB and TFE3 in response to increased autophagic flux and endolysosomal stress, yet the molecular details of their activation are unclear. LC3 and GABARAP members of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::539ee4ceb1fc409289003ea1203b8149
https://doi.org/10.1101/2021.02.22.432209
https://doi.org/10.1101/2021.02.22.432209
Autor:
Karrie Chan, Kevin Eggan, Jospeph J Raymond, Kathleen A. Worringer, Ellen J. Hill, Olli Pietilainen, Jana M. Mitchell, Federica Piccioni, Ajamete Kaykas, Marco T Siekmann, Sravya Kommineni, Brant K. Peterson, Daniel J. Ho, Max R. Salick, Michael F. Wells, Ralda Nehme
SUMMARYNeural progenitor cells (NPCs) are essential to brain development and their dysfunction is linked to several disorders, including autism, Zika Virus Congenital Syndrome, and cancer. Understanding of these conditions has been improved by advanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3c598b05c8e09272082fcac796c5b1
https://doi.org/10.1101/476440
https://doi.org/10.1101/476440
Autor:
Lindy E. Barrett, John L. Sherwood, Rolf Adolfsson, Stephen J. Haggarty, Davide Cacchiarelli, Ying Zang, Olli Pietilainen, Sulagna Ghosh, Guoping Feng, Francesco Limone, Ralda Nehme, Emanuela Zuccaro, Alexander Meissner, Matthias Müller, Kathleen A. Worringer, Chenchen Li, Jon M. Madison, Kevin Eggan, Zhanyan Fu, Paola Arlotta, Sravya Kommineni
Publikováno v:
Elsevier
Cell Reports, Vol 23, Iss 8, Pp 2509-2523 (2018)
Cell reports
Cell Reports
Cell Reports, Vol 23, Iss 8, Pp 2509-2523 (2018)
Cell reports
Cell Reports
SUMMARY Transcription factor programming of pluripotent stem cells (PSCs) has emerged as an approach to generate human neurons for disease modeling. However, programming schemes produce a variety of cell types, and those neurons that are made often r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c234acc62b5124d34fca1748593c822b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-148731
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-148731
Autor:
Gregory R. Hoffman, Kathleen A. Worringer, Ranjit Randhawa, Sravya Kommineni, Robert J. Ihry, Gregory McAllister, Marie Sondey, Steven Paula, Ricardo E. Dolmetsch, Zinger Yang, Ajamete Kaykas, Elizabeth Frias, Daniel J. Ho, Joe Raymond, Bob Altshuler, Max R. Salick, Carsten Russ, John S. Reece-Hoyes
Publikováno v:
SSRN Electronic Journal.
Human pluripotent stem cells (hPSCs) generate a wide variety of disease-relevant cells that can be used to improve the translation of preclinical research. Despite the potential of hPSCs, their use for genetic screening has been limited because of te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c345a1bdb5c383f6a79f625d6ac07ed
https://doi.org/10.2139/ssrn.3189387
https://doi.org/10.2139/ssrn.3189387
Autor:
Elizabeth Frias, Carsten Russ, Sravya Kommineni, Robert J. Ihry, William C. Forrester, Marie Sondey, Kraig M. Theriault, Chaoyang Ye, Ajamete Kaykas, Daniel J. Ho, Ricardo E. Dolmetsch, Kathleen A. Worringer, Max R. Salick, Gregory R. Hoffman, Gregory McAllister, Tripti Kulkarni, Julie Chen, Zinger Yang, Ranjit Randhawa, John S. Reece-Hoyes
Publikováno v:
Nature medicine. 24(7)
CRISPR/Cas9 has revolutionized our ability to engineer genomes and conduct genome-wide screens in human cells1–3. Whereas some cell types are amenable to genome engineering, genomes of human pluripotent stem cells (hPSCs) have been difficult to eng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f9a2862fe1c264657cc670822d146f
https://pubmed.ncbi.nlm.nih.gov/30017531
https://pubmed.ncbi.nlm.nih.gov/30017531