Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Spriha, Gogia"'
Autor:
Zeyu, Li, Spriha, Gogia, Kathleen S, Tatem, Caroline, Cooke, Jesse, Singer, Dave A, Chokshi, Remle, Newton-Dame
Publikováno v:
Medical Care. 61:102-108
Health care facilities use predictive models to identify patients at risk of high future health care utilization who may benefit from tailored interventions. Previous predictive models that have focused solely on inpatient readmission risk, relied on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308989313c1a247965b84275fbdb3c8d
https://doi.org/10.1097/mlr.0000000000001807
https://doi.org/10.1097/mlr.0000000000001807
Publikováno v:
ChemPhysChem. 16:2172-2181
Plasmodium falciparum (Pf) hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is a potential therapeutic target. Compared to structurally homologous human enzymes, it has expanded substrate specificity. In this study, 9-deazapurines are used as i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1921da776fce918dbf0d8276ea070d
https://doi.org/10.1002/cphc.201500084
https://doi.org/10.1002/cphc.201500084
Publikováno v:
The Journal of Physical Chemistry B. 113:15101-15118
6-Oxopurine and its analogues form an important class of biological molecules that include nucleobases and their precursors and are substrates of a wide range of enzymes. Solution structures of purines have been debated in the literature because of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709d968bf19d475caab29aca0596c216
https://doi.org/10.1021/jp9057753
https://doi.org/10.1021/jp9057753
Publikováno v:
The FASEB Journal. 29
Enzymes of the salvage pathway are essential to understanding the biochemistry of parasitic protozoa. These parasites lack de novo pathway for nucleotide synthesis and depend solely on purines salv...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8595d201f7d5b3951242dd50e641720e
https://doi.org/10.1096/fasebj.29.1_supplement.721.19
https://doi.org/10.1096/fasebj.29.1_supplement.721.19
Autor:
Spriha Gogia, Mrinalini Puranik
Publikováno v:
Journal of biomolecular structuredynamics. 32(1)
Analogues of purine bases are highly relevant in the biological context and have been implicated as drug molecules for therapy against a number of diseases. Additionally, these molecules have been implicated to have a role in the prebiotic RNA world.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bfa936fd410c65e051025ae848ebc5
https://pubmed.ncbi.nlm.nih.gov/23384120
https://pubmed.ncbi.nlm.nih.gov/23384120
Publikováno v:
Biochemistry. 50(19)
Enzymatic efficiency and structural discrimination of substrates from nonsubstrate analogues are attributed to the precise assembly of binding pockets. Many enzymes have the additional remarkable ability to recognize several substrates. These apparen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daf22a8f952d267036c50247e907921
https://pubmed.ncbi.nlm.nih.gov/21486037
https://pubmed.ncbi.nlm.nih.gov/21486037
Autor:
Sayan Mondal, Spriha Gogia, Namrata Jayanth, Mrinalini Puranik, P. M. Champion, L. D. Ziegler
Publikováno v:
AIP Conference Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e70ba81b7e67260eebb2e890b8e68c8
https://doi.org/10.1063/1.3482546
https://doi.org/10.1063/1.3482546
Publikováno v:
Biophysical Journal. (3):657a
Purines and pyrimidines that form the nucleobases in normal and modified DNA and RNA are known to exist in several tautomeric and ionization states. The relative populations of tautomers in solution and their precise structure are highly sensitive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa98c4714a82e67a78f725011d3e809