Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology.

Autor: Rodriguez Pena MDC; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, 35233, USA.; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA., Springer SU; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, MD, 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21231, USA., Taheri D; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA.; Department of Pathology, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Li L; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, MD, 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21231, USA., Tregnago AC; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA., Eich ML; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, 35233, USA.; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA., Eltoum IA; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, 35233, USA., VandenBussche CJ; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA., Papadopoulos N; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, MD, 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21231, USA., Kinzler KW; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, MD, 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21231, USA., Vogelstein B; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, MD, 21231, USA.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21231, USA., Netto GJ; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, 35233, USA. gnetto@uabmc.edu.; Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, 21231, USA. gnetto@uabmc.edu.

Publikováno v: Virchows Archiv : an international journal of pathology [Virchows Arch] 2020 Mar; Vol. 476 (3), pp. 423-429. Date of Electronic Publication: 2019 Sep 03.

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations.

Autor: Palsgrove DN; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Taheri D; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA; Department of Pathology, Isfahan University of Medical Sciences, Isfahan Kidney Diseases Research Center, Isfahan 81746 73461, Iran., Springer SU; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Cowan M; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Guner G; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Mendoza Rodriguez MA; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Rodriguez Pena MDC; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Wang Y; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Kinde I; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Ricardo BFP; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA., Cunha I; Department of Pathology, Rede D'OR São Luiz, São Paulo 03313-000, Brazil., Fujita K; Department of Urology, Osaka University, Osaka 565-0871, Japan., Ertoy D; Department of Pathology, Koç University, İstanbul 34450, Turkey., Kinzler KW; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Bivalacqua TJ; Department of Urology, Johns Hopkins University, Baltimore, MD 21287, USA., Papadopoulos N; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Vogelstein B; Department of Oncology, Johns Hopkins University, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutics and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA., Netto GJ; Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA. Electronic address: gnetto@uabmc.edu.

Publikováno v: Human pathology [Hum Pathol] 2019 Mar; Vol. 85, pp. 1-9. Date of Electronic Publication: 2018 Nov 14.

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Autor: Springer SU; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Chen CH; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan., Rodriguez Pena MDC; Department of Pathology, Johns Hopkins University, Baltimore, United States.; Department of Pathology, University of Alabama at Birmingham, Birmingham, United States., Li L; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States., Douville C; Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, United States., Wang Y; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Cohen JD; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Taheri D; Department of Pathology, Johns Hopkins University, Baltimore, United States.; Department of Pathology, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Silliman N; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Schaefer J; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Ptak J; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Dobbyn L; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Papoli M; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Kinde I; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Afsari B; Department of Oncology, Johns Hopkins University, Baltimore, United States.; Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, United States., Tregnago AC; Department of Pathology, Johns Hopkins University, Baltimore, United States., Bezerra SM; Department of Pathology, AC Camargo Cancer Center, Sao Paulo, Brazil., VandenBussche C; Department of Pathology, Johns Hopkins University, Baltimore, United States., Fujita K; Department of Pathology, Osaka University, Osaka, Japan., Ertoy D; Department of Pathology, Hacettepe University, Ankara, Turkey., Cunha IW; Department of Pathology, AC Camargo Cancer Center, Sao Paulo, Brazil., Yu L; Department of Pathology, University of Alabama at Birmingham, Birmingham, United States., Bivalacqua TJ; Department of Urology, Johns Hopkins University, Baltimore, United States., Grollman AP; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, United States.; Department of Medicine, Stony Brook University, Stony Brook, United States., Diaz LA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, United States., Karchin R; Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, United States.; Department of Oncology, Johns Hopkins University, Baltimore, United States., Danilova L; Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, United States.; Department of Pathology, Hacettepe University, Ankara, Turkey., Huang CY; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan., Shun CT; Department of Forensic Medicine and Pathology, National Taiwan University Hospital, Taipei, Taiwan., Turesky RJ; Masonic Cancer Center, University of Minnesota, Minneapolis, United States.; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, United States., Yun BH; Masonic Cancer Center, University of Minnesota, Minneapolis, United States.; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, United States., Rosenquist TA; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, United States., Pu YS; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan., Hruban RH; Department of Pathology, Johns Hopkins University, Baltimore, United States., Tomasetti C; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.; Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore, United States., Papadopoulos N; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Kinzler KW; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Vogelstein B; Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, United States.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Dickman KG; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, United States.; Department of Medicine, Stony Brook University, Stony Brook, United States., Netto GJ; Department of Pathology, Johns Hopkins University, Baltimore, United States.; Department of Pathology, University of Alabama at Birmingham, Birmingham, United States.

Publikováno v: ELife [Elife] 2018 Mar 20; Vol. 7. Date of Electronic Publication: 2018 Mar 20.