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Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy.
Autor:
Karbon G; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Schuler F; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Braun VZ; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Eichin F; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Haschka M; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Drach M; Dermatology, General Hospital, University Hospital Vienna, Vienna, Austria., Sotillo R; German Cancer Research Center (DKFZ), Division of Molecular Thoracic Oncology, Heidelberg, Germany., Geley S; Institute for Pathophysiology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands., Tijhuis AE; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands., Villunger A; Institute for Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria. andreas.villunger@i-med.ac.at.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria. andreas.villunger@i-med.ac.at.
Publikováno v:
EMBO reports [EMBO Rep] 2024 Jun; Vol. 25 (6), pp. 2743-2772. Date of Electronic Publication: 2024 May 28.
Autor:
Spierings DC; Department of Physics and CQIQC, University of Toronto, Toronto, Ontario M5S 1A7, Canada., Thywissen JH; Department of Physics and CQIQC, University of Toronto, Toronto, Ontario M5S 1A7, Canada., Steinberg AM; Department of Physics and CQIQC, University of Toronto, Toronto, Ontario M5S 1A7, Canada.
Publikováno v:
Physical review letters [Phys Rev Lett] 2024 Apr 26; Vol. 132 (17), pp. 173401.
Autor:
Gliech CR; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Yeow ZY; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Tapias-Gomez D; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Yang Y; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Huang Z; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Tijhuis AE; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, AV, 9713, The Netherlands., Chung G; Oncology Research, Amgen Research, Thousand Oaks, CA, 91320, USA., Tamayo N; Medicinal Chemistry, Amgen Research, Thousand Oaks, CA, 91320, USA., Bahrami-Nejad Z; Genome Analysis Unit, Amgen Research, South San Francisco, CA, 94084, USA., Collins P; Genome Analysis Unit, Amgen Research, South San Francisco, CA, 94084, USA., Nguyen TT; Genome Analysis Unit, Amgen Research, South San Francisco, CA, 94084, USA., Plata Stapper A; Center for Research Acceleration by Digital Innovation, Amgen Research, South San Francisco, CA, 94084, USA., Hughes PE; Oncology Research, Amgen Research, Thousand Oaks, CA, 91320, USA., Payton M; Oncology Research, Amgen Research, Thousand Oaks, CA, 91320, USA., Holland AJ; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. aholland@jhmi.edu.
Publikováno v:
The EMBO journal [EMBO J] 2024 Mar; Vol. 43 (5), pp. 666-694. Date of Electronic Publication: 2024 Jan 26.
Autor:
Saba KH; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Difilippo V; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Kovac M; Bone Tumour Reference Centre at the Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland.; Faculty of Informatics and Information Technologies, Slovak University of Technology, Bratislava, Slovakia., Cornmark L; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Magnusson L; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Nilsson J; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Bidgoli M; Department of Clinical Genetics and Pathology, Laboratory Medicine, Medical Services, Skåne University Hospital, Lund, Sweden., Jonson T; Department of Clinical Genetics and Pathology, Laboratory Medicine, Medical Services, Skåne University Hospital, Lund, Sweden., Sumathi VP; Department of Musculoskeletal Pathology, Royal Orthopaedic Hospital, Birmingham, UK., Brosjö O; Department of Orthopedics, Karolinska University Hospital, Stockholm, Sweden., Staaf J; Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Styring E; Department of Orthopedics, Lund University, Skåne University Hospital, Lund, Sweden., Nathrath M; Children's Cancer Research Centre and Department of Pediatrics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.; Department of Pediatric Oncology, Klinikum Kassel, Kassel, Germany., Baumhoer D; Bone Tumour Reference Centre at the Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland., Nord KH; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden.
Publikováno v:
The Journal of pathology [J Pathol] 2024 Feb; Vol. 262 (2), pp. 147-160. Date of Electronic Publication: 2023 Nov 27.
Autor:
Spierings DC; Centre for Quantum Information and Quantum Control, Department of Physics, University of Toronto, 60 St. George Street, Toronto, Ontario M5S 1A7, Canada.; Canadian Institute for Advanced Research, MaRS Centre, West Tower 661 University Ave., Toronto, Ontario M5G 1M1, Canada., Steinberg AM; Centre for Quantum Information and Quantum Control, Department of Physics, University of Toronto, 60 St. George Street, Toronto, Ontario M5S 1A7, Canada.; Canadian Institute for Advanced Research, MaRS Centre, West Tower 661 University Ave., Toronto, Ontario M5G 1M1, Canada.
Publikováno v:
Physical review letters [Phys Rev Lett] 2021 Sep 24; Vol. 127 (13), pp. 133001.
Autor:
Phan TP; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Maryniak AL; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Boatwright CA; Johns Hopkins University, Baltimore, MD, USA., Lee J; Johns Hopkins University, Baltimore, MD, USA., Atkins A; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Tijhuis A; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bazzi H; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department of Dermatology and Venereology, University Hospital of Cologne, Köln, Germany., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Jordan PW; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Stracker TH; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Holland AJ; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publikováno v:
The EMBO journal [EMBO J] 2021 Jan 04; Vol. 40 (1), pp. e106118. Date of Electronic Publication: 2020 Nov 23.
Autor:
Sladky VC; Institute of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Knapp K; Institute of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Szabo TG; Institute of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Braun VZ; Institute of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Bongiovanni L; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Westendorp B; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Curinha A; Institute of Pathophysiology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria., Stojakovic T; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Timelthaler G; Institute for Cancer Research, Internal Medicine I, Medical University of Vienna, Vienna, Austria., Tsuchia K; Department of Gastroenterology & Hepatology, Musashino Red Cross Hospital, Tokyo, Japan., Pinter M; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Semmler G; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., de Bruin A; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.; Department Pediatrics, University Medical Center Groningen, University Groningen, Groningen, The Netherlands., Reiberger T; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Rohr-Udilova N; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Villunger A; Institute of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Publikováno v:
EMBO reports [EMBO Rep] 2020 Dec 03; Vol. 21 (12), pp. e50893. Date of Electronic Publication: 2020 Nov 23.
Autor:
Saba KH; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Cornmark L; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Hofvander J; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Magnusson L; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., Nilsson J; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Staaf J; Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden., Brosjö O; Department of Orthopedics, Karolinska University Hospital, Stockholm, Sweden., Sumathi VP; Department of Musculoskeletal Pathology, Royal Orthopaedic Hospital, Birmingham, UK., Lam SW; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Szuhai K; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Bovée JV; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Kovac M; Bone Tumour Reference Centre at the Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland., Baumhoer D; Bone Tumour Reference Centre at the Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland., Styring E; Department of Orthopedics, Lund University, Skåne University Hospital, Lund, Sweden., Nord KH; Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden.
Publikováno v:
The journal of pathology. Clinical research [J Pathol Clin Res] 2020 Oct; Vol. 6 (4), pp. 231-237. Date of Electronic Publication: 2020 Jun 16.
Autor:
Schukken KM; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Lin YC; Goettingen Center for Molecular Biosciences and University Medical Center, Goettingen, Germany., Bakker PL; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Schubert M; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Preuss SF; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Simon JE; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Storchova Z; Department of Molecular Genetics, University of Kaiserslautern, Germany., Colomé-Tatché M; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.; Institute of Computational Biology, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany., Bastians H; Goettingen Center for Molecular Biosciences and University Medical Center, Goettingen, Germany., Spierings DC; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands f.foijer@umcg.nl.
Publikováno v:
Life science alliance [Life Sci Alliance] 2020 Jan 24; Vol. 3 (2). Date of Electronic Publication: 2020 Jan 24 (Print Publication: 2020).