Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B

Autor: Spitsin, S. V., Farber, J. L., Bertovich, M., Moehren, G., Koprowski, H., Michaels, F. H.

BACKGROUND: The production of nitric oxide by type II inducible nitric oxide synthase (type II NOS) gene is controlled at least in part by transcriptional activation. Although the murine and human type II NOS genes share significant sequence homology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b761709ea21d0f5109253fda1efb8066
https://europepmc.org/articles/PMC2230078/

Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid

Autor: Spitsin, S. V., Scott, G. S., Kean, R. B., Mikheeva, T., Hooper, D. C.

Publikováno v: Neuroscience Letters; 2000, Vol. 292 Issue: 2 p137-141, 5p

Induction of the immune response to Legionella pneumophila cytolysin by monoclonal anti-idiotypic antibodies

Autor: Spitsin, S. V., Drobyshevskaya, E. I., Barkhatova, O. I., Yury Belyi, Tartakovsky, I. S., Nesterenko, V. G.

Publikováno v: Scopus-Elsevier

A panel of mAb (IgG1, IgG3, IgM) against Legionella pneumophila cytolysin (CL)-protease of 37 kDa was obtained. Subtyping of L. pneumophila strains of serogroup 1 by using mAb against CL (mAb-CL) was carried out. The results of comparative analysis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a199a67e32ae5844b98dd50774f3d637
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026040950&partnerID=MN8TOARS

Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine.

Autor: Yusibov V; Biotechnology Foundation Laboratories at Thomas Jefferson University, 1020 Locust Street, Room 346 JAH, Philadelphia, PA 19107, USA., Hooper DC, Spitsin SV, Fleysh N, Kean RB, Mikheeva T, Deka D, Karasev A, Cox S, Randall J, Koprowski H

Publikováno v: Vaccine [Vaccine] 2002 Aug 19; Vol. 20 (25-26), pp. 3155-64.

The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity.

Autor: Kean RB; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107, USA., Spitsin SV, Mikheeva T, Scott GS, Hooper DC

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2000 Dec 01; Vol. 165 (11), pp. 6511-8.