Fatty acid binding protein 5 inhibition attenuates pronociceptive cytokine/chemokine expression and suppresses osteoarthritis pain: A comparative human and rat study.

Autor: Gordon C; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Trainor J; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Shah RJ; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Studholme K; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Gelman A; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Doswell F; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Sadar F; Department of Orthopaedics and Rehabilitation, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Giovannetti A; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Gershenson J; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Khan A; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Nicholson J; Department of Orthopaedics and Rehabilitation, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Huang Z; Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China., Spurgat M; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Tang SJ; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA; Stony Brook University Pain and Analgesia Research Center (SPARC), Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA., Wang H; Department of Chemistry, Stony Brook University, Stony Brook, NY, USA., Ojima I; Department of Chemistry, Stony Brook University, Stony Brook, NY, USA; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, USA., Carlson D; Genomics Core Facility and Institute for Advanced Computational Sciences, Stony Brook University, Stony Brook, NY, USA., Komatsu DE; Department of Orthopaedics and Rehabilitation, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA. Electronic address: david.komatsu@stonybrookmedicine.edu., Kaczocha M; Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA; Stony Brook University Pain and Analgesia Research Center (SPARC), Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, USA. Electronic address: Martin.Kaczocha@Stonybrook.edu.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2024 Mar; Vol. 32 (3), pp. 266-280. Date of Electronic Publication: 2023 Nov 28.

Induced pluripotent stem cells for cardiovascular therapeutics: Progress and perspectives.

Autor: Kizub, I. V.¹ IgorKizub@hdbiosciences.com

Publikováno v: Regulatory Mechanisms in Biosystems. 2023, Vol. 14 Issue 3, p451-468. 18p.

ART26.12, a novel fatty acid-binding protein 5 inhibitor, shows efficacy in multiple preclinical neuropathy models.

Autor: Warren WG; Artelo Biosciences Ltd., Alderley Park, Alderley Edge, Cheshire, UK., Osborn M; Artelo Biosciences Ltd., Alderley Park, Alderley Edge, Cheshire, UK., David-Pereira A; Transpharmation Ltd., The London Bioscience Innovation Centre, London, UK., Tsantoulas C; Transpharmation Ltd., The London Bioscience Innovation Centre, London, UK., Xue W; Pharmaron Inc., Beijing, People's Republic of China., Yates A; Artelo Biosciences Ltd., Alderley Park, Alderley Edge, Cheshire, UK., OSullivan SE; Artelo Biosciences Ltd., Alderley Park, Alderley Edge, Cheshire, UK.

Publikováno v: European journal of pain (London, England) [Eur J Pain] 2024 Aug 26. Date of Electronic Publication: 2024 Aug 26.

Tackling the glial scar in spinal cord regeneration: new discoveries and future directions.

Autor: Shafqat, Areez, Albalkhi, Ibrahem, Magableh, Hamzah M., Saleh, Tariq, Alkattan, Khaled, Yaqinuddin, Ahmed

Publikováno v: Frontiers in Cellular Neuroscience; 2023, p1-24, 24p

Caspase-dependent apoptosis induces reactivation and gliogenesis of astrocytes in adult mice.

Autor: Seung-Chan Kim, Jae-Yong Park, Eun Mi Hwang

Publikováno v: Frontiers in Cellular Neuroscience; 11/30/2022, Vol. 16, p01-11, 11p, 1 Diagram, 3 Graphs