Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Spike(S)"'
Autor:
Li Zhang, Wei Miao, Mo Zhou, Miao Lin, Changyao Fu, Zhi Wu, Xinnuo Lei, Jialong Xu, Shinuo Cao, Shanyuan Zhu
Publikováno v:
Veterinary Sciences, Vol 11, Iss 11, p 533 (2024)
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that infect pigs’ intestinal epithelial cells, causing high morbidity and mortality. Due to the rapid mutation of PEDV, vaccine efficacy is uncertain, prompting exploration o
Externí odkaz:
https://doaj.org/article/ffeddc6e372e4fd3a6967e39d63c0f09
Autor:
Shohei Minami, Tomohiro Kotaki, Yusuke Sakai, Shinya Okamura, Shiho Torii, Chikako Ono, Daisuke Motooka, Rina Hamajima, Ryotaro Nouda, Jeffery A. Nurdin, Moeko Yamasaki, Yuta Kanai, Hirotaka Ebina, Yusuke Maeda, Toru Okamoto, Taro Tachibana, Yoshiharu Matsuura, Takeshi Kobayashi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes several host proteases to cleave the spike (S) protein to enter host cells. SARS-CoV-2 S protein is cleaved into S1 and S2 subunits by furin, which is closely involved in t
Externí odkaz:
https://doaj.org/article/52bcfaa75fde4976b2cff269b2a83cf6
Autor:
Nqobile Monate Mkolo, Clarissa Marcelle Naidoo, Rose Kadye, Chikwelu Lawrence Obi, Benson Chucks Iweriebor, Oyinlola Oluwunmi Olaokun, Earl Prinsloo, Muhammad Sulaiman Zubair
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 821 (2024)
The expected progress in SARS-CoV-2 vaccinations, as anticipated in 2020 and 2021, has fallen short, exacerbating global disparities due to a lack of universally recognized “safe and effective” vaccines. This study focuses on extracts of South Af
Externí odkaz:
https://doaj.org/article/c4891ab018c740dc96843909ba0625e0
Autor:
Mohamad Ammar Ayass, Trivendra Tripathi, Natalya Griko, Victor Pashkov, Jun Dai, Jin Zhang, Fabian C. Herbert, Ramya Ramankutty Nair, Tutku Okyay, Kevin Zhu, Jeremiah J. Gassensmith, Lina Abi-Mosleh
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background The paucity of SARS-CoV-2-specific virulence factors has greatly hampered the therapeutic management of patients with COVID-19 disease. Although available vaccines and approved therapies have shown tremendous benefits, the continu
Externí odkaz:
https://doaj.org/article/31524c5489f54663a03c1738ff62c20b
Autor:
Shih-Han Ko, Wan-Yu Chen, Shih-Chieh Su, Hsiu-Ting Lin, Feng-Yi Ke, Kang-Hao Liang, Fu-Fei Hsu, Monika Kumari, Chi-Yu Fu, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harbor diverse spike (S) protein sequences, which can greatly influence the efficacies of therapeutics. Therefore, it would be of great value to develop
Externí odkaz:
https://doaj.org/article/738750f514c14a22a2f66f17d012271e
Autor:
Petia Genova-Kalou, Georgi Dyankov, Hristo Kisov, Vihar Mankov, Evdokiya Hikova, Stefka Krumova, Nikola Malinowski
Publikováno v:
Problems of Infectious and Parasitic Diseases, Vol 50, Iss 3 (2023)
Background: The World Health Organization admitted that the vaccination against Covid 19 limited the deaths, but not the spread of the disease. This requires a method allowing a specific, rapid and accurate diagnosis of the disease. We report a SPR a
Externí odkaz:
https://doaj.org/article/19b6cc83af86497d9d4eee85e56b044b
Autor:
Jared Sheehan, Caleb M. Ardizzone, Mayank Khanna, Amber J. Trauth, Michael E. Hagensee, Alistair J. Ramsay
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1720 (2023)
SARS-CoV-2 mRNA vaccines are administered as effective prophylactic measures for reducing virus transmission rates and disease severity. To enhance the durability of post-vaccination immunity and combat SARS-CoV-2 variants, boosters have been adminis
Externí odkaz:
https://doaj.org/article/50ecb1ccc85e4587801196deb66099f2
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread globally, a series of vaccines, antibodies and drugs have been developed to combat coronavirus disease 2019 (COVID-19). High specific antibodies are powerful
Externí odkaz:
https://doaj.org/article/354d66cc86ee4f88aadc4fab2d34ed13
Autor:
Ahmed S. Alshrari, Shuaibu A. Hudu, Mohd Imran, Syed Mohammed Basheeruddin Asdaq, Alreshidi M. Ali, Syed Imam Rabbani
Publikováno v:
Journal of Infection and Public Health, Vol 15, Iss 1, Pp 123-131 (2022)
More than 125 million confirmed cases of COVID-19 have been reported globally with rising cases in all countries since the first case was reported. A vaccine is the best measure for the effective prevention and control of COVID-19. There are more tha
Externí odkaz:
https://doaj.org/article/4b45edbd0dfe447f85206371221ff20c
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