Treatment and prevention of intraepithelial neoplasia: An important target for accelerated new agent development: Recommendations of the American association for cancer research Task force on the Treatment and Prevention of intraepithelial neoplasia

Autor: O’Shaughnessy, JA, Kelloff, GJ, Gordon, GB, Dannenberg, AJ, Hong, WK, Fabian, CJ, Sigman, CC, Bertagnolli, MM, Stratton, SP, Lam, S, Nelson, WG, Meyskens, FL, Alberts, DS, Follen, M, Rustgi, AK, Papadimitrakopoulou, V, Scardino, PT, Gazdar, AF, Wattenberg, LW, Sporn, MB, Sakr, WA, Lippman, SM, Von Hoff, DD

Publikováno v: O’Shaughnessy, JA; Kelloff, GJ; Gordon, GB; Dannenberg, AJ; Hong, WK; Fabian, CJ; et al.(2002). Treatment and prevention of intraepithelial neoplasia: An important target for accelerated new agent development: Recommendations of the American association for cancer research Task force on the Treatment and Prevention of intraepithelial neoplasia. Clinical Cancer Research, 8(2), 314-346. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/49h1n5nx

Precancer or intraepithelial neoplasia (IEN) is a noninvasive lesion that has genetic abnormalities, loss of cellular control functions, and some phenotypic characteristics of invasive cancer and that predicts for a substantial likelihood of developi

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http://www.escholarship.org/uc/item/49h1n5nx

The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.

Autor: Reddy NM, Suryanaraya V, Yates MS, Kleeberger SR, Hassoun PM, Yamamoto M, Liby KT, Sporn MB, Kensler TW, Reddy SP, Reddy, Narsa M, Suryanaraya, Vegiraju, Yates, Melinda S, Kleeberger, Steven R, Hassoun, Paul M, Yamamoto, Masayuki, Liby, Karen T, Sporn, Michael B, Kensler, Thomas W, Reddy, Sekhar P

Publikováno v: American Journal of Respiratory & Critical Care Medicine; Nov2009, Vol. 180 Issue 9, p867-874, 8p

Role of raloxifene in breast cancer prevention in postmenopausal women: clinical evidence and potential mechanisms of action.

Autor: Sporn MB (AUTHOR), Dowsett SA (AUTHOR), Mershon J (AUTHOR), Bryant HU (AUTHOR)

Publikováno v: Clinical Therapeutics. Jun2004, Vol. 26 Issue 6, p830-840. 11p.

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts.

Autor: Colletta, AA, Wakefield, LM, Howell, FV, van Roozendaal, KE, Danielpour, D, Ebbs, SR, Sporn, MB, Baum, M, Colletta, A A, Wakefield, L M, Howell, F V, van Roozendaal, K E, Ebbs, S R, Sporn, M B

Publikováno v: British Journal of Cancer; Sep1990, Vol. 62 Issue 3, p405-409, 5p

Transforming growth factor-β: possible roles in carcinogenesis*

Autor: Roberts, AB, Thompson, NL, Heine, U, Flanders, C, Sporn, MB

Publikováno v: British Journal of Cancer; December 1988, Vol. 57 Issue: 6 p594-600, 7p