Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Spitschak A"'
Autor:
Alf Spitschak, Prabir Dhar, Krishna P. Singh, Rosaely Casalegno Garduño, Shailendra K. Gupta, Julio Vera, Luca Musella, Nico Murr, Anja Stoll, Brigitte M. Pützer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Melanoma is a metastatic, drug-refractory cancer with the ability to evade immunosurveillance. Cancer immune evasion involves interaction between tumor intrinsic properties and the microenvironment. The transcription factor E2F1 is a key driver of tu
Externí odkaz:
https://doaj.org/article/c657325e04404d39822a0b0f1f23ff5d
Akademický článek
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Autor:
Stubert, Johannes, Szewczyk, Marlen, Spitschak, Alf, Knoll, Susanne, Richter, Dagmar-Ulrike, Pützer, Brigitte M.
Publikováno v:
In Placenta 15 January 2020 90:109-117
Autor:
Spitschak, Alf1 (AUTHOR), Gupta, Shailendra2 (AUTHOR), Singh, Krishna P.2 (AUTHOR), Logotheti, Stella1 (AUTHOR), Pützer, Brigitte M.1,3 (AUTHOR) brigitte.puetzer@med.uni-rostock.de
Publikováno v:
Pharmaceutics. Jan2023, Vol. 15 Issue 1, p83. 26p.
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 83 (2022)
Cancer cells have a remarkable ability to evade recognition and destruction by the immune system. At the same time, cancer has been associated with chronic inflammation, while certain autoimmune diseases predispose to the development of neoplasia. Al
Externí odkaz:
https://doaj.org/article/ad0b04cfaba54d56a10813709ec40325
Autor:
Fürst, Katharina, Steder, Marc, Logotheti, Stella, Angerilli, Alessandro, Spitschak, Alf, Marquardt, Stephan, Schumacher, Toni, Engelmann, David, Herchenröder, Ottmar, Rupp, Ralph A.W., Pützer, Brigitte M.
Publikováno v:
In Cancer Letters 1 February 2019 442:299-309
Autor:
Stella Logotheti, Christin Richter, Nico Murr, Alf Spitschak, Stephan Marquardt, Brigitte M. Pützer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The transcription factor p73 is a structural and functional homolog of TP53, the most famous and frequently mutated tumor-suppressor gene. The TP73 gene can synthesize an overwhelming number of isoforms via splicing events in 5′ and 3′ ends and a
Externí odkaz:
https://doaj.org/article/9dc88289fc5d4874883451a05711f46d
Autor:
Christin Richter, Stephan Marquardt, Fanghua Li, Alf Spitschak, Nico Murr, Berdien A. H. Edelhäuser, George Iliakis, Brigitte M. Pützer, Stella Logotheti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Bladder cancer progression has been associated with dysfunctional repair of double-strand breaks (DSB), a deleterious type of DNA lesions that fuel genomic instability. Accurate DSB repair relies on two distinct pathways, homologo
Externí odkaz:
https://doaj.org/article/22f82b4a638340d89026eb39128394df
Publikováno v:
In Seminars in Cancer Biology December 2018 53:90-109
Autor:
Faiz M. Khan, Stephan Marquardt, Shailendra K. Gupta, Susanne Knoll, Ulf Schmitz, Alf Spitschak, David Engelmann, Julio Vera, Olaf Wolkenhauer, Brigitte M. Pützer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Deregulation of E2F family transcription factors is associated with cancer progression and metastasis. Here, the authors construct a map of the regulatory network around the E2F family, and using gene expression profiles, identify tumour type-specifi
Externí odkaz:
https://doaj.org/article/6feb9a206c964085ae20896ed0722b38