Mapping the human genetic architecture of COVID-19

Autor: Niemi, MEK, Karjalainen, J, Liao, RG, Neale, BM, Daly, M, Ganna, A, Pathak, GA, Andrews, SJ, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, EC, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, MA, Wendt, FR, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, MJ, Smith, GD, Willer, CJ, Buxbaum, JD, Mehtonen, J, Finucane, H, Cordioli, M, Martin, AR, Zhou, W, Pasaniuc, B, Julienne, H, Aschard, H, Shi, H, Yengo, L, Polimanti, R, Ghoussaini, M, Schwartzentruber, J, Dunham, I, Chwialkowska, K, Francescatto, M, Trankiem, A, Balaconis, MK, Davis, L, Lee, S, Priest, J, Renieri, A, Sankaran, VG, van Heel, D, Deelen, P, Richards, JB, Nakanishi, T, Biesecker, L, Kerchberger, VE, Kenneth, J, Mari, F, Bernasconi, A, Ceri, S, Canakoglu, A, Wolford, B, Faucon, A, Dutta, AK, Schurmann, C, Harry, E, Birney, E, Nguyen, H, Nasir, J, Kaunisto, M, Solomonson, M, Dueker, N, Vadgama, N, Limou, S, Rahmouni, S, Mbarek, H, Darwish, D, Uddin, MM, Albertos, R, Perez-Tur, J, Li, R, Folkersen, L, Moltke, I, Koelling, N, Teumer, A, Kousathanas, A, Utrilla, A, Verdugo, RA, Zarate, R, Medina-Gomez, C, Gomez-Cabrero, D, Carnero-Montoro, E, Cadilla, CL, Moreno-Estrada, A, Garmendia, A, Moya, L, Sedaghati-Khayat, B, Boua, PR, Fave, M-J, Francioli, L, Lemacon, A, Migeotte, I, Patel, S, Varnai, R, Szentpeteri, JL, Sipeky, C, Colombo, F, von Hohenstaufen, K, Lio, P, Vallerga, C, Wang, Q, Tanigawa, Y, Im, H, Han, C, Song, H, Lim, J, Lee, Y, Kim, S, Im, S, Atanasovska, B, Ahmad, HF, Boer, C, Jansen, P, Franke, L, Kaja, E, Pasko, D, Kennis-Szilagyi, I, Kornilov, SA, Prijatelj, V, Prokic, I, Sivanadhan, I, Perumal, S, Esmaeeli, S, Pearson, NM, Auton, A, Shelton, JF, Shastri, AJ, Filshtein-Sonmez, T, Coker, D, Symons, A, Esparza-Gordillo, J, Aslibekyan, S, O'Connell, J, Ye, C, Weldon, CH, Perera, M, O'Leary, K, Tuck, M, O'Brien, T, Meltzer, D, O'Donnell, P, Nutescu, E, Yang, G, Alarcon, C, Herrmann, S, Mazurek, S, Banagan, J, Hamidi, Z, Barbour, A, Raffat, N, Moreno, D, Friedman, P, Ferwerda, B, van de Beek, D, Brouwer, MC, Vlaar, APJ, Wiersinga, WJ, Posthuma, D, Tissink, E, Zwinderman, AHK, Uffelmann, E, van Agtmael, M, Algera, AG, van Baarle, F, Bax, D, Beudel, M, Bogaard, HJ, Bomers, M, Bonta, PI, Bos, L, Botta, M, de Brabander, J, de Bree, G, de Bruin, S, Bugiani, M, Bulle, E, Chouchane, O, Cloherty, A, Dongelmans, D, Elbers, P, Fleuren, L, Geerlings, S, Geerts, B, Geijtenbeek, T, Girbes, A, Goorhuis, B, Grobusch, MP, Hafkamp, F, Hagens, L, Hamann, J, Harris, V, Hemke, R, Hermans, SM, Heunks, L, Hollmann, M, Horn, J, Hovius, JW, de Jong, MD, Koning, R, van Mourik, N, Nellen, J, Nossent, EJ, Paulus, F, Peters, E, van der Poll, T, Preckel, B, Prins, JM, Raasveld, J, Reijnders, T, Schinkel, M, Schultz, MJ, Schuurman, A, Sigaloff, K, Smit, M, Stijnis, CS, Stilma, W, Teunissen, C, Thoral, P, Tsonas, A, van der Valk, M, Veelo, D, de Vries, H, van Vugt, M, Wouters, D, Minnaar, RP, Kromhout, A, van Uffelen, KWJ, Wolterman, RA, Roberts, G, Park, D, Ball, CA, Coignet, M, McCurdy, S, Knight, S, Partha, R, Rhead, B, Zhang, M, Berkowitz, N, Gaddis, M, Noto, K, Ruiz, L, Pavlovic, M, Hong, EL, Rand, K, Girshick, A, Guturu, H, Baltzell, AH, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J-C, Georges, M, Moutschen, M, Misset, B, Darcis, G, Guiot, J, Jadot, L, Azarzar, S, Dellot, P, Gofflot, S, Claassen, S, Bertrand, A, Parzibut, G, Clarinval, M, Moermans, C, Malaise, O, El Kandoussi, K, Thonon, R, Huynen, P, Mesdagh, A, Melo, S, Jacques, N, Di Valentin, E, Giroule, F, Collignon, A, Radermecker, C, Lebrun, M, Peree, H, Latour, S, Barada, O, Sanchez, J, Josse, C, Boujemla, B, Meunier, M, Mariavelle, E, Anania, S, Gazon, H, Juszczak, D, Fadeur, M, Camby, S, Meuris, C, Thys, M, Jacques, J, Henket, M, Leonard, P, Frippiat, F, Giot, J-B, Sauvage, A-S, Von Frenckell, C, Mni, M, Wery, M, Staderoli, A, Belhaj, Y, Lambermont, B, Morrison, DR, Mooser, V, Forgetta, V, Ghosh, B, Laurent, L, Belisle, A, Henry, D, Abdullah, T, Adeleye, O, Mamlouk, N, Kimchi, N, Afrasiabi, Z, Rezk, N, Vulesevic, B, Bouab, M, Guzman, C, Petitjean, L, Tselios, C, Xue, X, Afilalo, J, Afilalo, M, Oliveira, M, Brenner, B, Brassard, N, Durand, M, Schurr, E, Lepage, P, Ragoussis, J, Auld, D, Chasse, M, Kaufmann, DE, Lathrop, GM, Adra, D, Davis, LK, Cox, NJ, Below, JE, Sealock, JM, Faucon, AB, Shuey, MM, Polikowsky, HG, Petty, LE, Shaw, DM, Chen, H-H, Zhu, W, Ludwig, KU, Schroeder, J, Maj, C, Rolker, S, Noethen, MM, Fazaal, J, Keitel, V, Jensen, B-EO, Feldt, T, Kurth, I, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Augustin, M, Rybniker, J, Knopp, L, Eggermann, T, Volland, S, Altmueller, J, Berger, MM, Brenner, T, Hinney, A, Witzke, O, Bals, R, Herr, C, Ludwig, N, Walter, J, Fuchsberger, C, Pattaro, C, De Grandi, A, Pramstaller, P, Emmert, D, Melotti, R, Foco, L, Mascalzoni, D, Gogele, M, Domingues, F, Hicks, A, Gignoux, CR, Wicks, SJ, Crooks, K, Barnes, KC, Daya, M, Shortt, J, Rafaels, N, Chavan, S, Goldstein, DB, Kiryluk, K, Sengupta, S, Chung, W, Reilly, MP, Khan, A, Wang, C, Povysil, G, Bhardwaj, N, Gharavi, AG, Ionita-Laza, I, Shang, N, O'Byrne, SM, Nandakumar, R, Menon, A, So, YS, Hod, E, Pendrick, D, Park, S-K, Kim, H-L, Kang, CK, Lee, H-J, Song, K-H, Yoon, KJ, Paik, N-J, Seok, W, Yoon, H, Joo, E-J, Chang, Y, Ryu, S, Park, WB, Park, JS, Park, KU, Ham, SY, Jung, J, Kim, ES, Kim, HB, Ellinghaus, D, Degenhardt, F, Caceres, M, Juzenas, S, Lenz, TL, Albillos, A, Julia, A, Heidecker, B, Garcia, F, Kurth, F, Tran, F, Hanses, F, Zoller, H, Holter, JC, Fernandez, J, Sander, LE, Rosenstiel, P, Koehler, P, de Cid, R, Asselta, R, Schreiber, S, Hehr, U, Prati, D, Baselli, G, Valenti, L, Bujanda, L, Banales, JM, Duga, S, D'Amato, M, Romero-Gomez, M, Buti, M, Invernizzi, P, Franke, A, Hov, JR, Karlsen, TH, Folseraas, T, Maya-Miles, D, Teles, A, Azuure, C, Wacker, EM, Uellendahl-Werth, F, Elabd, H, Arora, J, Lerga-Jaso, J, Wienbrandt, L, Ruehlemann, MC, Wendorff, M, Vadla, MS, Lenning, OB, Oezer, O, Myhre, R, Raychaudhuri, S, Tanck, A, Gassner, C, Hemmrich-Stanisak, G, Kaessens, J, Basso, MEF, Schulzky, M, Wittig, M, Braun, N, Wesse, T, Albrecht, W, Yi, X, Ortiz, AB, Garrido Chercoles, A, Ruiz, A, Mantovani, A, Holten, AR, Mayer, A, Cherubini, A, Protti, A, Aghemo, A, Gerussi, A, Ramirez, A, Braun, A, Barreira, A, Lleo, A, Kildal, AB, Glueck, A, Carreras Nolla, A, Latiano, A, Dyrhol-Riise, AM, Muscatello, A, Voza, A, Rando-Segura, A, Solier, A, Karina, B, Cortes, B, Mateos, B, Nafria-Jimenez, B, Schaefer, B, Bellinghausen, C, Ferrando, C, Quereda, C, Skurk, C, Thibeault, C, Spinner, CD, Lange, C, Hu, C, Cappadona, C, Bianco, C, Sancho, C, Hoff, DAL, Galimberti, D, Jimenez, D, Pestana, D, Toapanta, D, Azzolini, E, Scarpini, E, Helbig, ET, Urrechaga, E, Paraboschi, EM, Pontali, E, Reverter, E, Navas, E, Arana, E, Garcia Sanchez, F, Ceriotti, F, Malvestiti, F, Mesonero, F, Pezzoli, G, Lamorte, G, Neb, H, My, I, Hernandez, I, de Rojas, I, Galvan-Femenia, I, Heyckendorf, J, Badia, JR, Schneider, J, Goikoetxea, J, Kraft, J, Mueller, KE, Gaede, KI, Garcia-Etxebarria, K, Tonby, K, Heggelund, L, Izquierdo-Sanchez, L, Sumoy, L, Lippert, LJ, Terranova, L, Garbarino, L, Tellez, L, Roade, L, Ostadreza, M, Intxausti, M, Kogevinas, M, Gutierrez-Stampa, MA, Vehreschild, MJGT, Marquie, M, Castoldi, M, Cecconi, M, Boada, M, Seilmaier, MJ, Mazzocco, M, Rodriguez-Gandia, M, Imaz Ayo, N, Blay, N, Martinez, N, Cornely, OA, Palmieri, O, Tentorio, P, Rodrigues, PM, Espana, PP, Hoffmann, P, Bacher, P, Suwalski, P, de Pablo, R, Nieto, R, Badalamenti, S, Ciesek, S, Bombace, S, Wilfling, S, Brunak, S, Heilmann-Heimbach, S, Ripke, S, Bahmer, T, Landmesser, U, Protzer, U, Rimoldi, V, Skogen, V, Andrade, V, Moreno, V, Poller, W, Farre, X, Wang, X, Khodamoradi, Y, Karadeniz, Z, de Salazar, A, Palom, A, Garcia-Fernandez, A-E, Blanco-Grau, A, Zanella, A, Bandera, A, Nebel, A, Biondi, A, Caba Llero-Garralda, A, Gori, A, Lind, A, Fracanzani, AL, Peschuck, A, Pesenti, A, De la Horra, C, Milani, C, Paccapelo, C, Angelini, C, Cea, C, Muniz-Diaz, E, Sandoval, E, Calderon, EJ, Solligard, E, Aziz, F, Martinelli-Boneschi, F, Peyvandi, F, Blasi, F, Medrano, FJ, Rodriguez-Frias, F, Mueller, F, Grasselli, G, Costantino, G, Cardamone, G, Foti, G, Matullo, G, Kurihara, H, Afset, JE, Damas, JK, Ampuero, J, Martin, J, Erdmann, J, Bergan, J, Goerg, S, Ferrusquia-Acosta, J, Hernandez Quero, J, Delgado, J, Guerrero, JM, Risnes, K, Bettini, LR, Moreira, L, Gustad, LT, Santoro, L, Scudeller, L, Riveiro-Barciela, M, Schaefer, M, Carrabba, M, Valsecchi, MG, Hernandez-Tejero, M, Acosta-Herrera, M, D'Angio, M, Baldini, M, Cazzaniga, M, Ciccarelli, M, Bocciolone, M, Miozzo, M, Chueca, N, Montano, N, Faverio, P, Preatoni, P, Bonfanti, P, Omodei, P, Castro, P, Ferrer, R, Gualtierotti, R, Gallego-Duran, R, Morilla, R, Haider, S, Marsal, S, Aneli, S, Pelusi, S, Bosari, S, Aliberti, S, Dudman, S, Zheng, T, Pumarola, T, Gonzalez Cejudo, T, Monzani, V, Friaza, V, Peter, W, Dopazo, X, May, S, Grimsrud, MM, Gudbjartsson, DF, Stefansson, K, Sulem, P, Sveinbjornsson, G, Melsted, P, Norddahl, G, Moore, KHS, Thorsteinsdottir, U, Holm, H, Alarcon-Riquelme, ME, Bernardo, D, Martinez-Bueno, M, Rojo Rello, S, Magi, R, Milani, L, Metspalu, A, Laisk, T, Lall, K, Lepamets, M, Esko, T, Reimann, E, Naaber, P, Laane, E, Pesukova, J, Peterson, P, Kisand, K, Tabri, J, Allos, R, Hensen, K, Starkopf, J, Ringmets, I, Tamm, A, Kallaste, A, Alavere, H, Metsalu, K, Puusepp, M, Kristiansson, K, Koskelainen, S, Perola, M, Donner, K, Kivinen, K, Palotie, A, Rivolta, C, Bochud, P-Y, Bibert, S, Boillat, N, Nussle, SG, Albrich, W, Quinodoz, M, Kamdar, D, Suh, N, Neofytos, D, Erard, V, Voide, C, Bochud, PY, Friolet, R, Vollenweider, P, Pagani, JL, Oddo, M, zu Bentrup, FM, Conen, A, Clerc, O, Marchetti, O, Guillet, A, Guyat-Jacques, C, Foucras, S, Rime, M, Chassot, J, Jaquet, M, Viollet, RM, Lannepoudenx, Y, Portopena, L, Desgranges, F, Filippidis, P, Guery, B, Haefliger, D, Kampouri, EE, Manuel, O, Munting, A, Iou-Olivgeris, MP, Regina, J, Rochat-Stettler, L, Suttels, V, Tadini, E, Tschopp, J, Van Singer, M, Viala, B, Boillat-Blanco, N, Brahier, T, Hugli, O, Meuwly, JY, Pantet, O, Bochud, M, D'Acremont, V, Younes, SE, Albrich, WC, Cerny, A, O'Mahony, L, von Mering, C, Frischknecht, M, Kleger, G-R, Filipovic, M, Kahlert, CR, Wozniak, H, Negro, TR, Pugin, J, Bouras, K, Knapp, C, Egger, T, Perret, A, Montillier, P, di Bartolomeo, C, Barda, B, Carreras, A, Mercader, JM, Guindo-Martinez, M, Torrents, D, Garcia-Aymerich, J, Castano-Vinyals, G, Dobano, C, Gori, M, Mondelli, MU, Castelli, F, Vaghi, M, Rusconi, S, Montagnani, F, Bargagli, E, Franchi, F, Mazzei, MA, Cantarini, L, Tacconi, D, Feri, M, Scala, R, Spargi, G, Nencioni, C, Bandini, M, Caldarelli, GP, Spagnesi, M, Canaccini, A, Ognibene, A, Monforte, AD, Girardis, M, Antinori, A, Francisci, D, Schiaroli, E, Scotton, PG, Panese, S, Scaggiante, R, Della Monica, M, Capasso, M, Fiorentino, G, Castori, M, Aucella, F, Di Biagio, A, Masucci, L, Valente, S, Mandala, M, Zucchi, P, Giannattasio, F, Coviello, DA, Mussini, C, Bosio, G, Tavecchia, L, Crotti, L, Rizzi, M, La Rovere, MT, Sarzi-Braga, S, Bussotti, M, Ravaglia, S, Artuso, R, Perrella, A, Romani, D, Bergomi, P, Catena, E, Vincenti, A, Ferri, C, Grassi, D, Pessina, G, Tumbarello, M, Di Pietro, M, Sabrina, R, Luchi, S, Barbieri, C, Acquilini, D, Andreucci, E, Paciosi, F, Segala, FV, Tiseo, G, Falcone, M, Lista, M, Poscente, M, De Vivo, O, Petrocelli, P, Guarnaccia, A, Baroni, S, Perticaroli, V, Furini, S, Dei, S, Benetti, E, Picchiotti, N, Sanarico, M, Pinoli, P, Raimondi, F, Biscarini, F, Stella, A, Bergomi, M, Zguro, K, Capitani, K, Tanfoni, M, Fallerini, C, Daga, S, Baldassarri, M, Fava, F, Frullanti, E, Valentino, F, Doddato, G, Giliberti, A, Tita, R, Amitrano, S, Bruttini, M, Croci, S, Meloni, I, Mencarelli, MA, Lo Rizzo, C, Pinto, AM, Beligni, G, Tommasi, A, Di Sarno, L, Palmieri, M, Carriero, ML, Alaverdian, D, Iuso, N, Inchingolo, G, Busani, S, Bruno, R, Vecchia, M, Belli, MA, Mantovani, S, Ludovisi, S, Quiros-Roldan, E, Antoni, MD, Zanella, I, Siano, M, Emiliozzi, A, Fabbiani, M, Rossetti, B, Zanelli, G, Bergantini, L, D'Alessandro, M, Cameli, P, Bennet, D, Anedda, F, Marcantonio, S, Scolletta, S, Guerrini, S, Conticini, E, Frediani, B, Spertilli, C, Donati, A, Guidelli, L, Corridi, M, Croci, L, Piacentini, P, Desanctis, E, Cappelli, S, Verzuri, A, Anemoli, V, Pancrazi, A, Lorubbio, M, Merlini, E, Miraglia, FG, Venturelli, S, Cossarizza, A, Vergori, A, Gabrieli, A, Riva, A, Andretta, F, Gatti, F, Parisi, SG, Baratti, S, Piscopo, C, Russo, R, Andolfo, I, Iolascon, A, Carella, M, Merla, G, Squeo, GM, Raggi, P, Marciano, C, Perna, R, Bassetti, M, Sanguinetti, M, Giorli, A, Salerni, L, Parravicini, P, Menatti, E, Trotta, T, Coiro, G, Lena, F, Martinelli, E, Mancarella, S, Gabbi, C, Maggiolo, F, Ripamonti, D, Bachetti, T, Suardi, C, Parati, G, Botta, G, Di Domenico, P, Rancan, I, Bianchi, F, Colombo, R, van Heel, DA, Hunt, KA, Trembath, RC, Huang, QQ, Martin, HC, Mason, D, Trivedi, B, Wright, J, Finer, S, Griffiths, CJ, Akhtar, S, Anwar, M, Arciero, E, Ashraf, S, Breen, G, Chung, R, Curtis, CJ, Chowdhury, M, Colligan, G, Deloukas, P, Durham, C, Griffiths, C, Hurles, M, Hussain, S, Islam, K, Lavery, C, Lee, SH, Lerner, R, MacArthur, D, MacLaughlin, B, Martin, H, Miah, S, Newman, B, Safa, N, Tahmasebi, F, Smith, AV, Boughton, AP, Li, KW, LeFaive, J, Annis, A, Jannes, CE, Krieger, JE, Pereira, AC, Velho, M, Marques, E, Lima, IR, Tada, MT, Valino, K, McCarthy, M, Rosenberger, C, Lee, JE, Chang, D, Hammer, C, Hunkapiller, J, Mahajan, A, Pendergrass, S, Sucheston-Campbell, L, Yaspan, B, Lee, HS, Shin, E, Jang, HY, Kym, S, Kim, Y-S, Jeong, H, Kwon, KT, Kim, S-W, Kim, JY, Jang, YR, Kim, HA, Lee, JY, Choe, K-W, Kang, YM, Jee, SH, Jung, KJ, Parikh, V, Ashley, E, Wheeler, M, Rivas, M, Bustamante, C, Pinksy, B, Febbo, P, Farh, K, Schroth, GP, deSouza, F, Dalton, K, Christle, J, Deboever, C, Szalma, S, Rubinacci, S, Delaneau, O, Gorzynski, J, de Jong, H, Sutton, S, Youlton, N, Joshi, R, Jimenez-Morales, D, Hughes, C, Amar, D, Ioannidis, A, Hershman, S, Kirillova, A, Seo, K, Huang, Y, Shoura, M, Hammond, N, Watson, N, Raja, A, Huang, C, Sahoo, M, Wang, H, Zhen, J, Rakitko, A, Ilinsky, V, Yermakovich, D, Popov, I, Chernitsov, A, Kovalenko, E, Krasnenko, A, Plotnikov, N, Stetsenko, I, Kim, A, Cirulli, ET, Barrett, KMS, Bolze, A, White, S, Washington, NL, Lu, JT, Riffle, S, Tanudjaja, F, III, RJM, Leonetti, N, Neveux, I, Dabe, S, Grzymski, JJ, Minano, JIE, Aguirre, LA, Lopez-Collazo, E, Pazos, MDLM, Cerrato, L, Lozano-Rodriguez, R, Avendano-Ortiz, J, Terron Arcos, V, Marina Montalban-Hernandez, K, Valentin Quiroga, J, Pascual-Iglesias, A, Maroun-Eid, C, Martin-Quiros, A, Namkoong, H, Imoto, S, Katayama, K, Fukunaga, K, Kitagawa, Y, Sato, T, Hasegawa, N, Kumanogoh, A, Kimura, A, Ai, M, Tokunaga, K, Kanai, T, Miyano, S, Ogawa, S, Edahiro, R, Sonehara, K, Shirai, Y, Ishii, M, Kabata, H, Masaki, K, Kamata, H, Ikemura, S, Chubachi, S, Okamori, S, Terai, H, Tanaka, H, Morita, A, Lee, H, Asakura, T, Sasaki, J, Morisaki, H, Uwamino, Y, Nanki, K, Mikami, Y, Tomono, K, Kato, K, Matsuda, F, Takahashi, M, Hizawa, N, Takeda, Y, Hirata, H, Shiroyama, T, Miyawaki, S, Suzuki, K, Maeda, Y, Nii, T, Noda, Y, Niitsu, T, Adachi, Y, Enomoto, T, Amiya, S, Hara, R, Takahashi, K, Anzai, T, Hasegawa, T, Ito, S, Koike, R, Endo, A, Uchimura, Y, Miyazaki, Y, Honda, T, Tateishi, T, Tohda, S, Ichimura, N, Sonobe, K, Sassa, C, Nakajima, J, Nannya, Y, Omae, Y, Harada, N, Hiki, M, Takagi, H, Nakamura, A, Tagaya, E, Kawana, M, Arimura, K, Ishiguro, T, Takayanagi, N, Isono, T, Takaku, Y, Takano, K, Anan, R, Nakajima, Y, Nakano, Y, Nishio, K, Ueda, S, Hayashi, R, Tateno, H, Hase, I, Yoshida, S, Suzuki, S, Mitamura, K, Saito, F, Ueda, T, Azuma, M, Nagasaki, T, Yasui, Y, Hasegawa, Y, Mutoh, Y, Yoshiyama, T, Shoko, T, Kojima, M, Adachi, T, Ishikawa, M, Watanabe, K, Manabe, T, Ito, F, Fukui, T, Funatsu, Y, Koh, H, Hirai, Y, Kawashima, H, Narita, A, Niwa, K, Sekikawa, Y, Yoshiya, K, Yoshihara, T, Suzuki, Y, Nakayama, S, Masuzawa, K, Nishi, K, Nishitsuji, M, Tani, M, Inoue, T, Hirano, T, Kobayashi, K, Miyazawa, N, Kimura, Y, Sado, R, Ogura, T, Kitamura, H, Murohashi, K, Nakachi, I, Baba, R, Arai, D, Fuke, S, Saito, H, Kuwahara, N, Fujiwara, A, Okada, T, Baba, T, Noda, J, Mashimo, S, Yagi, K, Shiomi, T, Hashiguchi, M, Odani, T, Mochimaru, T, Oyamada, Y, Mori, N, Izumi, N, Nagata, K, Taki, R, Murakami, K, Yamada, M, Sugiura, H, Hayashi, K, Shimizu, T, Gon, Y, Fujitani, S, Tsuchida, T, Yoshida, T, Kagaya, T, Kita, T, Sakagami, S, Kimizuka, Y, Kawana, A, Nakamura, Y, Ishikura, H, Takata, T, Kikuchi, T, Taniyama, D, Nakamura, M, Kodama, N, Kaneyama, Y, Maeda, S, Nagasaki, Y, Okamoto, M, Ishihara, S, Ito, A, Chihara, Y, Takeuchi, M, Onoi, K, Hashimoto, N, Wakahara, K, Ando, A, Masuda, M, Wakabayashi, A, Watanabe, H, Sageshima, H, Nakada, T-A, Abe, R, Shimada, T, Kawamura, K, Ichikado, K, Nishiyama, K, Yamasaki, M, Hashimoto, S, Kusaka, Y, Ohba, T, Isogai, S, Takada, M, Kanda, H, Komase, Y, Sano, F, Asano, K, Oguma, T, Harada, M, Takahashi, T, Shibusawa, T, Abe, S, Kono, Y, Togashi, Y, Izumo, T, Inomata, M, Awano, N, Ogata, T, Kanehiro, A, Ozaki, S, Fuchimoto, Y, Ogura, S, Yoshida, K, Beppu, S, Fukuyama, S, Eriguchi, Y, Yonekawa, A, Inoue, Y, Yamagata, K, Chiba, S, Narumoto, O, Nagai, H, Ooshima, N, Motegi, M, Sagara, H, Tanaka, A, Ohta, S, Shibata, Y, Tanino, Y, Sato, Y, Yamada, Y, Hashino, T, Shinoki, M, Iwagoe, H, Imamura, T, Umeda, A, Shimada, H, Endo, M, Hayashi, S, Nakano, S, Yatomi, M, Maeno, T, Ishii, T, Utsugi, M, Ono, A, Kanaoka, K, Ihara, S, Komuta, K, Boezen, M, Claringbould, A, Lopera, E, Warmerdam, R, Vonk, JM, van Blokland, I, Lanting, P, Ori, APS, Obeidat, M, Cordero, AIH, Sin, DD, Bosse, Y, Joubert, P, Hao, K, Nickle, D, Timens, W, van den Berge, M, Feng, Y-CA, Mercader, J, Weiss, ST, Karlson, EW, Smoller, JW, Murphy, SN, Meigs, JB, Woolley, AE, Green, RC, Perez, EF, Zollner, S, Wang, J, Beck, A, Sloofman, LG, Ascolillo, S, Sebra, RP, Collins, BL, Levy, T, Sealfon, SC, Jordan, DM, Thompson, RC, Gettler, K, Chaudhary, K, Belbin, GM, Preuss, M, Hoggart, C, Choi, S, Underwood, SJ, Salib, I, Britvan, B, Keller, K, Tang, L, Peruggia, M, Hiester, LL, Niblo, K, Aksentijevich, A, Labkowsky, A, Karp, A, Zlatopolsky, M, Zyndorf, M, Charney, AW, Beckmann, ND, Schadt, EE, Abul-Husn, NS, Cho, JH, Itan, Y, Kenny, EE, Loos, RJF, Nadkarni, GN, Do, R, O'Reilly, P, Huckins, LM, Ferreira, MAR, Abecasis, GR, Leader, JB, Cantor, MN, Justice, AE, Carey, DJ, Chittoor, G, Josyula, NS, Kosmicki, JA, Horowitz, JE, Baras, A, Gass, MC, Yadav, A, Mirshahi, T, Hottenga, JJ, Bartels, M, de Geus, EJC, Nivard, MG, Verma, A, Ritchie, MD, Rader, D, Li, B, Verma, SS, Lucas, A, Bradford, Y, Zara, F, Salpietro, V, Scala, M, Iacomino, M, Scudieri, P, Bocciardi, R, Minetti, C, Vari, MS, Rahier, J-F, Giorgio, E, Carli, D, Louis, E, Bulik, CM, Landen, M, Brusco, A, Ferrero, GB, Madia, F, Fundin, B, Ismail, SI, Saad, C, Al-Sarraj, Y, Badji, RM, Al-Muftah, W, Al Thani, A, Afifi, N, Klovins, J, Rovite, V, Rescenko, R, Peculis, R, Ustinova, M, Zeberg, H, Frithiof, R, Hultstrom, M, Lipcsey, M, Johnson, R, Geschwind, DH, Freimer, N, Butte, MJ, Ding, Y, Chiu, A, Chang, TS, Boutros, P, Moutsianas, L, Caulfield, MJ, Scott, RH, Walker, S, Stuckey, A, Odhams, CA, Rhodes, D, Fowler, T, Rendon, A, Chan, G, Arumugam, P, Karczewski, KJ, Wilson, DJ, Spencer, CA, Crook, DW, Wyllie, DH, O'Connell, AM, Atkinson, EG, Tsuo, K, Baya, N, Turley, P, Gupta, R, Walters, RK, Palmer, DS, Sarma, G, Cheng, N, Lu, W, Churchhouse, C, Goldstein, JI, King, D, Seed, C, Daly, MJ, Bryant, S, Satterstrom, FK, Band, G, Earle, SG, Lin, S-K, Arning, N, Armstrong, J, Rudkin, JK, Callier, S, Cusick, C, Soranzo, N, Zhao, JH, Danesh, J, Di Angelantonio, E, Butterworth, AS, Sun, YV, Huffman, JE, Cho, K, O'Donnell, CJ, Tsao, P, Gaziano, JM, Peloso, G, Ho, Y-L, Mian, M, Scaggiante, F, Chang, X, Glessner, JR, Hakonarson, H, Baillie, JK, McGuigan, PJ, Moore, LSP, Vizcaychipi, MP, Hall, K, Campbell, A, Nichol, A, Ward, G, Page, VJ, Semple, MG, Adeniji, K, Agranoff, D, Agwuh, K, Ail, D, Aldera, EL, Alegria, A, Angus, B, Ashish, A, Atkinson, D, Bari, S, Barlow, G, Barnass, S, Barrett, N, Bassford, C, Basude, S, Baxter, D, Beadsworth, M, Bernatoniene, J, Berridge, J, Best, N, Bothma, P, Chadwick, D, Brittain-Long, R, Bulteel, N, Burden, T, Burtenshaw, A, Caruth, V, Chambler, D, Chee, N, Child, J, Chukkambotla, S, Clark, T, Collini, P, Cosgrove, C, Cupitt, J, Cutino-Moguel, M-T, Dark, P, Dawson, C, Dervisevic, S, Donnison, P, Douthwaite, S, Drummond, A, DuRand, I, Dushianthan, A, Dyer, T, Evans, C, Eziefula, C, Fegan, C, Finn, A, Fullerton, D, Garg, S, Garg, A, Gkrania-Klotsas, E, Godden, J, Goldsmith, A, Graham, C, Hardy, E, Hartshorn, S, Harvey, D, Havalda, P, Hawcutt, DB, Hobrok, M, Hodgson, L, Hormis, A, Jacobs, M, Jain, S, Jennings, P, Kaliappan, A, Kasipandian, V, Kegg, S, Kelsey, M, Kendall, J, Kerrison, C, Kerslake, I, Koch, O, Koduri, G, Koshy, G, Laha, S, Laird, S, Larkin, S, Leiner, T, Lillie, P, Limb, J, Linnett, V, Little, J, Lyttle, M, MacMahon, M, MacNaughton, E, Mankregod, R, Masson, H, Matovu, E, McCullough, K, McEwen, R, Meda, M, Mills, GH, Minton, J, Ward, K, Mirfenderesky, M, Mohandas, K, Mok, Q, Moon, J, Moore, E, Morgan, P, Morris, C, Mortimore, K, Moses, S, Mpenge, M, Mulla, R, Murphy, M, Nagel, M, Nagarajan, T, Nelson, M, O'Shea, MK, Otahal, I, Ostermann, M, Pais, M, Panchatsharam, S, Papakonstantinou, D, Paraiso, H, Patel, B, Pattison, N, Pepperell, J, Peters, M, Phull, M, Pintus, S, Pooni, JS, Post, F, Price, D, Prout, R, Rae, N, Reschreiter, H, Reynolds, T, Richardson, N, Roberts, M, Roberts, D, Rose, A, Rousseau, G, Ryan, B, Saluja, T, Shah, A, Shanmuga, P, Sharma, A, Shawcross, A, Sizer, J, Shankar-Hari, M, Smith, R, Snelson, C, Spittle, N, Staines, N, Stambach, T, Stewart, R, Subudhi, P, Szakmany, T, Tatham, K, Thomas, J, Thompson, C, Thompson, R, Tridente, A, Tupper-Carey, D, Twagira, M, Ustianowski, A, Vallotton, N, Vincent-Smith, L, Visuvanathan, S, Vuylsteke, A, Waddy, S, Wake, R, Walden, A, Welters, I, Whitehouse, T, Whittaker, P, Whittington, A, Papineni, P, Wijesinghe, M, Williams, M, Wilson, L, Cole, S, Winchester, S, Wiselka, M, Wolverson, A, Wooton, DG, Workman, A, Yates, B, Young, P, Beale, R, Bretherick, AD, Clohisey, S, Fourman, MH, Furniss, J, Gountouna, E, Grimes, G, Haley, C, Harrison, D, Hayward, C, Keating, S, Klaric, L, Klenerman, P, Law, A, Meynert, AM, Millar, J, Pairo-Castineira, E, Parkinson, N, Ponting, CP, Porteous, DJ, Rawlik, K, Richmond, A, Rowan, K, Russell, CD, Shen, X, Shih, B, Tenesa, A, Vitart, V, Wang, B, Wilson, JF, Wu, Y, Yang, J, Yang, Z, Zechner, M, Zhai, R, Zheng, C, Norman, L, Pius, R, Drake, TM, Fairfield, CJ, Knight, SR, Mclean, KA, Murphy, D, Shaw, CA, Dalton, J, Girvan, M, Saviciute, E, Roberts, S, Harrison, J, Marsh, L, Connor, M, Halpin, S, Jackson, C, Gamble, C, Leeming, G, Wham, M, Hendry, R, Scott-Brown, J, Begg, C, Hinds, C, Ho, AYW, Horby, PW, Knight, J, Ling, L, Maslove, D, McAuley, D, Montgomery, H, Openshaw, PJM, Summers, C, Walsh, T, Armstrong, L, Bates, H, Dooks, E, Farquhar, F, Hairsine, B, McParland, C, Packham, S, Alldis, Z, Lain, RA-C, Bibi, F, Biddle, J, Blow, S, Bolton, M, Borra, C, Bowles, R, Burton, M, Choudhury, Y, Collier, D, Cox, A, Easthope, A, Ebano, P, Fotiadis, S, Gurasashvili, J, Halls, R, Hartridge, P, Kallon, D, Kassam, J, Lancoma-Malcolm, I, Matharu, M, May, P, Mitchelmore, O, Newman, T, Patel, M, Pheby, J, Pinzuti, I, Prime, Z, Prysyazhna, O, Shiel, J, Taylor, M, Tierney, C, Wood, S, Zak, A, Zongo, O, Forsey, M, Nicholson, A, Riches, J, Vertue, M, Wasson, C, Finn, S, Green, J, Collins, E, King, B, Grauslyte, L, Hussain, M, Pogreban, T, Rosaroso, L, Salciute, E, Franke, G, Wong, J, George, A, Akeroyd, L, Bano, S, Bromley, M, Gurr, L, Lawton, T, Morgan, J, Sellick, K, Warren, D, Wilkinson, B, McGowan, J, Ledgard, C, Stacey, A, Pye, K, Bellwood, R, Bentley, M, Loosley, R, McGuinness, H, Tench, H, Wolf-Roberts, R, Gibson, S, Lyle, A, McNeela, F, Radhakrishnan, J, Hughes, A, Ali, A, Brady, M, Dale, S, Dance, A, Gledhill, L, Greig, J, Hanson, K, Holdroyd, K, Home, M, Kelly, D, Kitson, R, Matapure, L, Melia, D, Mellor, S, Nortcliffe, T, Pinnell, J, Robinson, M, Shaw, L, Shaw, R, Thomis, L, Wilson, A, Wood, T, Bayo, L-A, Merwaha, E, Ishaq, T, Hanley, S, Antcliffe, D, Banach, D, Brett, S, Coghlan, P, Fernandez, Z, Gordon, A, Rojo, R, Arias, SS, Templeton, M, Jha, R, Krishnamurthy, V, Lim, L, Bi, R, Scholefield, B, Ashton, L, Williams, A, Cheyne, C, Saunderson, A, Allan, A, Anderson, F, Kaye, C, Liew, J, Medhora, J, Scott, T, Trumper, E, Botello, A, Polgarova, P, Stroud, K, Meaney, E, Jones, M, Ng, A, Agrawal, S, Pathan, N, White, D, Daubney, E, Elston, K, Parker, R, Reddy, A, Turner-Bone, I, Wilding, L, Harding, P, Jacob, R, Jones, C, Denmade, C, Croft, M, White, I, Griffin, D, Muchenje, N, Mupudzi, M, Partridge, R, Conyngham, J-A, Thomas, R, Wright, M, Corral, MA, Bastion, V, Clarke, D, David, B, Kent, H, Lorusso, R, Lubimbi, G, Murdoch, S, Penacerrada, M, Thomas, A, Valentine, J, Vochin, A, Wulandari, R, Djeugam, B, Dawson, J, Garrioch, S, Tolson, M, Aldridge, J, Martins, LGDA, Carungcong, J, Beavis, S, Dale, K, Gascoyne, R, Hawes, J, Pritchard, K, Stevenson, L, Whileman, A, Cowley, A, Highgate, J, Crawley, R, Crew, A, Cunningham, M, Daniels, A, Harrison, L, Hope, S, Inweregbu, K, Jones, S, Lancaster, N, Matthews, J, Wray, G, Benham, L, Bradshaw, Z, Brown, J, Caswell, M, Melling, S, Preston, S, Slawson, N, Stoddard, E, Warden, S, Combes, E, Joefield, T, Monnery, S, Beech, V, Trotman, S, Hopkins, B, Scriven, J, Thrasyvoulou, L, Willis, H, Anderson, S, Birch, J, Hammerton, K, O'Leary, R, Abernathy, C, Foster, L, Gratrix, A, Martinson, V, Parkinson, P, Stones, E, Carbral-Ortega, L, Kapoor, R, Loader, D, Castle, K, Brandwood, C, Smith, L, Clark, R, Birchall, K, Kolakaluri, L, Baines, D, Sukumaran, A, Mapfunde, I, Meredith, M, Morris, L, Ryan, L, Clark, A, Sampson, J, Peters, C, Dent, M, Langley, M, Wei, S, Andrew, A, Chablani, M, Kirkby, A, Netherton, K, Bates, M, Dasgin, J, Gill, J, Nilsson, A, Apetri, E, Basikolo, C, Blackledge, B, Catlow, L, Charles, B, Doonan, R, Harris, J, Harvey, A, Horner, D, Knowles, K, Lomas, D, Lyons, C, Marsden, T, McLaughlan, D, McMorrow, L, Pendlebury, J, Perez, J, Poulaka, M, Proudfoot, N, Slaughter, M, Slevin, K, Thomas, V, Walker, D, Michael, A, Collis, M, Clark, M, Coulding, M, Jude, E, McCormick, J, Mercer, O, Potla, D, Rehman, H, Savill, H, Turner, V, Davey, M, Golden, D, Seaman, R, Hunt, J, Dearden, J, Dobson, E, Mulcahy, M, Munt, S, O'Connor, G, Philbin, J, Rishton, C, Tully, R, Winnard, S, Cagova, L, Fofano, A, Garner, L, Holcombe, H, Mepham, S, Mitchell, AM, Mwaura, L, Praman, K, Zamikula, J, Bercades, G, Brealey, D, Hass, I, MacCallum, N, Martir, G, Raith, E, Reyes, A, Smyth, D, Taylor, A, Hughes, RA, Thomas, H, Rees, A, Duskova, M, Phipps, J, Brooks, S, Edwards, M, Alexander, P, Allen, S, Bradley-Potts, J, Brantwood, C, Egan, J, Felton, T, Padden, G, Ward, L, Moss, S, Glasgow, S, Beesley, K, Board, S, Kubisz-Pudelko, A, Lewis, A, Perry, J, Pippard, L, Wood, D, Buckley, C, Brown, A, Gregory, J, O'Connell, S, Smith, T, Belagodu, Z, Fuller, B, Gherman, A, Olufuwa, O, Paramsothy, R, Stuart, C, Oakley, N, Kamundi, C, Tyl, D, Collins, K, Silva, P, Taylor, J, King, L, Coates, C, Crowley, M, Wakefield, P, Beadle, J, Johnson, L, Sargeant, J, Anderson, M, Jardine, C, Williams, D, Parris, V, Quaid, S, Watson, E, Melville, J, Naisbitt, J, Joseph, R, Lazo, M, Walton, O, Neal, A, Hill, M, Kannan, T, Wild, L, Allan, E, Darlington, K, Davies, F, Easton, J, Kumar, S, Lean, R, Menzies, D, Pugh, R, Qiu, X, Davies, L, Williams, H, Scanlon, J, Davies, G, Mackay, C, Lewis, J, Rees, S, Coetzee, S, Gales, A, Raj, M, Sell, C, Langton, H, Watters, M, Novis, C, Arbane, G, Bociek, A, Campos, S, Grau, N, Jones, TO, Lim, R, Marotti, M, Whitton, C, Barron, A, Collins, C, Kaul, S, Passmore, H, Prendergast, C, Reed, A, Rogers, P, Shokkar, R, Woodruff, M, Middleton, H, Polgar, O, Nolan, C, Thwaites, V, Mahay, K, Sri-Chandana, C, Scherewode, J, Stephenson, L, Marsh, S, Bancroft, H, Bellamy, M, Carmody, M, Daglish, J, Moore, F, Rhodes, J, Sangombe, M, Kadiri, S, Ayers, A, Harrison, W, North, J, Cavazza, A, Cockrell, M, Corcoran, E, Depante, M, Finney, C, Jerome, E, McPhail, M, Nayak, M, Noble, H, O'Reilly, K, Pappa, E, Saha, R, Saha, S, Smith, J, Knighton, A, Gill, M, Paul, P, Ratnam, V, Shelton, S, Wynter, I, Baptista, D, Crowe, R, Fernandes, R, Herdman-Grant, R, Joseph, A, Loveridge, A, McKenley, I, Morino, E, Naranjo, A, Simms, R, Sollesta, K, Swain, A, Venkatesh, H, Khera, J, Fox, J, Barber, R, Hewitt, C, Hilldrith, A, Jackson-Lawrence, K, Shepardson, S, Wills, M, Butler, S, Tavares, S, Cunningham, A, Hindale, J, Arif, S, George, L, Twiss, S, Wright, D, Holland, M, Keenan, N, Lyons, M, Wassall, H, Marsh, C, Mahenthran, M, Carter, E, Kong, T, Adanini, O, Bhatia, N, Msiska, M, Mew, L, Mwaura, E, Williams, F, Wren, L, Sutherland, S-B, Battle, C, Brinkworth, E, Harford, R, Murphy, C, Newey, L, Rees, T, Arnold, S, Hardy, J, Houlden, H, Moncur, E, Tariq, A, Tucci, A, Convery, K, Fottrell-Gould, D, Hudig, L, Keshet-Price, J, Randell, G, Stammers, K, Abdelrazik, M, Bakthavatsalam, D, Elhassan, M, Ganesan, A, Haldeos, A, Moreno-Cuesta, J, Purohit, D, Vincent, R, Xavier, K, Rohit, K, Alasdair, F, Saleem, M, David, C, Jenkins, S, Lamond, Z, Wall, A, Reynolds, J, Campbell, H, Thompsom, M, Dodds, S, Duffy, S, Butcher, D, O'Sullivan, S, Butterworth-Cowin, N, Deacon, B, Hibbert, M, Pothecary, C, Tetla, D, Woodford, C, Durga, L, Kennard-Holden, G, de Gordoa, LO-R, Peasgood, E, Phillips, C, Skinner, D, Gaylard, J, Mullan, D, Newman, J, Davies, E, Roche, L, Sathe, S, Brimfield, L, Daly, Z, Pogson, D, Rose, S, Collins, A, Khaliq, W, Gude, ET, Allen, L, Beranova, E, Crisp, N, Deery, J, Hazelton, T, Knight, A, Price, C, Tilbey, S, Turki, S, Turney, S, Giles, J, Booth, S, Bell, G, English, K, Katary, A, Wilcox, L, Campbell, R, Clarke, N, Whiteside, J, Mascarenhas, M, Donaldson, A, Matheson, J, Barrett, F, O'Hara, M, O'Keefe, L, Bradley, C, Walker, R, Maynard, V, Patel, T, Smith, M, Kazi, A, Hartley, J, Dykes, J, Hijazi, M, Keith, S, Khan, M, Ryan-Smith, J, Springle, P, Truman, N, Saad, S, Coleman, D, Fine, C, Matt, R, Gay, B, Dalziel, J, Ali, S, Goodchild, D, Harling, R, Bhatterjee, R, Goddard, W, Davison, C, Duberly, S, Hargreaves, J, Bolton, R, Verlander, M, Blackman, H, Creagh-Brown, B, Donlon, S, Michalak-Glinska, N, Mtuwa, S, Pristopan, V, Salberg, A, Smith, E, Stone, S, Piercy, C, Verula, J, Burda, D, Montaser, R, Harden, L, Mayangao, I, Marriott, C, Bradley, P, Harris, C, Cooper, J, Finch, C, Liderth, S, Quinn, A, Waddington, N, Fidler, K, Tagliavini, E, Donnelly, K, Abel, L, Brett, M, Digby, B, Gemmell, L, Hornsby, J, MacGoey, P, O'Neil, P, Price, R, Rodden, N, Rooney, K, Sundaram, R, Thomson, N, Flanagan, R, Hughes, G, Latham, S, McKenna, E, Anderson, J, Hull, R, Rhead, K, Branney, D, Frankham, J, Pitts, S, White, N, Cristiano, D, Dormand, N, Farzad, Z, Gummadi, M, Liyanage, K, Patel, BV, Salmi, S, Sloane, G, Varghese, M, Zborowski, AC, Bean, S, Burt, K, Spivey, M, Eastgate-Jackson, C, Filipe, H, Martin, D, Maharajh, A, Garcia, SM, De Neef, M, Lynch, C, Howe, GS, Singh, J, Turner, K, Ellis, H, Stroud, N, Cherian, S, Cutler, S, Heron, AE, Roynon-Reed, A, Williams, G, Richards, O, Cheema, Y, Ahmad, N, Barker, J, Bauchmuller, K, Bird, S, Cawthron, K, Harrington, K, Jackson, Y, Kibutu, F, Lenagh, B, Masuko, S, Raithatha, A, Wiles, M, Willson, J, Newell, H, Lye, A, Nwafor, L, Jarman, C, Rowland-Jones, S, Foote, D, Cole, J, Watson, J, Hesseldon, L, Macharia, I, Chetam, L, Ford, A, Housley, K, Milner, L, Hanratty, H, Trower, H, Phillips, P, Oxspring, S, Donne, B, Bevan, E, Trodd, D, Watson, G, Brown, CW, Bunni, L, Jennings, C, Latif, M, Marshall, R, Subramanian, G, Bandla, N, Gellamucho, M, Davies, M, Trim, F, Eapen, B, Ahmed, C, Baines, B, Clamp, S, Colley, J, Haq, R, Hayes, A, Hulme, J, Joseph, S, Kumar, R, Maqsood, Z, Purewal, M, Chandler, B, Elliott, K, Mallinson, J, Turnbull, A, Dent, K, Horsley, E, Akhtar, MN, Pearson, S, Potoczna, D, Spencer, S, Blakemore, H, Borislavova, B, Faulkner, B, Gendall, E, Goff, E, Hayes, K, Thomas, M, Worner, R, Smith, K, Stephens, D, Delgado, CC, Dawson, D, Ding, L, Durrant, G, Ezeobu, O, Farnell-Ward, S, Harrison, A, Kanu, R, Leaver, S, Maccacari, E, Manna, S, Saluzzio, RP, Queiroz, J, Samakomva, T, Sicat, C, Texeira, J, Da Gloria, EF, Lisboa, A, Rawlins, J, Mathew, J, Kinch, A, Hurt, WJ, Shah, N, Clark, V, Thanasi, M, Yun, N, Patel, K, Crickmore, V, Debreceni, G, Wilkins, J, Nicol, L, Burn, I, Hambrook, G, Manso, K, Penn, R, Shanmugasundaram, P, Tebbutt, J, Thornton, D, Rostron, A, Roy, A, Woods, L, Cornell, S, Wakinshaw, F, Rogerson, K, Jarmain, J, Anderson, P, Archer, K, Austin, K, Davis, C, Durie, A, Kelsall, O, Thrush, J, Vigurs, C, Wood, H-L, Tranter, H, Cowley, N, McAlindon, M, Digby, S, Low, E, Morgan, A, Cother, N, Rankin, T, Clayton, S, McCurdy, A, Allibone, S, Mary-Genetu, R, Patel, A, Mac, A, Murphy, A, Mahjoob, P, Nazari, R, Worsley, L, Fagan, A, Ali, IMA, Beaumont, K, Blunt, M, Coton, Z, Curgenven, H, Elsaadany, M, Fernandes, K, Ally, SM, Rangarajan, H, Sarathy, V, Selvanayagam, S, Vedage, D, White, M, Fernandez-Roman, J, Hamilton, DO, Johnson, E, Johnston, B, Martinez, ML, Mulla, S, Shaw, D, Waite, AAC, Waugh, V, Welters, ID, Williams, K, Bemand, T, Black, E, Dela Rosa, A, Howle, R, Jhanji, S, Baikady, RR, Tatham, KC, Thomas, B, Halkes, M, Mercer, P, Thornton, L, West, J, Baird, T, Ruddy, J, Reece-Anthony, R, Birt, M, Cowton, A, Kay, A, Kent, M, Potts, K, Wilkinson, A, Naylor, S, Brown, E, Purvis, S, Davies, R, Duffin, D, Hill, H, Player, B, Thomas, E, Beith, CM, Black, K, Clements, S, Morrison, A, Strachan, D, Clarkson, M, D'Sylva, S, Norman, K, Coventry, T, Fowler, S, McGregor, A, Brady, A, Chan, R, McIvor, S, Prady, H, Whittle, H, Mathew, B, Clapham, M, Harper, R, Poultney, U, Rice, P, Mutch, R, Baird, Y, Butler, A, Chadbourn, I, Folkes, L, Fox, H, Gardner, A, Gomez, R, Hobden, G, King, K, Margarson, M, Martindale, T, Meadows, E, Raynard, D, Thirlwall, Y, Helm, D, Margalef, J, Greer, S, Shuker, K, Smuts, S, Duffield, J, Smith, O, Mallon, L, Claire, W, Birkinshaw, I, Carter, J, Howard, K, Ingham, J, Joy, R, Pearson, H, Roche, S, Scott, Z, Knights, E, Price, A, Thorpe, C, Abraheem, A, Bamford, P, Cawley, K, Dunmore, C, Faulkner, M, Girach, R, Jeffrey, H, Jones, R, London, E, Nagra, I, Nasir, F, Sainsbury, H, Smedley, C, Khade, R, Sundar, A, Tsinaslanidis, G, Behan, T, Burnett, C, Hatton, J, Heeney, E, Mitra, A, Newton, M, Pollard, R, Stead, R, Bough, L, Goodsell, J, Tutton, R, Williams, P, Williams, S, Winter-Goodwin, B, Auld, F, Donnachie, J, Edmond, I, Prentice, L, Runciman, N, Salutous, D, Symon, L, Todd, A, Turner, P, Short, A, Sweeney, L, Murdoch, E, Senaratne, D, Burns, K, Higham, A, Anderson, T, Hawcutt, D, O'Malley, L, Rad, L, Rogers, N, Saunderson, P, Allison, KS, Afolabi, D, Whitbread, J, Jones, D, Dore, R, Lankester, L, Nikitas, N, Wells, C, Stowe, B, Spencer, K, Cathcart, S, Duffy, K, Puxty, A, Puxty, K, Turner, L, Ireland, J, Semple, G, Barry, P, Hilltout, P, Evitts, J, Tyler, A, Waldron, J, Irvine, V, Shelley, B, Akinkugbe, O, Bamford, A, Beech, E, Belfield, H, Bell, M, Davies, C, Jones, GAL, McHugh, T, Meghari, H, O'Neill, L, Peters, MJ, Ray, S, Tomas, AL, Gorman, C, Gupta, A, Timlick, E, Brady, R, Bonner, S, Hugill, K, Jones, J, Liggett, S, Bashyal, A, Davidson, N, Hutton, P, McKechnie, S, Wilson, J, Flint, N, Rekha, P, Hales, D, Cruz, C, Gopal, S, Harris, N, Lake, V, Metherell, S, Radford, E, Clement, I, Gulati, A, Hays, C, Webster, K, Hudson, A, Webster, A, Stephenson, E, McCormack, L, Slater, V, Nixon, R, Hanson, H, Fearby, M, Kelly, S, Bridgett, V, Robinson, P, Almaden-Boyle, C, Austin, P, Cabrelli, L, Casey, M, Chapman, S, Whyte, C, Brayne, A, Fisher, E, Jackson, P, Kaye, D, Love, N, Parkin, J, Tuckey, V, van Koutrik, L, Carter, S, Andrew, B, Findlay, L, Adams, K, Bruce, M, Connolly, K, Duncan, T, Michael, HT, Lindergard, G, Hey, S, Fox, C, Alfonso, J, Durrans, LJ, Guerin, J, Hruska, M, Eltayeb, A, Lamb, T, Hodgkiss, T, Cooper, L, Rothwell, J, Dennis, C, Srikaran, S, Sukha, A, Davies, K, O'Brien, L, Omar, Z, Perkins, E, Lewis, T, Sutherland, I, Brooke, H, Buckley, S, Suarez, JC, Charlesworth, R, Hansson, K, Norris, J, Poole, A, Sandhu, R, Sloan, B, Smithson, E, Thirumaran, M, Wagstaff, V, Metcalfe, A, Camsooksai, J, Humphrey, C, Wadams, B, Death, Y, Adams, C, Agasou, A, Arden, T, Bowes, A, Boyle, P, Beekes, M, Button, H, Capps, N, Carnahan, M, Carter, A, Childs, D, Donaldson, D, Hard, K, Hurford, F, Hussain, Y, Javaid, A, Jose, S, Leigh, M, Martin, T, Millward, H, Motherwell, N, Rikunenko, R, Stickley, J, Summers, J, Ting, L, Tivenan, H, Tonks, L, Wilcox, R, Bokhari, M, Lucas, R, McCormick, W, Ritzema, J, Sanderson, A, Wild, H, Baxter, N, Henderson, S, Kennedy-Hay, S, Rooney, L, Sim, M, McCreath, G, Brunton, M, Caterson, J, Coles, H, Frise, M, Rai, SG, Keating, L, Tilney, E, Bartley, S, Bhuie, P, Downes, C, Holding, K, Riches, K, Hilton, M, Hayman, M, Subramanian, D, Daniel, P, Zitter, L, Benyon, S, Marriott, S, Park, L, Keenan, S, Gordon, E, Quinn, H, Baines, K, Andrew, G, Barclay, L, Callaghan, M, Clark, S, Hope, D, Marshall, L, McCulloch, C, Briton, K, Singleton, J, Birch, S, Simpson, K, Craig, J, Demetriou, C, Eckbad, C, Hierons, S, Howie, L, Mitchard, S, Ramos, L, Serrano-Ruiz, A, White, K, Kelly, F, Amin, V, Anastasescu, E, Anumakonda, V, Karthik, K, Kausar, R, Reid, K, Imeson-Wood, J, Bellini, A, Bryant, J, Pickard, A, Roe, N, Sowter, J, Howlett, A, Criste, K, Cusack, R, Golder, K, Golding, H, Jones, O, Leggett, S, Male, M, Marani, M, Prager, K, Williams, T, Roberts, B, Salmon, K, Gondo, P, Hadebe, B, Kayani, A, Masunda, B, Ahmed, A, Morris, A, Jakkula, S, Long, K, Whiteley, S, Wilby, E, Ogg, B, Moultrie, S, Odam, M, Bewley, J, Garland, Z, Grimmer, L, Gumbrill, B, Sweet, K, Webster, D, Efford, G, Bennett, S, Goodwin, E, Jackson, M, Kent, A, Tibke, C, Woodyatt, W, Zaki, A, Daniel, A, Finn, J, Bremmer, P, Allan, J, Geary, T, Houston, G, Meikle, A, O'Brien, P, Bell, D, Boyle, R, Douglas, K, Glass, L, Lee, E, Lennon, L, Rattray, A, Charnock, R, McFarland, D, Cosgrove, D, Attwood, B, Parsons, P, Carmody, S, Oblak, M, Popescu, M, Thankachen, M, Baruah, R, Morris, S, Ferguson, S, Shepherd, A, Altabaibeh, A, Alvaro, A, Gilbert, K, Ma, L, Mostoles, L, Parmar, C, Jetha, C, Booker, L, Pratley, A, Cosier, T, Millen, G, Schumacher, N, Weston, H, Rand, J, Alex, B, Bach, B, Barclay, WS, Bogaert, D, Chand, M, Cooke, GS, Docherty, AB, Dunning, J, Filipe, ADS, Fletcher, T, Green, CA, Harrison, EM, Hiscox, JA, Ijaz, S, Khoo, S, Lim, WS, Mentzer, AJ, Merson, L, Noursadeghi, M, Moore, SC, Palmarini, M, Paxton, WA, Pollakis, G, Price, N, Rambaut, A, Robertson, DL, Sancho-Shimizu, V, Scott, JT, de Silva, T, Sigfrid, L, Solomon, T, Sriskandan, S, Stuart, D, Tedder, RS, Thomson, EC, Thompson, AAR, Thwaites, RS, Turtle, LCW, Gupta, RK, Palmieri, C, Swann, OV, Zambon, M, Dumas, M-E, Griffin, JL, Takats, Z, Chechi, K, Andrikopoulos, P, Osagie, A, Olanipekun, M, Liggi, S, Lewis, MR, Correia, GDS, Sands, CJ, Takis, P, Maslen, L, Greenhalf, W, Shaw, V, McDonald, SE, Ahmed, KA, Armstrong, JA, Ashworth, M, Asiimwe, IG, Bakshi, S, Barlow, SL, Booth, L, Brennan, B, Bullock, K, Catterall, BWA, Clark, JJ, Clarke, EA, Cox, H, Dincarslan, O, Dunn, C, Dyer, P, Elliott, A, Evans, A, Finch, L, Fisher, LWS, Foster, T, Garcia-Dorival, I, Gunning, P, Hartley, C, Jensen, RL, Jones, CB, Jones, TR, Khandaker, S, Kiy, RT, Koukorava, C, Lake, A, Lant, S, Latawiec, D, Lavelle-Langham, L, Lefteri, D, Lett, L, Livoti, LA, Mancini, M, McDonald, S, McEvoy, L, McLauchlan, J, Metelmann, S, Miah, NS, Middleton, J, Mitchell, J, Murphy, EG, Penrice-Randal, R, Pilgrim, J, Prince, T, Reynolds, W, Ridley, PM, Sales, D, Shaw, VE, Shears, RK, Small, B, Subramaniam, KS, Szemiel, A, Taggart, A, Tanianis-Hughes, J, Trochu, E, van Tonder, L, Wilcock, E, Zhang, JE, Flaherty, L, Maziere, N, Cass, E, Carracedo, AD, Carlucci, N, Holmes, A, Massey, H, Murphy, L, Wrobel, N, McCafferty, S, Morrice, K, MacLean, A, Armstrong, R, Boz, C, Coutts, A, Cullum, L, Day, N, Donnelly, L, Duncan, E, Fawkes, A, Finernan, P, Gilchrist, T, Golightly, A, Hafezi, K, Law, D, Law, R, Law, S, Macgillivray, L, Maclean, A, Mal, H, Mcmaster, E, Meikle, J, Oosthuyzen, W, Paterson, T, Stenhouse, A, Swets, M, Szoor-McElhinney, H, Taneski, F, Wackett, T, Ward, M, Weaver, J, Coyle, J, Gallagher, B, Lidstone-Scott, R, Hamilton, D, Schon, K, Furlong, A, Biggs, H, Griffiths, F, Andrews, E, Brickell, K, Smyth, M, Carson, G, Hardwick, H, Donohue, C, Initiative, CHG, Team, AC, Grp, NS-CS, Force, HCT, Task, HGC, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Team, GHR, Working, UCLAHATLASDM

Publikováno v: NATURE
Initiative, COVID H G & Dark, P 2021, ' Mapping the human genetic architecture of COVID-19. ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
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Nature, vol 600, iss 7889
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COVID-19 Host Genetics Initiative 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature, 2021, 600 (7889), pp.472-477. ⟨10.1038/s41586-021-03767-x⟩
Nature, Vol. 600, no. ²7889, p. 472-477 (2021)
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Nature, vol. 600, no. 7889, pp. 472-477
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Niemi, M E K, Karjalainen, J, Liao, R G, Neale, B M, Daly, M, Ganna, A, Pathak, G A, Andrews, S J, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E C, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M A, Wendt, F R, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M J, Smith, G D, Willer, C J, Buxbaum, J D, Karjalainen, J, Mehtonen, J, Folkersen, L, Moltke, I, Hinney, A, Wang, C, Ellinghaus, D, Brunak, S, Castro, P, Guindo-Martinez, M, Lee, J Y, Loos, R J F, Zhao, J H, Sun, Y V, Wang, B, Parker, R, Garcia, S M, Smith, O, Davis, C, COVID-19 Host Genetics Initiative, 23andMe COVID-19 Team, Norwegian SARS-CoV-2 Study Grp, Humanitas COVID-19 Task Force, Humanitas Gavazzeni COVID-19 Task, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Genes & Hlth Res Team & UCLA Hlth ATLAS Data Mart Working 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature (Lond.) 600 (2021): 472–+. doi:10.1038/s41586-021-03767-x
info:cnr-pdr/source/autori:Mari E. K. Niemi; Juha Karjalainen; Rachel G. Liao; Benjamin M. Neale; Mark Daly; Andrea Ganna; COVID-19 Host Genetics Initiative and the GEN-COVID Multicenter Study (including Stella, Alessandra and Biscarini, Filippo)/titolo:Mapping the human genetic architecture of COVID-19/doi:10.1038%2Fs41586-021-03767-x/rivista:Nature (Lond.)/anno:2021/pagina_da:472/pagina_a:+/intervallo_pagine:472–+/volume:600
Ganna, A & Davey Smith, G 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Nature 600, 472-477 (2021)
Baillie, J K, Wilson, J F, Bulteel, N, Hayward, C, Klaric, L, Porteous, D J, Russell, C D, Tenesa, A, Norman, L & Scott-Brown, J & Swann, O 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x

Niemi, Mari E. K. et al. 39 páginas, figuras y tablas. Contiene material suplementario.
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974d087615705cffb4d0d7bdc6394ffc
https://eprints.soton.ac.uk/456122/

A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct fromKabuki syndrome

Autor: Karen Stals, Sara Cuvertino, Víctor Faundes, Frances Flinter, Lihadh Al-Gazali, Santina Venuto, Vagheesh M. Narasimhan, Laura Southgate, Colin A. Johnson, Eamonn Sheridan, Nisha Nair, Anne Barton, Alice Colyer, Susan J. Kimber, Brian R. Jackson, Adam Stevens, Daniel Weisberg, Natalie Canham, Giuseppe Merla, Gabriella Maria Squeo, Richard C. Trembath, Sally Ann Lynch, Fatima Nadat, Terence Garner, Robert Sellers, Sian Ellard, Muriel Holder-Espinasse, David A. van Heel, Michelle Peckham, Francesca Montanari, Siddharth Banka, Verity L. Hartill, Marco Seri, Jozef Hertecant

Publikováno v: Cuvertino, S, Garner, T, Nair, N, Faundes Gomez, V, Sellers, R, Barton, A, Kimber, S, Banka, S & et al. 2020, ' A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome ', Genetics in Medicine . https://doi.org/10.1038/s41436-019-0743-3
Genetics in Medicine

Purpose: To investigate if specific exon 38 or 39 KMT2D missense variants (MVs) cause a condition distinct from Kabuki syndrome type 1 (KS1). Methods: Multiple individuals, with MVs in exons 38 or 39 of KMT2D that encode a highly conserved region of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb665ed7cd14c5769904b3a899659275
https://doi.org/10.1038/s41436-019-0743-3

A NGS-Targeted Autism/ID Panel Reveals Compound Heterozygous GNB5 Variants in a Novel Patient

Autor: Giuseppe Merla, William G. Wilson, Gabriella Maria Squeo, Katherine Keating, Natascia Malerba, Shelley Towner

Publikováno v: Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics

Homozygous and compound heterozygous pathogenic variants in GNB5 have been recently associated with a spectrum of clinical presentations varying from a severe multisystem form of the disorder including intellectual disability, early infantile develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eeec925cc802e5ae9a192fada4729d
https://www.frontiersin.org/article/10.3389/fgene.2018.00626/full

TRIM50 regulates Beclin 1 proautophagic activity

Autor: Lucia Micale, Gian Maria Fimia, Gabriella Maria Squeo, Carmela Fusco, Barbara Mandriani, Eva Sjøttem, Martina Di Rienzo, Dario Cocciadiferro, Natascia Malerba, Bartolomeo Augello, Giuseppe Merla, Ashish Jain, Maria Teresa Pellico, Terje Johansen

Autophagy is a catabolic process needed for maintaining cell viability and homeostasis in response to numerous stress conditions. Emerging evidence indicates that the ubiquitin system has a major role in this process. TRIMs, an E3 ligase protein fami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8543169120d73e5a9cde29475041d
http://hdl.handle.net/11573/1410993

Generation of the induced human pluripotent stem cell lines CSSi009-A from a patient with a GNB5 pathogenic variant, and CSSi010-A from a CRISPR/Cas9 engineered GNB5 knock-out human cell line

Autor: Raffaella Milanesi, Bartolomeo Augello, Lynette G. Sadleir, Giuseppe Merla, Patrizia Benzoni, Natascia Malerba, Gabriella Maria Squeo, Andrea Barbuti, Federica Giannetti, Gemma Poke, Anna Irma Croce

Publikováno v: Stem Cell Research, Vol 40, Iss, Pp-(2019)

GNB5 loss-of-function pathogenic variants cause IDDCA, a rare autosomal recessive human genetic disease characterized by infantile onset of intellectual disability, sinus bradycardia, hypotonia, visual abnormalities, and epilepsy. We generated human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95b19c76b4dc48eadfdf237c9c8d426
https://doi.org/10.1016/j.scr.2019.101547