Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Spyros Regoutas"'
Autor:
Christina Thanopoulou, Ioannis Papassotiriou, Spyros Regoutas, Kleopatra H. Schulpis, Aglaia Giannoulia-Karantana, George A. Karikas, Vassiliki Papaevangelou, Anastasia Bartzeliotou, Athena Fytou-Pallikari
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 69:31-35
Valproic acid (VPA) treatment and paraoxonase1/arylesterase (PON1/Aryl) activities are related to the production of free radicals. Our aim was to study the PON1/Aryl activities in children on VPA therapy.Thirty-two children with seizures and 30 healt
Autor:
Stylianos Tsakiris, Spyros Regoutas, Kleopatra H. Schulpis, George A. Karikas, Joanna Tjamouranis
Publikováno v:
Epilepsia. 42:1359-1362
Summary: Purpose: Valproic acid (VPA) is an effective antiepileptic drug (AED), which is associated with dose-related adverse reactions such as skin rash, hair loss (alopecia), etc. Profound as well as partial biotinidase deficiency causes dermatolog
Autor:
Stylianos Tsakiris, Spyros Regoutas, Alexandra Margeli, Christina Lazaropoulou, Kleopatra H. Schulpis, George A. Karikas, Ioannis Papassotiriou
Publikováno v:
Toxicology. 217(2-3)
Valproic acid (VPA) and 8-hydroxy-2-deoxyguanosine (8-OHdG) are implicated with the free radicals production. We aimed to evaluate total oxidant status (TOS) and 8-OHdG in children on VPA monotherapy. Fifty patients with seizures, mean age 8.5+/-3.6