Výsledky vyhledávání - "Sproll, Marlies"

Characterization of a high-affinity monoclonal antibody specific for CD44v6 as candidate for immunotherapy of squamous cell carcinomas

Autor: Susanne Susani, Elinborg Ostermann, Paul Beaumier, Horst Ahorn, Erik Patzelt, Günther R. Adolf, Karl Heinz Heider, Sproll Marlies

Publikováno v: Cancer Immunology, Immunotherapy. 43:245-253

Variant isoforms of CD44, a family of cell-surface glycoproteins generated by alternative splicing and post-translational modifications, are expressed in a variety of human tumors and play important roles in tumor progression and metastasis formation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a164627c42cf61c7f0ac2517e575207
https://doi.org/10.1007/s002620050329

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Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head-and-neck cancer xenografts

Autor: Erik Patzelt, Guus A.M.S. van Dongen, Karl Heinz Heider, Iris Verel, Sproll Marlies, Gordon B. Snow, Günther R. Adolf, Miranda Siegmund, Elinborg Ostermann

Publikováno v: Verel, I, Heider, K H, Siegmund, M, Ostermann, E, Patzelt, E, Sproll, M, Snow, G B, Adolf, G R & Van Dongen, G A M S 2002, ' Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head-and-neck cancer xenografts ', International Journal of Cancer, vol. 99, no. 3, pp. 396-402 . https://doi.org/10.1002/ijc.10369
International Journal of Cancer, 99(3), 396-402. Wiley-Liss Inc.

The CD44 protein family consists of isoforms with tissue-specific expression, which are encoded by standard exons and up to 9 alternatively spliced variant exons (v2-v10) of the same gene. The murine MAbs U36 and BIWA-1, directed against overlapping

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc696db44541ffaf3e83519925c1f02f
https://research.vumc.nl/en/publications/52feb604-9bf0-4fda-9476-40a980aebb99

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Safety and biodistribution of 99mtechnetium-labeled anti-CD44v6 monoclonal antibody BIWA 1 in head and neck cancer patients

Autor: Stroomer, Joep W.G., Roos, Jan C., Sproll, Marlies, Quak, Jasper J., Heider, Karl Heinz, Wilhelm, Bram J., Castelijns, Jonas A., Meyer, Reiner, Kwakkelstein, Marthin O., Snow, Gordon B., Adolf, Günther R., Van Dongen, Guus A.M.S.

Publikováno v: Clinical Cancer Research, 6(8), 3046-3055. American Association for Cancer Research Inc.

The CD44 protein family consists of isoforms, encoded by standard exons and up to nine alternatively spliced variant exons (v2-v10), which are expressed in a tissue-specific way. Expression of v6-containing variants (CD44v6) has been related to aggre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a230e0437152cc51309eb55ac10c4513
https://research.vumc.nl/en/publications/6cb3d2c8-cf10-4950-8c43-5ef37d45ca31

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