The farnesoid X receptor activates transcription independently of RXR at non-canonical response elements.

Autor: van der Veen SW; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands., Dijkstra JJ; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Geert Grooteplein 26-28, 6525GA Nijmegen, The Netherlands.; Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands., Willemsen ECL; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands., Houtman R; Precision Medicine Lab, Antoni van Leeuwenhoek Building, Kloosterstraat 9, 5349AE Oss, The Netherlands., Milona A; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands.; The Francis Crick Institute, 1 Midland Road, London NW11AT, UK., Marchet N; Institute of Biochemistry, University of Innsbruck, Innrain 80-82, Innsbruck, Tirol A-6020, Austria., Spit M; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands., Hollman D; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands., Zwartkruis FJT; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands., Vermeulen M; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Geert Grooteplein 26-28, 6525GA Nijmegen, The Netherlands.; Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands., Ramos Pittol JM; Institute of Biochemistry, University of Innsbruck, Innrain 80-82, Innsbruck, Tirol A-6020, Austria., van Mil SWC; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Stratenum Building, Universiteitsweg 100, 3584CG Utrecht, The Netherlands.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Dec 09. Date of Electronic Publication: 2024 Dec 09.

Immunomodulatory Functions of TNF-Related Apoptosis-Inducing Ligand in Type 1 Diabetes.

Autor: Fogarasi, Marton¹ (AUTHOR) marton.fogarasi@icfundeni.ro, Dima, Simona^1,2 (AUTHOR)

Publikováno v: Cells (2073-4409). Oct2024, Vol. 13 Issue 20, p1676. 17p.

Tumour suppressor RNF43 is a

Autor: 8) Koo, B-K, Spit, M. Jordens, I, Low, T.Y, Stange, D.E, van de Wetering, M, van Es, J.H, Mohammed, S, Heck, A.J.R, Maurice, M.M. and Hans Clevers, 8) Koo, B-K., Spit, M. Jordens, I., Low, T.Y., Stange, D.E., van de Wetering, M., van Es, J.H., Mohammed, S., Heck, A.J.R., Maurice, M.M., Hans Clevers

Publikováno v: Nature.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=erc_________::145fe25ef19fbd2c2be78d0910654e0f

RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.

Autor: Spit M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Fenderico N; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Jordens I; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Radaszkiewicz T; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Lindeboom RG; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands., Bugter JM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Cristobal A; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Ootes L; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., van Osch M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Janssen E; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Boonekamp KE; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Hanakova K; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Potesil D; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Zdrahal Z; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Boj SF; Hubrecht Organoid Technology, Utrecht, The Netherlands., Medema JP; Laboratory for Experimental Oncology and Radiobiology and Oncode Institute, Center for Experimental and Molecular Medicine, Amsterdam UMC, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Koo BK; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Vermeulen M; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands., Maurice MM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Publikováno v: The EMBO journal [EMBO J] 2020 Sep 15; Vol. 39 (18), pp. e103932. Date of Electronic Publication: 2020 Aug 10.

Advancements in Research and Treatment Applications of Patient-Derived Tumor Organoids in Colorectal Cancer.

Autor: van der Graaff, Denise¹ (AUTHOR), Seghers, Sofie^1,2 (AUTHOR) sofie.seghers@uantwerpen.be, Vanclooster, Pieterjan¹ (AUTHOR), Deben, Christophe² (AUTHOR), Vandamme, Timon^1,2 (AUTHOR), Prenen, Hans^1,2 (AUTHOR)

Publikováno v: Cancers. Aug2024, Vol. 16 Issue 15, p2671. 20p.