Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Spiridon Papapetropoulos"'
Autor:
Timothy G Lesnick, Eric J Sorenson, J Eric Ahlskog, John R Henley, Lina Shehadeh, Spiridon Papapetropoulos, Demetrius M Maraganore
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1449 (2008)
We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susce
Externí odkaz:
https://doaj.org/article/3b5a3111f6bb41f7a4bd4c7ea45fa921
Autor:
Timothy G Lesnick, Spiridon Papapetropoulos, Deborah C Mash, Jarlath Ffrench-Mullen, Lina Shehadeh, Mariza de Andrade, John R Henley, Walter A Rocca, J Eric Ahlskog, Demetrius M Maraganore
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e98 (2007)
While major inroads have been made in identifying the genetic causes of rare Mendelian disorders, little progress has been made in the discovery of common gene variations that predispose to complex diseases. The single gene variants that have been sh
Externí odkaz:
https://doaj.org/article/69ad72c5c8eb41c0bc042f38bd2f619e
Autor:
Georgina Tzanakaki, Themistoklis Karpathios, Alexandra Guevara-Salcedo, Spiridon Papapetropoulos, Jenny Kremastinou, Fani Leontsini, Maria Papapetropoulou
Publikováno v:
Journal of Pediatric Infectious Diseases. :137-139
A case of a 5-year-old child with signs and symptoms of bacterial meningitis was admitted to the “Iatrikon Athinon” Medical Center, Athens, Greece. The isolated strain was identified as Neisseria lactamica. Susceptibility to penicillin, cefotaxim
Autor:
A. Buck, Paul Alan Cox, T. E. Johnson, Spiridon Papapetropoulos, Sandra Anne Banack, John Pablo, Deborah C. Mash, Walter G. Bradley
Publikováno v:
Acta Neurologica Scandinavica. 120:216-225
Objective – The aim of this study was to screen for and quantify the neurotoxic amino acid β-N-methylamino-l-alanine (BMAA) in a cohort of autopsy specimens taken from Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), Huntington’s
FGF20and Parkinson's disease: No evidence of association or pathogenicity via α-synuclein expression
Autor:
Michael G. Heckman, Alex Rajput, J. Mark Gibson, Kristoffer Haugarvoll, Sarah Lincoln, Mei Yue, Justus C. Dachsel, Alexandra I. Soto, Ryan J. Uitti, Spiridon Papapetropoulos, Deborah C. Mash, Ali H. Rajput, Nancy N. Diehl, Jan O. Aasly, Christian Wider, Timothy Lynch, John Q. Trojanowski, Zbigniew K. Wszolek, Dennis W. Dickson, Matthew J. Farrer, Owen A. Ross
Publikováno v:
Movement Disorders. 24:455-459
Genetic variation in fibroblast growth factor 20 (FGF20) has been associated with risk of Parkinson's disease (PD). Functional evidence suggested the T allele of one SNP, rs12720208 C/T, altered PD risk by increasing FGF20 and α-synuclein protein le
Autor:
Spiridon Papapetropoulos, Haralabos P. Kalofonos, Martin Koltzenburg, Andreas A. Argyriou, Panagiotis Polychronopoulos
Publikováno v:
Critical Reviews in Oncology/Hematology. 66:218-228
Peripheral neuropathy is a well recognized toxicity of taxanes, usually resulting to dose modification and changes in the treatment plan. Taxanes produce a symmetric, axonal predominantly sensory distal neuropathy with less prominent motor involvemen
Publikováno v:
Acta Neurologica Scandinavica. 117:224-230
Painful limbs/moving extremities (PLME) is a disorder characterized by spontaneous, complex, slow (1-2 Hz) involuntary toe or finger movements. The movements that can be bilateral or unilateral are usually accompanied by pain in the affected limbs. P
Publikováno v:
European Neurology. 59:71-75
Retrocollis (RC) is a form of cervical dystonia (CD) that produces patterned, repetitive muscle contractions that result in neck extension. We performed a review of consecutive CD patients seen in our Division over a 15-year period. Out of 399 CD pat
Publikováno v:
Parkinsonism & Related Disorders. 13:308-311
Orthostatic hypotension (OH) in Parkinson's disease (PD) patients may be a significant source of morbidity and discomfort. Although peripheral ANS components have been associated with its development, central mechanisms are probably involved. The ins
Autor:
Spiridon Papapetropoulos
Publikováno v:
Neurochemistry International. 50:998-1003
The naturally occurring, non-essential amino acid beta-N-methylamino-L-alanine (BMAA) has been recently found in high concentrations in brain tissues of patients with tauopathies such as the Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex