Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Spriggs Keith A"'
Publikováno v:
Molecular Cancer, Vol 9, Iss 1, p 226 (2010)
Abstract PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumours. The physiological functions of PRAME in normal and tumour cells are unknown, although a role in the re
Externí odkaz:
https://doaj.org/article/bb8f5a9ccab844869a941e69229b941c
Autor:
Surani, Arif A., Spriggs, Keith A., Ufer, Christoph, Polytarchou, Christos, Montiel-Duarte, Cristina
Publikováno v:
In iScience 22 December 2022 25(12)
Akademický článek
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Autor:
Gurnani, Pratik, Alazzo, Ali, Gumus, Nurcan, Stolnik, Snjezana, Rahman, Ruman, Spriggs, Keith, Alexander, Cameron
The temporary silencing of disease-associated genes utilising short interfering RNA (siRNA) is a potent and selective route for addressing a wide range of life limiting disorders. However, the few clinically approved siRNA therapies rely on lipid bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::bc570f69c904a0890ac90d95cfec879c
Autor:
Kong, Yi Wen, Cannell, Ian G., de Moor, Cornelia H., Hill, Kirsti, Garside, Paul G., Hamilton, Tiffany L., Meijer, Hedda A., Dobbyn, Helen C., Stoneley, Mark, Spriggs, Keith A., Willis, Anne E., Bushell, Martin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Jul 01. 105(26), 8866-8871.
Externí odkaz:
https://www.jstor.org/stable/25462884
Akademický článek
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Autor:
Taresco, Vincenzo, Abelha, Thais F., Cavanagh, Robert J., Vasey, Catherine E., Anane-Adjei, Akosua B., Pearce, Amanda K., Spriggs, Keith A., Clarke, Philip, Ritchie, Alison, Martin, Stewart, Rahman, Ruman, Grabowska, Anna M., Ashford, Marianne B., Alexander, Cameron
Amphiphilic block co-polymers composed of poly(ethylene glycol)-co-poly(lactide)-co-poly(2-((tert-butoxycarbonyl)amino)-3-propyl carbonate) (PEG-pLA-pTBPC) are synthesized in monomer ratios and arrangements to enable assembly into nanoparticles with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c72c0d5b7556b80c25596e8cae2419ef
https://nottingham-repository.worktribe.com/file/4770523/1/adtp.202000103
https://nottingham-repository.worktribe.com/file/4770523/1/adtp.202000103
Autor:
Alazzo, Ali, Gumus, Nurcan, Gurnani, Pratik, Stolnik, Snjezana, Rahman, Ruman, Spriggs, Keith, Alexander, Cameron
Publikováno v:
Journal of Materials Chemistry B; 1/14/2022, Vol. 10 Issue 2, p236-246, 11p
Autor:
Alazzo, Ali, Al-Natour, Mohammad, Spriggs, Keith, Stolnik, Snjezana, Ghaemmaghami, Amir, Kim, Dong-Hyun, Alexander, Cameron
Cationic polymers have emerged as a promising alternative to viral vectors in gene therapy. They are cheap to scale up, easy to functionalise and also presume to be safer than the viral vectors, however many of them are cytotoxic. The large number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::82ff3992c288ba4a81d123fee4a0c7be
Autor:
Alazzo, Ali, Lovato, Tatiana, Collins, Hilary M., Taresco, Vincenzo, Stolnik, Snjezana, Soliman, Mahmoud E., Spriggs, Keith, Alexander, Cameron
The successful clinical translation of non-viral gene delivery systems has yet to be achieved due to the biological and technical obstacles to preparing a safe, potent and cost-effective vector. Hyper-branched polymers have emerged as promising candi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::70a21d5ba7ae535274c7045e36b86da4