Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Spindle localization"'
Autor:
Quentin D. Sprengelmeyer, John E. Pool
Publikováno v:
Ecology and Evolution, Vol 11, Iss 21, Pp 15364-15376 (2021)
Understanding the genetic properties of adaptive trait evolution is a fundamental crux of biological inquiry that links molecular processes to biological diversity. Important uncertainties persist regarding the genetic predictability of adaptive trai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f568b34e8fcd79530a7fe6a3e41ec864
https://doaj.org/article/7f5988a9ffe44b64bb3f5c32f5009a35
https://doaj.org/article/7f5988a9ffe44b64bb3f5c32f5009a35
Autor:
Chiara Lara Castellazzi, Oscar Reina, Carolina Segura-Morales, Nicolás Bellora, Rosa Pascual, Manja Omerzu, Madelon M. Maurice, Alba Millanes-Romero, Raúl Méndez, Eduardo Eyras, Eulàlia Belloc
Publikováno v:
RNA (New York, N.Y.).
Transition through cell cycle phases requires temporal and spatial regulation of gene expression to ensure accurate chromosome duplication and segregation. This regulation involves dynamic reprogramming of gene expression at multiple transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11344b85da4435fb7d048cf08282bdc4
https://pubmed.ncbi.nlm.nih.gov/33323527
https://pubmed.ncbi.nlm.nih.gov/33323527
The role of the neck-linker (NL) element in regulating the functions of bi-directional kinesins is unknown. We report that replacing the NL of the bi-directional kinesin-5 Cin8 with sequences from plus-end directed kinesins produces non-functional Ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67dd11770f093e5c2e2593e72cc0ca45
https://doi.org/10.1101/2020.05.27.118430
https://doi.org/10.1101/2020.05.27.118430
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES. 25(10)
Chromosome segregation requires the formation of a bipolar spindle. The timely bipolarization of the acentrosomal spindle during meiosis I in mouse oocytes depends on the antiparallel microtubule crosslinker Prc1. How Prc1 is regulated in oocytes rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc317b87404bb80721a9d1d3e1956e2b
https://pubmed.ncbi.nlm.nih.gov/32865279
https://pubmed.ncbi.nlm.nih.gov/32865279
Autor:
Alina Goldstein, Mardo Kõivomägi, Larisa Gheber, Darya Goldman, Ervin Valk, Haim Judah, Nurit Siegler, Mart Loog
Publikováno v:
Cellular and Molecular Life Sciences
The bipolar kinesin-5 motors perform essential functions in mitotic spindle dynamics. We previously demonstrated that phosphorylation of at least one of the Cdk1 sites in the catalytic domain of the Saccharomyces cerevisiae kinesin-5 Cin8 (S277, T285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc28d8283c27bafed8e913c9e403adfe
https://doi.org/10.1007/s00018-017-2523-z
https://doi.org/10.1007/s00018-017-2523-z
The dynamic process of mitotic spindle assembly depends on multitudes of inter-dependent interactions involving kinetochores (KTs), microtubules (MTs), spindle pole bodies (SPBs), and molecular motors. Before forming the mitotic spindle, multiple vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66127a87ff26f9daa9ffdd51dda89eb8
https://doi.org/10.1101/690651
https://doi.org/10.1101/690651
Autor:
Xiao Guo, Biying Yang, Chuanmao Zhang, Mengjie Sun, Boyan Zhang, Qing Jiang, Jia Luo, Guangwei Xin
Publikováno v:
The Journal of biological chemistry. 294(14)
In all eukaryotes, a functional mitotic spindle is essential for distributing duplicated chromosomes into daughter cells. Mitotic spindle assembly involves highly ordered arrangement of microtubules (MTs). The Augmin protein complex recruits γ-tubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f18f672079e8a7e79e2305d7e7d070
https://pubmed.ncbi.nlm.nih.gov/30723163
https://pubmed.ncbi.nlm.nih.gov/30723163
Autor:
Mark W. Richards, Nicolas Huguenin-Dezot, Richard Bayliss, Manjeet Mukherjee, Sarah R. Sabir, Jason W. Chin, James R. Ault, Andrew M. Fry, Laura O'Regan, Anastasia Zhuravleva, Josephina Sampson
Publikováno v:
Science Signaling. 11
Hsp72 is a member of the 70-kD heat shock family of molecular chaperones (Hsp70s) that comprise a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD) connected by a linker that couples the exchange of adenosine diphosphate (ADP) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839e38e8e645593f67f9730d4401ae02
https://doi.org/10.1126/scisignal.aao2464
https://doi.org/10.1126/scisignal.aao2464
Autor:
Tomasz Gambin, Stylianos E. Antonarakis, Jennifer McEvoy-Venneri, Najmeh Ahangari, Kiely N. James, Justyna Iwaszkiewicz, Amera Elbadawy, Shalini N. Jhangiani, Zeynep Coban Akdemir, Asbjørg Stray-Pedersen, Valentina Stanley, Federico Santoni, Vincent Zoete, Paul Hoff Backe, Reza Maroofian, Damir Musaev, Denice Belandres, Joseph G. Gleeson, Arvid Heiberg, Periklis Makrythanasis, James R. Lupski, Iman G Mahmoud, Mohammad Doosti, Laila Selim, Maha S. Zaki, Hanan Hamamy, Fatemeh Tara, Michel Guipponi, Ehsan Ghayoor Karimiani, Hanne Sørmo Sorte
Publikováno v:
European Journal of Human Genetics
European journal of human genetics, vol. 26, no. 3, pp. 330-339
European journal of human genetics, vol. 26, no. 3, pp. 330-339
Kinesin proteins are critical for various cellular functions such as intracellular transport and cell division, and many members of the family have been linked to monogenic disorders and cancer. We report eight individuals with intellectual disabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac4519c9762812054ab57ca69ceebe8
http://hdl.handle.net/10852/71698
http://hdl.handle.net/10852/71698
Autor:
Chang Suk Suh, Seul Ki Kim, Seok Hyun Kim, Hyun Sun Kong, Jaewang Lee, Eun Jung Kim, Jung Ryeol Lee, Hye Won Youm
Publikováno v:
BioMed Research International, Vol 2018 (2018)
BioMed Research International
BioMed Research International
In vitro follicle growth (IVFG) is an emerging fertility preservation technique, which can obtain fertilizable oocytes from an in vitro culture system in female. This study aimed to compare efficiency of the most widely used two-dimensional follicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb9faf027295a80e98fd09fec88f8a3
https://doaj.org/article/e04734125cf54a439e30833843f84377
https://doaj.org/article/e04734125cf54a439e30833843f84377