Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Spyros Oikonomopoulos"'
Autor:
Samer Girgis, Zaikun Xu, Spyros Oikonomopoulos, Alla D. Fedorova, Egor P. Tchesnokov, Calvin J. Gordon, T. Martin Schmeing, Matthias Götte, Nahum Sonenberg, Pavel V. Baranov, Jiannis Ragoussis, Tom C. Hobman, Jerry Pelletier
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Genomes from defective interfering (DI) particles following serial passaging of SARS-CoV-2 reveal a fusion protein that attenuates viral replication. Synthetic, recombinant DI genomes are designed to interfere with SARS-CoV-2 replication.
Externí odkaz:
https://doaj.org/article/5e493b54c37c47c3a8ea41d5c87f53e3
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Full-length transcript sequencing remains a main goal of RNA sequencing. However, even the application of long-read sequencing technologies such as Oxford Nanopore Technologies still fail to yield full-length transcript sequencing for a significant p
Externí odkaz:
https://doaj.org/article/8bd94e05e813497c88d5d032331761e3
Autor:
Anthony Bayega, Spyros Oikonomopoulos, Maria-Eleni Gregoriou, Konstantina T. Tsoumani, Antonis Giakountis, Yu Chang Wang, Kostas D. Mathiopoulos, Jiannis Ragoussis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The olive fruit fly, Bactrocera oleae, is the most important pest for the olive fruit but lacks adequate transcriptomic characterization that could aid in molecular control approaches. We apply nanopore long-read RNA-seq with internal RNA st
Externí odkaz:
https://doaj.org/article/6c207f6e60fd436084be6381858ad281
Autor:
Xue Wu, Cristina M. Niculite, Mihai Bogdan Preda, Annalisa Rossi, Toma Tebaldi, Elena Butoi, Mattie K. White, Oana M. Tudoran, Daniela N. Petrusca, Amber S. Jannasch, William P. Bone, Xingyue Zong, Fang Fang, Alexandrina Burlacu, Michelle T. Paulsen, Brad A. Hancock, George E. Sandusky, Sumegha Mitra, Melissa L. Fishel, Aaron Buechlein, Cristina Ivan, Spyros Oikonomopoulos, Myriam Gorospe, Amber Mosley, Milan Radovich, Utpal P. Davé, Jiannis Ragoussis, Kenneth P. Nephew, Bernard Mari, Alan McIntyre, Heiko Konig, Mats Ljungman, Diana L. Cousminer, Paolo Macchi, Mircea Ivan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Noncoding transcripts contribute to the adaptation of cellular processes to oxygen levels. Here the authors characterize a hypoxia responsive lncRNA lincNORS and show that it has a role in cellular sterol homeostasis.
Externí odkaz:
https://doaj.org/article/52284dde8b4044179316ad15dd802151
Autor:
Spyros Oikonomopoulos, Anthony Bayega, Somayyeh Fahiminiya, Haig Djambazian, Pierre Berube, Jiannis Ragoussis
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
RNA sequencing using next-generation sequencing technologies (NGS) is currently the standard approach for gene expression profiling, particularly for large-scale high-throughput studies. NGS technologies comprise high throughput, cost efficient short
Externí odkaz:
https://doaj.org/article/245a26822df34a778c38c4a3b1bac63a
Autor:
Xue Wu, Cristina M. Niculite, Mihai Bogdan Preda, Annalisa Rossi, Toma Tebaldi, Elena Butoi, Mattie K. White, Oana M. Tudoran, Daniela N. Petrusca, Amber S. Jannasch, William P. Bone, Xingyue Zong, Fang Fang, Alexandrina Burlacu, Michelle T. Paulsen, Brad A. Hancock, George E. Sandusky, Sumegha Mitra, Melissa L. Fishel, Aaron Buechlein, Cristina Ivan, Spyros Oikonomopoulos, Myriam Gorospe, Amber Mosley, Milan Radovich, Utpal P. Davé, Jiannis Ragoussis, Kenneth P. Nephew, Bernard Mari, Alan McIntyre, Heiko Konig, Mats Ljungman, Diana L. Cousminer, Paolo Macchi, Mircea Ivan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a1daa57c1a454e498c953cd0ba7dceb4
Autor:
David G. Saliba, Andreas Heger, Hayley L. Eames, Spyros Oikonomopoulos, Ana Teixeira, Katrina Blazek, Ariadne Androulidaki, Daniel Wong, Fui G. Goh, Miriam Weiss, Adam Byrne, Manolis Pasparakis, Jiannis Ragoussis, Irina A. Udalova
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1308-1317 (2014)
Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analys
Externí odkaz:
https://doaj.org/article/62176b6cba9e405491e69a22de5b11c8
Autor:
Nicholas Redshaw, Carme Camps, Vikas Sharma, Mehdi Motallebipour, Marcela Guzman-Ayala, Spyros Oikonomopoulos, Efstathia Thymiakou, Jiannis Ragoussis, Vasso Episkopou
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55186 (2013)
The Transforming Growth Factor-β (TGF-β) signaling pathway is one of the major pathways essential for normal embryonic development and tissue homeostasis, with anti-tumor but also pro-metastatic properties in cancer. This pathway directly regulates
Externí odkaz:
https://doaj.org/article/0a2eba45ff01472ab54a4c533d4d69f3
Autor:
Somayyeh Fahiminiya, Spyros Oikonomopoulos, Georges‐Etienne Rivard, Mira Gandhi, Patrick Scott, Alexandre Montpetit, Shu‐Huang Chen, KyungHee Park, Catherine Vezina, Jiannis Ragoussis, Claudia M. B. Carvalho, Grant A. Mitchell, Jean‐Francois Soucy, Julie Gauthier
Publikováno v:
Haemophilia. 29:921-924
Autor:
Jiannis Ragoussis, Maria-Eleni Gregoriou, Spyros Oikonomopoulos, Kostas D. Mathiopoulos, Anthony Bayega, Konstantina T. Tsoumani, Yu Chang Wang, Antonis Giakountis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
The olive fruit fly, Bactrocera oleae, is the most important pest for the olive fruit but lacks adequate transcriptomic characterization that could aid in molecular control approaches. We apply nanopore long-read RNA-seq with internal RNA standards a