Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.

Autor: O'Brien E; a Department of Pathology and., Spiess PC; a Department of Pathology and., Habibovic A; a Department of Pathology and., Hristova M; a Department of Pathology and., Bauer RA; a Department of Pathology and., Randall MJ; a Department of Pathology and., Poynter ME; b Department of Medicine , College of Medicine, University of Vermont , Burlington , VT , USA., van der Vliet A; a Department of Pathology and.

Publikováno v: Journal of immunotoxicology [J Immunotoxicol] 2016; Vol. 13 (2), pp. 191-7. Date of Electronic Publication: 2015 Apr 15.

Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts.

Autor: Macura SL; Department of Pathology, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405-0068, USA. brooke.mossman@uvm.edu., Steinbacher JL, Macpherson MB, Lathrop MJ, Sayan M, Hillegass JM, Beuschel SL, Perkins TN, Spiess PC, van der Vliet A, Butnor KJ, Shukla A, Wadsworth M, Landry CC, Mossman BT

Publikováno v: BMC cancer [BMC Cancer] 2013 Sep 11; Vol. 13, pp. 400. Date of Electronic Publication: 2013 Sep 11.

Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1.

Autor: Randall MJ; Department of Pathology, College of Medicine, University of Vermont, Burlington, VT 05405, USA., Spiess PC, Hristova M, Hondal RJ, van der Vliet A

Publikováno v: Redox biology [Redox Biol] 2013 Feb 22; Vol. 1, pp. 265-75. Date of Electronic Publication: 2013 Feb 22 (Print Publication: 2013).

Proteomic profiling of acrolein adducts in human lung epithelial cells.

Autor: Spiess PC; Department of Pathology, University of Vermont, Burlington, VT 05405, USA., Deng B, Hondal RJ, Matthews DE, van der Vliet A

Publikováno v: Journal of proteomics [J Proteomics] 2011 Oct 19; Vol. 74 (11), pp. 2380-94. Date of Electronic Publication: 2011 Jun 17.

Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis.

Autor: Spiess PC; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, California, USA. pcspiess@ucdavis.edu, Morin D, Jewell WT, Buckpitt AR

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2008 May; Vol. 21 (5), pp. 1074-85. Date of Electronic Publication: 2008 Apr 17.