Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Spicer, James Frederick"'
Autor:
Pellizzari, Giulia, Hoskin, Coran Michael, Crescioli, Silvia, Mele, Silvia, Gotovina, Jelena, Chiaruttini, Giulia, Bianchini, Rodolfo, Ilieva, Kristina Maksimova, Bax, Heather Jane, Papa, Sophie Elinor, Lacy, Katie E., Jensen-Jarolim, Erika, Tsoka, Sophia, Josephs, Debra Hannah, Spicer, James Frederick, Karagiannis, Sophia N
Publikováno v:
Pellizzari, G, Hoskin, C M, Crescioli, S, Mele, S, Gotovina, J, Chiaruttini, G, Bianchini, R, Ilieva, K M, Bax, H J, Papa, S E, Lacy, K E, Jensen-Jarolim, E, Tsoka, S, Josephs, D H, Spicer, J F & Karagiannis, S N 2019, ' IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states ', EBioMedicine, vol. 43, EBIOM2073, pp. 67-81 . https://doi.org/10.1016/j.ebiom.2019.03.080
Background Antibody Fc-driven engagement of macrophages is critical for evoking cellular activation and effector functions and influencing tumour-associated macrophage (TAM) recruitment. We previously reported that IgE class antibodies promote restri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2761::4d3d8c9fa6e4ef0a67c789b0fe1cd545
https://kclpure.kcl.ac.uk/ws/files/108045245/Pellizzari_et_al_Accepted_Ms_eBioMedicine_March_2019.pdf
https://kclpure.kcl.ac.uk/ws/files/108045245/Pellizzari_et_al_Accepted_Ms_eBioMedicine_March_2019.pdf
Autor:
Thayaparan, Thivyan
Malignant pleural mesothelioma (MPM) is an incurable cancer that commonly presents at an advanced stage. Although surgery, chemotherapy and radiotherapy treatment may be used, median survival from diagnosis is less than 12 months. Consequently, new t
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700814
Autor:
Corrigan, Adele
Background: Platinum-based chemotherapy is the main stay of first line treatment for a number of tumour types. However, toxicity is a significant issue, particularly haematological toxicity and sepsis leading to morbidity, hospital admissions and del
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700813
Antibodies used for cancer treatment and immune therapy have, to date, been of the IgG class. Efficacy might be improved by using the IgE class of antibodies as these have higher affinity for their Fc-receptors. IgE has a greater tissue penetration a
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679752
Autor:
Karagiannis, Panagiotis
Antibodies against melanoma antigens have been detected in patients but, despite known regulatory and activatory functions attributed to humoral immunity, the roles of B cells in solid tumours such as melanoma are inadequately understood. Insights in
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762267