Výsledky vyhledávání - "Spyros Efthimiopoulos"

Discovery of novel phenoxazinone derivatives as DKK1/LRP6 interaction inhibitors: Synthesis, biological evaluation and structure–activity relationships

Autor: Athanasios D. Balomenos, Sotirios Katsamakas, Savvas Thysiadis, Nicolaos Avramidis, Rosaria Remelli, Spyros Mpousis, Vasiliki Sarli, Spyros Efthimiopoulos

Publikováno v: Bioorganic & Medicinal Chemistry. 24:1014-1022

Amino derivatives of NCI8642 were synthesized and evaluated as inhibitors of DKK1/LRP6 interactions. The new inhibitors were able to activate the Wnt signaling pathway as indicated by the increased levels of β-catenin, and decrease the DKK1-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e6b3d3e5cde977d61d03b7e5487e93
https://doi.org/10.1016/j.bmc.2016.01.025

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Inhibitory Activity on Amyloid-β Aggregation and Antioxidant Properties of Crocus sativus Stigmas Extract and Its Crocin Constituents

Autor: Magdalini A. Papandreou, Spyros Efthimiopoulos, Paul Cordopatis, Fotini N. Lamari, Marigoula Margarity, Charalambos D. Kanakis, Moschos G. Polissiou

Publikováno v: Journal of Agricultural and Food Chemistry. 54:8762-8768

Crocus sativus stigmas are one of the widely known spices (saffron) and consist of unusually polar carotenoids. Alzheimer's disease is characterized pathologically by deposition of amyloid beta-peptide (Abeta) fibrils. Oxidation is thought to promote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29f9f16376b78e3f91ca726dbaa3d73
https://doi.org/10.1021/jf061932a

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P1‐320: STUDY OF THE EFFECT OF GLUCOSE AND OXYGEN DEPRIVATION ON THE PHOSPHORYLATION OF TAU

Autor: Elpiniki Pappa, Panagiota Mavroeidi, Myrto Panopoulou, Spyros Efthimiopoulos, Olga Mavrofrydi

Publikováno v: Alzheimer's & Dementia. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eccd85c8d32c22e7308e5f75b373cc64
https://doi.org/10.1016/j.jalz.2014.05.561

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HLA-DRB1* Allele Frequencies in Pediatric, Adolescent and Adult-Onset Multiple Sclerosis Patients, in a Hellenic Sample. Evidence for New and Established Associations

Autor: Sotirios Youroukos, Argyro Manouseli, Artemios Artemiadis, Constantina Fillipopoulou, Maria Anagnostouli, Spyros Efthimiopoulos, Serafeim Katsavos, Ilias Doxiadis

Publikováno v: Journal of Multiple Sclerosis.

Studies in many populations consistently have showed that the human leukocyte antigens (HLA) and especially the DRB1*15 allele has by far the strongest genetic association with multiple sclerosis (MS). The aim of this study was to investigate the rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d19b614c2d7c104f692e091f5aeb5455
https://doi.org/10.4172/jmso.1000104

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