Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sravan C. Penchala"'
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 4:237-254
Background: The importance of transporters in drug disposition and response has led to increasing interest in genetic variations and expression differences of their genes. Objective: This review summarizes: i) genetic variations in transporters and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb1878b234525b2f46f61504aa8cdd0
https://doi.org/10.1517/17425255.4.3.237
https://doi.org/10.1517/17425255.4.3.237
Autor:
Jinghang Xie, Trevor Cox, Patrick Batoon, Mark Miller, Sravan C. Penchala, Hyun Joo, William K. Chan, Andreas H. Franz, Miki S. Park, Arindom Pal, Mamoun M. Alhamadsheh, Vyacheslav V. Samoshin, Jin Dong, Jesse Miles, Jerry Tsai, Nikhil R. Madadi
Publikováno v:
Nature chemical biology. 11(10)
The tremendous therapeutic potential of peptides has not yet been realized, mainly owing to their short in vivo half-life. Although conjugation to macromolecules has been a mainstay approach for enhancing protein half-life, the steric hindrance of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cd51b0b1a4cf1c24a4b0c03b24a337
https://pubmed.ncbi.nlm.nih.gov/26471364
https://pubmed.ncbi.nlm.nih.gov/26471364
Autor:
Michaela Liedtke, Stephen Connelly, Aleksandra Baranczak, Mamoun M. Alhamadsheh, Jeffery W. Kelly, Natàlia Reixach, Evan T. Powers, Sravan C. Penchala, William K. Chan, Isabella A. Graef, Irit Rappley, Miki S. Park, Ian A. Wilson, Ronald M. Witteles, Hannes Vogel, Yu Wang, Lei Zhao
The misassembly of soluble proteins into toxic aggregates, including amyloid fibrils, underlies a large number of human degenerative diseases. Cardiac amyloidoses, which are most commonly caused by aggregation of Ig light chains or transthyretin (TTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250027824929e7ded602a0e13d3b3d42
https://europepmc.org/articles/PMC3683741/
https://europepmc.org/articles/PMC3683741/
Publikováno v:
Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d12d35f4342ebc69292512410bc1ef
https://doi.org/10.1002/9781118067598.ch21
https://doi.org/10.1002/9781118067598.ch21
Publikováno v:
Current drug discovery technologies. 7(1)
Cancer is the second leading cause of death, for which current therapeutic approaches are still very limited. Chemoprevention is an important approach to decreasing cancer morbidity and mortality by the use of non-toxic natural or synthetic substance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72e1d424d20cf1f3eac3bba6b5e26d7
https://pubmed.ncbi.nlm.nih.gov/20226002
https://pubmed.ncbi.nlm.nih.gov/20226002