Added Value of 50-Gene Panel Sequencing to Distinguish Multiple Primary Lung Cancers from Pulmonary Metastases: A Systematic Investigation

Autor: Roepman, Paul, Ten Heuvel, Alexandra, Scheidel, Karen C, Sprong, Tobias, Heideman, Danielle A M, Seldenrijk, Kees A, Herder, Gerarda J M, Kummer, J Alain

Publikováno v: The Journal of molecular diagnostics, 20(4), 436-445. Association of Molecular Pathology
Roepman, P, Ten Heuvel, A, Scheidel, K C, Sprong, T, Heideman, D A M, Seldenrijk, K A, Herder, G J M & Kummer, J A 2018, ' Added Value of 50-Gene Panel Sequencing to Distinguish Multiple Primary Lung Cancers from Pulmonary Metastases : A Systematic Investigation ', The Journal of molecular diagnostics, vol. 20, no. 4, pp. 436-445 . https://doi.org/10.1016/j.jmoldx.2018.02.007

Differentiation between multiple primary lung cancers and pulmonary metastases (PM) has important implications in staging, prognosis, and treatment strategies. Clinical and immunohistopathologic criteria have been standardized; however, a substantial

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https://research.vumc.nl/en/publications/08c0b0cf-e6d6-40ba-9c72-deb4b24be175