Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Spiridione Garbisa"'
Publikováno v:
Molecules, Vol 15, Iss 9, Pp 6570-6579 (2010)
Resveratrol (trans-3,4',5-trihydroxystilbene) and quercetin (3,3’,4’,5,7-pentahydroxyflavone) are two naturally occurring polyphenols with the potential to exert beneficial health effects. Since their low bioavailability is a major obstacle to bi
Externí odkaz:
https://doaj.org/article/e1e8f27e312e4255857fcff7fa3ca68c
Autor:
Mario Zoratti, Ester Marotta, Spiridione Garbisa, Lucia Biasutto, Federico Rastrelli, Andrea Mattarei, Cristina Paradisi
Publikováno v:
Molecules, Vol 15, Iss 7, Pp 4722-4736 (2010)
The regioselective synthesis of several quercetin (3,3’,4’,5,7-pentahydroxy flavone) tetraesters bearing a single free OH on 5-C was achieved in good yield by proper choice of reaction conditions using common esterification procedures. Tetracetyl
Externí odkaz:
https://doaj.org/article/f0f265430020409c832cb5a6c0c4eab4
Autor:
Spiridione Garbisa, Andrea Mattarei, Anna Citta, Valentina Giorgio, Ildikò Szabò, Paolo Bernardi, Massimo Carraro, Lucia Biasutto, Mario Zoratti, Nicola Sassi, Cristina Paradisi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1817(7):1095-1106
The mitochondriotropic compound 7-O-(4-triphenylphosphoniumbutyl)quercetin iodide (Q-7BTPI) in the μM concentration range caused necrotic death of cultured cells by acting as a prooxidant, with generation of superoxide anion in the mitochondria. Ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db50edb84c914df3ca25a0d18e69f720
Publikováno v:
Open Environmental Sciences. 6:1-12
Protocols and results of case-control studies, pooled- and meta-analyses on the relationship between mobile phone use and risk of head tumours are critically analysed, and for each study strict elements necessary for evaluating its reliability are id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff148cb67e990213780773792ee3a41
https://doi.org/10.2174/1876325101206010001
https://doi.org/10.2174/1876325101206010001
Autor:
Christian Durante, Andrea Mattarei, Spiridione Garbisa, Armando Gennaro, Giancarlo Sandonà, Cristina Paradisi, Lucia Biasutto, Nicola Sassi, Mario Zoratti, Ester Marotta
Publikováno v:
European Journal of Organic Chemistry. 2011:5577-5586
Mitochondria-targeted redox-active polyphenol derivatives are being developed to affect redox processes in the organelles and as tools either to protect cells from oxidative damage or to precipitate their death. The properties of such compounds may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8128e0ab210c8fe5a0ab8394d744a09
https://doi.org/10.1002/ejoc.201100573
https://doi.org/10.1002/ejoc.201100573
Autor:
Spiridione Garbisa, Lucia Biasutto, Cristina Paradisi, Antonio Toninello, Ester Marotta, Paola Cattelan, Andrea Mattarei, Mario Zoratti, Nicola Sassi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(2):189-196
Mitochondria-targeted polyphenols are being developed with the intent to intervene on the levels of reactive oxygen species (ROS) in mitochondria. Polyphenols being more than just anti-oxidants, the interaction of these derivatives with the organelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ed48a3147e976639d76df04bdd5d02
Autor:
Lucia Biasutto, Fiorella Calabrese, Francesco Piazza, Spiridione Garbisa, Francesco Cinetto, Carmela Gurrieri, Anna Cabrelle, Marianna Gnoato, Barbara Montini, Raffaele Niero, Monica Facco, Cristina Gattazzo, Enrico Brunetta, Carlo Agostini, Gianpietro Semenzato
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 332:785-794
Glycogen synthase kinase (GSK)-3 modulates the production of inflammatory cytokines. Because bleomycin (BLM) causes lung injury, which is characterized by an inflammatory response followed by a fibrotic degeneration, we postulated that blocking GSK-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4476d33f4929902f6ef8003257ec0996
https://doi.org/10.1124/jpet.109.153049
https://doi.org/10.1124/jpet.109.153049
Autor:
Lucia Biasutto, Mauro Fallica, Cristina Paradisi, Mario Zoratti, Spiridione Garbisa, Ester Marotta, Andrea Mattarei, Alice Bradaschia
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6721-6724
We report the development of a chemical modification method of general applicability to polyphenols, which increases solubility to influence absorption. Glucosyl groups were added to the resveratrol kernel via a succinate linker, yielding 3,4′,5-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6226db3b1ea0e4c5576120523492d625
https://doi.org/10.1016/j.bmcl.2009.09.114
https://doi.org/10.1016/j.bmcl.2009.09.114
Autor:
Michele Antonello, Gian Paolo Rossi, Italia Papparella, Spiridione Garbisa, Giulio Ceolotto, Andrea Semplicini, Domenico Montemurro
Publikováno v:
The Journal of Nutrition. 138:1596-1601
We previously documented a clear-cut antihypertensive effect of green teat extract (GTE), which was associated with correction of endothelial dysfunction and prevention of left ventricular hypertrophy in an angiotensin II (Ang II)-dependent model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b7ced1f788a9a529c968b5e342bfba0
https://doi.org/10.1093/jn/138.9.1596
https://doi.org/10.1093/jn/138.9.1596
Publikováno v:
Acta Pharmacologica Sinica. 29:853-860
Aim: Tetrahydrocurcumin (THC) is an active metabolite of curcumin. It has been reported to have similar pharmacological activity to curcumin. The proteases that participate in extracellular matrix (ECM) degradation are involved in cancer cell metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91c9d3f39d5ff7739fc757d517cf72aa
https://doi.org/10.1111/j.1745-7254.2008.00792.x
https://doi.org/10.1111/j.1745-7254.2008.00792.x