Machine Learning Analysis Using RNA Sequencing to Distinguish Neuromyelitis Optica from Multiple Sclerosis and Identify Therapeutic Candidates.

Autor: Wylezinski LS; Decode Health, Inc., Nashville, Tennessee; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee., Sesler CL; Decode Health, Inc., Nashville, Tennessee., Shaginurova GI; Decode Health, Inc., Nashville, Tennessee., Grigorenko EV; Decode Health, Inc., Nashville, Tennessee., Wohlgemuth JG; Quest Diagnostics, Secaucus, New Jersey; Trusted Health Advisors, San Juan Capistrano, California., Cockerill FR 3rd; Decode Health, Inc., Nashville, Tennessee; Trusted Health Advisors, San Juan Capistrano, California; Department of Medicine, Rush University Medical Center, Chicago, Illinois., Racke MK; Quest Diagnostics, Secaucus, New Jersey., Spurlock CF 3rd; Decode Health, Inc., Nashville, Tennessee; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; Wagner School of Public Service, New York University, New York, New York. Electronic address: chase@decodehealth.ai.

Publikováno v: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2024 Jun; Vol. 26 (6), pp. 520-529. Date of Electronic Publication: 2024 Mar 22.

Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis.

Autor: Heinrich MJ; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Purcell CA; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Pruijssers AJ; Departments of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Zhao Y; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Spurlock CF 3rd; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Sriram S; Departments of Neurology, Vanderbilt University Medical Center, Nashville, TN, 37212, USA., Ogden KM; Departments of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Dermody TS; Departments of Pediatrics and of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Scholz MB; Vanderbilt Technologies for Advanced Genomics, Vanderbilt University Medical Center, Nashville, TN, 37212, USA., Crooke PS 3rd; Department of Mathematics, Vanderbilt University, Nashville, TN, 37212, USA., Karijolich J; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Aune TM; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA. Electronic address: tom.aune@vanderbilt.edu.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2019 Jun; Vol. 100, pp. 40-51. Date of Electronic Publication: 2019 Feb 28.

Longitudinal changes in the expression of IL-33 and IL-33 regulated genes in relapsing remitting MS.

Autor: Sriram S; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States of America., Shaginurova G; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.; IQuity, Inc., Nashville, TN, United States of America., Tossberg JT; IQuity, Inc., Nashville, TN, United States of America., Natarajan C; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States of America., Spurlock CF 3rd; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America., Aune TM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.; Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America.

Publikováno v: PloS one [PLoS One] 2018 Dec 18; Vol. 13 (12), pp. e0208755. Date of Electronic Publication: 2018 Dec 18 (Print Publication: 2018).

Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells.

Autor: Spurlock CF 3rd; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232., Shaginurova G; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232., Tossberg JT; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232., Hester JD; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232., Chapman N; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232., Guo Y; Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232., Crooke PS 3rd; Department of Mathematics, Vanderbilt University, Nashville, TN 37240; and., Aune TM; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; tom.aune@vanderbilt.edu.; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Jul 15; Vol. 199 (2), pp. 547-558. Date of Electronic Publication: 2017 Jun 09.

Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.

Autor: Spurlock CF 3rd; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and., Crooke PS 3rd; Department of Mathematics, Vanderbilt University, Nashville, TN 37232., Aune TM; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and tom.aune@vanderbilt.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Dec 15; Vol. 197 (12), pp. 4509-4517.