A novel Bim-BH3-derived Bcl-XL inhibitor

Autor: Ponassi, R, Biasotti, B, Tomati, V, Bruno, S, Poggi, A, Malacarne, D, Cimoli, G, Salis, A, Pozzi, S, Miglino, M, Damonte, G, Cozzini, P, Spyraki, F, Campanini, B, Bagnasco, L, Castagnino, N, Tortolina, L, Mumot, A, Frassoni, F, Daga, A, Cilli, M, Piccardi, F, Monfardini, I, Perugini, M, Zoppoli, G, Darrigo, C, Pesenti, Raffaele, Parodi, S.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3655::1fe376a57dca46bba19d45d40f79cc60
http://hdl.handle.net/10278/20504

A novel Bim-BH3-derived Bcl-XL inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity

Autor: Ponassi R, Biasotti B, Tomati V, Bruno S, Poggi A, Malacarne D, Cimoli G, Salis A, Pozzi S, Miglino M, Damonte G, Cozzini P, Spyrakis F, Spyraki F, Campanini B, Bagnasco L, Castagnino N, Tortolina L, Mumot A, Frassoni F, Antonio Daga, Cilli M, Piccardi F, Monfardini I, Perugini M, Zoppoli G, D'Arrigo C, Pesenti R, Parodi S

Publikováno v: Scopus-Elsevier
Europe PubMed Central
Cell cycle (Georget. Tex.) 7 (2008): 3211–3224. doi:10.4161/cc.7.20.6830
info:cnr-pdr/source/autori:Ponassi R.; Biasotti B.; Tomati V.; Bruno S.; Poggi A.; Malacarne D.; Cimoli G.; Salis A.; Pozzi S.; Miglino M.; Damonte G.; Cozzini P.; Spyraki F.; Campanini B.; Bagnasco L.; Castagnino N.; Tortolina L.; Mumot A.; Frassoni F.; Daga A.; Cilli M.; Piccardi F.; Monfardini I.; Perugini M.; Zoppoli G.; D'Arrigo C.; Pesenti R.; Parodi S./titolo:A novel Bim-BH3-derived Bcl-X(L) inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity/doi:10.4161%2Fcc.7.20.6830/rivista:Cell cycle (Georget. Tex.)/anno:2008/pagina_da:3211/pagina_a:3224/intervallo_pagine:3211–3224/volume:7

BH3-only members of the Bcl-2 family exert a fundamental role in apoptosis induction. This work focuses on the development of a novel peptidic molecule based on the BH3 domain of Bim. The antiapoptotic molecule Bcl-X(L), involved in cancer developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e111c753430f24d31ec495cf79e0bb9
http://www.scopus.com/inward/record.url?eid=2-s2.0-54049131208&partnerID=MN8TOARS