Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sravan Kumar Patel"'
Autor:
Sravan Kumar Patel, Hrushikesh Agashe, Dorothy L. Patton, Yvonne Sweeney, May A. Beamer, Craig W. Hendrix, Sharon L. Hillier, Lisa C. Rohan
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
Tenofovir (TFV) is an adenosine nucleotide analog with activity against HIV and HSV-2. Secondary analyses of clinical trials evaluating TFV gel as pre-exposure prophylaxis (PrEP) for HIV have shown that gel formulations of TFV provide significant pro
Externí odkaz:
https://doaj.org/article/4f7fdef639424cfe93dc0365ccf457bf
Autor:
Kunal Jhunjhunwala, Charles W. Dobard, Sunita Sharma, Natalia Makarova, Angela Holder, Chuong Dinh, James Mitchell, Lin Wang, Junmei Zhang, Sravan Kumar Patel, Walid Heneine, Lisa C. Rohan
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1110 (2021)
Receptive anal intercourse (RAI) contributes significantly to HIV acquisition underscoring the need to develop HIV prevention options for populations engaging in RAI practices. We explored the feasibility of formulating rectal suppositories with pote
Externí odkaz:
https://doaj.org/article/3ac71f755747494c80bf422307adebd9
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 184 (2019)
Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-co-glyco
Externí odkaz:
https://doaj.org/article/c0af737a500a4fdab440c36faa91ed5e
Autor:
Kiran Vasudeva, Karl Andersen, Bree Zeyzus-Johns, T Kevin Hitchens, Sravan Kumar Patel, Anthony Balducci, Jelena M Janjic, John A Pollock
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90589 (2014)
Chronic neuropathic pain following surgery represents a serious worldwide health problem leading to life-long treatment and the possibility of significant disability. In this study, neuropathic pain was modeled using the chronic constriction injury (
Externí odkaz:
https://doaj.org/article/e15a1956cef5411b9cd1acabc34e64f8
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55802 (2013)
Cylcooxgenase-2 (COX-2) expressing macrophages, constituting a major portion of tumor mass, are involved in several pro-tumorigenic mechanisms. In addition, macrophages are actively recruited by the tumor and represent a viable target for anticancer
Externí odkaz:
https://doaj.org/article/01e9b9669f3a4a45b94d1e1d55600fb1
Autor:
Xin Tong, Sravan Kumar Patel, Jing Li, Dorothy Patton, Elaine Xu, Peter L. Anderson, Urvi Parikh, Yvonne Sweeney, Julie Strizki, Sharon L. Hillier, Lisa C. Rohan
Publikováno v:
Polymers; Volume 14; Issue 6; Pages: 1196
MK-2048 is a second-generation integrase inhibitor active against HIV, which has been applied vaginally using ring formulations. In this work, a nanoparticle-in-film technology was developed as a discrete pre-exposure prophylactic product option agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9188cdcf59728ea7269feb0c23b7bb
https://pubmed.ncbi.nlm.nih.gov/35335526
https://pubmed.ncbi.nlm.nih.gov/35335526
Autor:
Walid Heneine, James Mitchell, Natalia Makarova, Lisa C. Rohan, Lin Wang, Sravan Kumar Patel, Junmei Zhang, Sunita Sharma, Angela Holder, Chuong Dinh, Kunal Jhunjhunwala, Charles Dobard
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1110, p 1110 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1110, p 1110 (2021)
Volume 13
Issue 8
Receptive anal intercourse (RAI) contributes significantly to HIV acquisition underscoring the need to develop HIV prevention options for populations engaging in RAI practices. We explored the feasibility of formulating rectal suppositories with pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a28255c6996d80beca57812e47126aa
https://pubmed.ncbi.nlm.nih.gov/34452070
https://pubmed.ncbi.nlm.nih.gov/34452070
Autor:
Iman Taj Basha, Stuti M. Desai, Yuan Zou, Sam N. Rothstein, Ashlee C. Greene, Mostafa S. Shehabeldin, James Scott MacPherson, Yan Wang, Lisa C. Rohan, Charles Sfeir, Steven R. Little, Sravan Kumar Patel
Publikováno v:
International journal of pharmaceutics. 596
Currently, there is no compendial-level method to assess dissolution of particulate systems administered in the periodontal pocket. This work seeks to develop dissolution methods for extended release poly(lactic-co-glycolic acid) (PLGA) microspheres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbe2d9b5fd228abd8a6ef94b2d9611e
https://pubmed.ncbi.nlm.nih.gov/33486044
https://pubmed.ncbi.nlm.nih.gov/33486044
Publikováno v:
Advanced Drug Delivery Reviews. 177:113955
The female upper genital tract (UGT) hosts important reproductive organs including the cervix, uterus, fallopian tubes, and ovaries. Several pathologies affect these organ systems such as infections, reproductive issues, structural abnormalities, can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4adec0c428745784c0a9908a5f6e01
https://doi.org/10.1016/j.addr.2021.113955
https://doi.org/10.1016/j.addr.2021.113955
Autor:
Lisa C. Rohan, Sravan Kumar Patel
Publikováno v:
Drug Delivery and Translational Research. 7:775-795
Sexual intercourse (vaginal and anal) is the predominant mode of human immunodeficiency virus (HIV) transmission. Topical microbicides used in an on-demand format (i.e., immediately before or after sex) can be part of an effective tool kit utilized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36149115e5fb9249af7fa97de389af69
https://doi.org/10.1007/s13346-017-0385-4
https://doi.org/10.1007/s13346-017-0385-4