Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sravanthi Reddy Pailla"'
Autor:
Sravanthi Reddy Pailla, Sunitha Sampathi, Vijayabhaskarreddy Junnuthula, Sravya Maddukuri, Sujatha Dodoala, Sathish Dyawanapelly
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 978 (2022)
The purpose of our study was to improve the solubility, bioavailability, and efficacy of zotepine (ZTP) by brain-targeted intranasal delivery of microemulsion (ME) and its physicochemical properties, the pharmacokinetic and pharmacodynamic parameters
Externí odkaz:
https://doaj.org/article/e1de9bf3f04e469fa8a0ec36f8c98b7c
Publikováno v:
Drug delivery and translational research. 10(5)
Ibrutinib (IBR) is the choice of drug for the treatment of chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL). IBR has low oral bioavailability of 2.9% owing to its high first pass metabolism. Present study was aimed to develop the na
Publikováno v:
AAPS PharmSciTech. 20
Present study was aimed to increase the oral bioavailability and reduce the fast fed variability of Ibrutinib by developing nanosuspension by simple precipitation-ultrasonication method. A three factor, three level, box-behnken design was used for fo
Autor:
Maruthi A J, D. Sujatha, Sunitha Sampathi, Saurabh Shah, Sravanthi Reddy Pailla, Hanumanth Srikanth Cheruvu, Nagarjun Rangaraj
Publikováno v:
AAPS PharmSciTech. 20(7)
The goal of the present investigation is to formulate febuxostat (FXT) self-nanoemulsifying delivery systems (liquid SNEDDS, solid SNEDDS, and pellet) to ameliorate the solubility and bioavailability. To determine the self-nanoemulsifying region, ter
Autor:
Ramdas Ramavath, Sreekanth Talluri, Veerabhadra Swamy Challa, Nagarjun Rangaraj, Sunitha Sampathi, Nandkumar Doijad, Sravanthi Reddy Pailla
Publikováno v:
Daru
BACKGROUND: Zotepine (ZTP), an antipsychotic drug is well tolerated and particularly effective for treating negative symptoms of psychosis. But is limited by low oral bioavailability caused by substantial first pass metabolism and thereby less amount
Autor:
Pravin Patel, Sunitha Sampathi, Nagarjun Rangaraj, Hanumanth Srikanth Cheruvu, Sujatha Dodoala, Sravanthi Reddy Pailla
Publikováno v:
AAPS PharmSciTech. 20
The aim of the current investigation was to generate a self-nanoemulsifying drug delivery system (SNEDDS) of gliclazide (GCZ) to address the poor solubility and bioavailability. Ternary phase diagram was created with Capmul MCM C8 NF (oil), Cremophor
Publikováno v:
Pulmonary pharmacologytherapeutics. 54