Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sravan K. Vanamala"'
Autor:
Meena Gujrati, Dzung H. Dinh, Chandramu Chetty, Sravan K. Vanamala, Jasti S. Rao, Christopher S. Gondi
Publikováno v:
Cell Signal
CD44 is implicated in cell-cell and cell-matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic potential in various cancers. In this study, we demonstrate that matrix metalloproteinase-9 (MMP-9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f38ecc8b0d4ab4521d442dadb76683
https://doi.org/10.1016/j.cellsig.2021.110011
https://doi.org/10.1016/j.cellsig.2021.110011
Autor:
Chandramu Chetty, Christopher S. Gondi, Jasti S. Rao, Meena Gujrati, Dzung H. Dinh, Sravan K. Vanamala
Publikováno v:
Cellular Signalling. 24:549-559
CD44 is implicated in cell-cell and cell-matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic potential in various cancers. In this study, we demonstrate that matrix metalloproteinase-9 (MMP-9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e4b4276161b71135878f728cfdbc38
https://doi.org/10.1016/j.cellsig.2011.10.008
https://doi.org/10.1016/j.cellsig.2011.10.008
Publikováno v:
Biochemical and Biophysical Research Communications. 395:367-372
In the present study, we investigated the cardiomyogenic potential of human umbilical cord blood (hUCB)-derived stem cells and whether stem cell treatment repairs the pathological hypertrophy induced by doxorubicin (DOX) in cultured neonatal rat card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513db77f89a190c18d6d6a3b0313f58a
https://doi.org/10.1016/j.bbrc.2010.04.021
https://doi.org/10.1016/j.bbrc.2010.04.021
Publikováno v:
Free Radical Biology and Medicine. 45:1723-1728
A proposed mechanism for the cardiotoxicity of doxorubicin (DOX) involves apoptosis in cardiomyocytes. In the study described here, we investigated the molecular basis for the differences in DOX-induced toxicity in adult rat cardiomyocytes (ARCM), ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e43dc331a07325d4dddfb1d4822033
https://doi.org/10.1016/j.freeradbiomed.2008.09.006
https://doi.org/10.1016/j.freeradbiomed.2008.09.006
Autor:
Praveen Bhoopathi, Jasti S. Rao, Sateesh Kunigal, Sajani S. Lakka, Sravan K. Vanamala, Chandramu Chetty
Publikováno v:
J Biol Chem
We previously showed that matrix metalloproteinase (MMP)-9 inhibition using an adenovirus-mediated delivery of MMP-9 small interfering RNA (Ad-MMP-9), caused senescence in medulloblastoma cells. Regardless of whether or not Ad-MMP-9 would induce apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b4a8e0c36098f5cf03374ca0b27b7a
https://doi.org/10.1074/jbc.m707931200
https://doi.org/10.1074/jbc.m707931200
Autor:
Shasi V. Kalivendi, Sonya Cunningham, Eugene H. Kaji, Balaraman Kalyanaraman, Eugene A. Konorev, Sravan K. Vanamala, Joy Joseph
Publikováno v:
Biochemical Journal. 389:527-539
Doxorubicin (DOX), a widely used antitumour drug, causes dose-dependent cardiotoxicity. Cardiac mitochondria represent a critical target organelle of toxicity during DOX chemotherapy. Proposed mechanisms include generation of ROS (reactive oxygen spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb97c09b7e44a14ced9b7bfbadf16079
https://doi.org/10.1042/bj20050285
https://doi.org/10.1042/bj20050285
Autor:
Jeffrey D. Klopfenstein, Dzung H. Dinh, Jasti S. Rao, Sreelatha Gopinath, Sravan K. Vanamala, Meena Gujrati
Publikováno v:
Cellular and molecular life sciences : CMLS. 66(24)
Nuclear factor of activated T cells (NFAT), a family of transcription factors, has been implicated in many cellular processes, including some cancers. Here, we characterize, for the first time, the role of NFAT3 in doxorubicin (DOX)-mediated apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313978da93016773e7511585834da37e
https://pubmed.ncbi.nlm.nih.gov/19784808
https://pubmed.ncbi.nlm.nih.gov/19784808
Publikováno v:
Biochemical and biophysical research communications. 386(2)
We have assessed the capacity of human umbilical cord blood (hUCB)-derived stem cells to differentiate into cardiomyocytes and repair angiotensin II induced insult in culture and in mouse hearts when injected. hUCB were able to differentiate into car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4461ae7af8dfe6e1c6b487aace0f51b7
https://pubmed.ncbi.nlm.nih.gov/19524549
https://pubmed.ncbi.nlm.nih.gov/19524549
Publikováno v:
Biochemical and Biophysical Research Communications. 426:668
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95ed850e402567fe5fafe3de819ce719
https://doi.org/10.1016/j.bbrc.2012.09.002
https://doi.org/10.1016/j.bbrc.2012.09.002
Autor:
Jeffrey D. Klopfenstein, Dzung H. Dinh, Meena Gujrati, Sravan K. Vanamala, Jasti S. Rao, Daniel Fassett, Krishna Kumar Veeravalli, Chandramu Chetty
Publikováno v:
Cancer Research. 70:511-511
Involvement of MMP-9, cathepsin B and uPAR in glioma adhesion, migration, invasion, proliferation, metastasis and tumor growth has been well studied and reported. In the present study, we have downregulated MMP-9, uPAR and cathepsin B genes by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a97c716a4193c1c20643aa046a4df5
https://doi.org/10.1158/1538-7445.am10-511
https://doi.org/10.1158/1538-7445.am10-511