Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sravan K. Vanamala"'
Autor:
Praveen Bhoopathi, Chandramu Chetty, Sateesh Kunigal, Sravan K. Vanamala, Jasti S. Rao, Sajani S. Lakka
Publikováno v:
The Journal of biological chemistry. 295(45)
We previously showed that MMP-9 inhibition using an adenoviral-mediated delivery of MMP-9 siRNA (Ad-MMP-9), caused senescence in medulloblastoma cells. Regardless of whether or not, Ad-MMP-9 would induce apoptosis, the possible signaling mechanism is
Autor:
Meena Gujrati, Dzung H. Dinh, Chandramu Chetty, Sravan K. Vanamala, Jasti S. Rao, Christopher S. Gondi
Publikováno v:
Cell Signal
CD44 is implicated in cell-cell and cell-matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic potential in various cancers. In this study, we demonstrate that matrix metalloproteinase-9 (MMP-9)
Autor:
Chandramu Chetty, Christopher S. Gondi, Jasti S. Rao, Meena Gujrati, Dzung H. Dinh, Sravan K. Vanamala
Publikováno v:
Cellular Signalling. 24:549-559
CD44 is implicated in cell-cell and cell-matrix adhesion, cell migration, and signaling. CD44 cleavage correlates with the tumor burden and metastatic potential in various cancers. In this study, we demonstrate that matrix metalloproteinase-9 (MMP-9)
Publikováno v:
Biochemical and Biophysical Research Communications. 395:367-372
In the present study, we investigated the cardiomyogenic potential of human umbilical cord blood (hUCB)-derived stem cells and whether stem cell treatment repairs the pathological hypertrophy induced by doxorubicin (DOX) in cultured neonatal rat card
Publikováno v:
Free Radical Biology and Medicine. 45:1723-1728
A proposed mechanism for the cardiotoxicity of doxorubicin (DOX) involves apoptosis in cardiomyocytes. In the study described here, we investigated the molecular basis for the differences in DOX-induced toxicity in adult rat cardiomyocytes (ARCM), ne
Autor:
Praveen Bhoopathi, Jasti S. Rao, Sateesh Kunigal, Sajani S. Lakka, Sravan K. Vanamala, Chandramu Chetty
Publikováno v:
J Biol Chem
We previously showed that matrix metalloproteinase (MMP)-9 inhibition using an adenovirus-mediated delivery of MMP-9 small interfering RNA (Ad-MMP-9), caused senescence in medulloblastoma cells. Regardless of whether or not Ad-MMP-9 would induce apop
Autor:
Shasi V. Kalivendi, Sonya Cunningham, Eugene H. Kaji, Balaraman Kalyanaraman, Eugene A. Konorev, Sravan K. Vanamala, Joy Joseph
Publikováno v:
Biochemical Journal. 389:527-539
Doxorubicin (DOX), a widely used antitumour drug, causes dose-dependent cardiotoxicity. Cardiac mitochondria represent a critical target organelle of toxicity during DOX chemotherapy. Proposed mechanisms include generation of ROS (reactive oxygen spe
Autor:
Jeffrey D. Klopfenstein, Dzung H. Dinh, Jasti S. Rao, Sreelatha Gopinath, Sravan K. Vanamala, Meena Gujrati
Publikováno v:
Cellular and molecular life sciences : CMLS. 66(24)
Nuclear factor of activated T cells (NFAT), a family of transcription factors, has been implicated in many cellular processes, including some cancers. Here, we characterize, for the first time, the role of NFAT3 in doxorubicin (DOX)-mediated apoptosi
Publikováno v:
Biochemical and biophysical research communications. 386(2)
We have assessed the capacity of human umbilical cord blood (hUCB)-derived stem cells to differentiate into cardiomyocytes and repair angiotensin II induced insult in culture and in mouse hearts when injected. hUCB were able to differentiate into car
Publikováno v:
Biochemical and Biophysical Research Communications. 426:668