Machine Learning Analysis Using RNA Sequencing to Distinguish Neuromyelitis Optica from Multiple Sclerosis and Identify Therapeutic Candidates.

Autor: Wylezinski LS; Decode Health, Inc., Nashville, Tennessee; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee., Sesler CL; Decode Health, Inc., Nashville, Tennessee., Shaginurova GI; Decode Health, Inc., Nashville, Tennessee., Grigorenko EV; Decode Health, Inc., Nashville, Tennessee., Wohlgemuth JG; Quest Diagnostics, Secaucus, New Jersey; Trusted Health Advisors, San Juan Capistrano, California., Cockerill FR 3rd; Decode Health, Inc., Nashville, Tennessee; Trusted Health Advisors, San Juan Capistrano, California; Department of Medicine, Rush University Medical Center, Chicago, Illinois., Racke MK; Quest Diagnostics, Secaucus, New Jersey., Spurlock CF 3rd; Decode Health, Inc., Nashville, Tennessee; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; Wagner School of Public Service, New York University, New York, New York. Electronic address: chase@decodehealth.ai.

Publikováno v: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2024 Jun; Vol. 26 (6), pp. 520-529. Date of Electronic Publication: 2024 Mar 22.

R-loops' m6A modification and its roles in cancers.

Autor: Qiu, Yue¹ (AUTHOR), Man, Changfeng¹ (AUTHOR), Zhu, Luyu² (AUTHOR), Zhang, Shiqi² (AUTHOR), Wang, Xiaoyan² (AUTHOR) 726343819@qq.com, Gong, Dandan¹ (AUTHOR) godan121986@163.com, Fan, Yu¹ (AUTHOR) yuf12345@ujs.edu.cn

Publikováno v: Molecular Cancer. 10/18/2024, Vol. 23 Issue 1, p1-14. 14p.

Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis.

Autor: Heinrich MJ; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Purcell CA; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Pruijssers AJ; Departments of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Zhao Y; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Spurlock CF 3rd; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Sriram S; Departments of Neurology, Vanderbilt University Medical Center, Nashville, TN, 37212, USA., Ogden KM; Departments of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Dermody TS; Departments of Pediatrics and of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Scholz MB; Vanderbilt Technologies for Advanced Genomics, Vanderbilt University Medical Center, Nashville, TN, 37212, USA., Crooke PS 3rd; Department of Mathematics, Vanderbilt University, Nashville, TN, 37212, USA., Karijolich J; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Aune TM; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN 37212, USA; Departments of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA. Electronic address: tom.aune@vanderbilt.edu.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2019 Jun; Vol. 100, pp. 40-51. Date of Electronic Publication: 2019 Feb 28.

Longitudinal changes in the expression of IL-33 and IL-33 regulated genes in relapsing remitting MS.

Autor: Sriram S; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States of America., Shaginurova G; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.; IQuity, Inc., Nashville, TN, United States of America., Tossberg JT; IQuity, Inc., Nashville, TN, United States of America., Natarajan C; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States of America., Spurlock CF 3rd; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America., Aune TM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.; Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America.

Publikováno v: PloS one [PLoS One] 2018 Dec 18; Vol. 13 (12), pp. e0208755. Date of Electronic Publication: 2018 Dec 18 (Print Publication: 2018).

The landscape of immune checkpoint-related long non-coding RNAs core regulatory circuitry reveals implications for immunoregulation and immunotherapy responses.

Autor: Qu, Changfan¹ (AUTHOR), Cui, Hao² (AUTHOR), Xiao, Song¹ (AUTHOR), Dong, Longlong¹ (AUTHOR), Lu, Qianyi¹ (AUTHOR), Zhang, Lei² (AUTHOR), Wang, Peng¹ (AUTHOR), Xin, Mengyu¹ (AUTHOR), Zhi, Hui¹ (AUTHOR), Liu, Chenyu¹ (AUTHOR), Ning, Shangwei¹ (AUTHOR) ningsw@ems.hrbmu.edu.cn, Gao, Yue¹ (AUTHOR) gaoyue_hrm@163.com

Publikováno v: Communications Biology. 3/14/2024, Vol. 7 Issue 1, p1-14. 14p.