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Resolving Issues About Efficacy and Safety of Low-Dose Codeine in Combination Analgesic Drugs: A Systematic Review

Autor: Anja Kos Petrak, Ana Bučan, Ana Soldo, Lidija Bach-Rojecky, Iveta Merćep, Ivan Ćelić

Publikováno v: Pain and Therapy, Vol 9, Iss 1, Pp 171-194 (2020)
Pain and Therapy

Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69101873946f18d348c1ffd9ef8e44a3
https://doi.org/10.1007/s40122-020-00162-8

Treatment of Established Chemotherapy-Induced Peripheral Neuropathy: Basic Science and Animal Models

Autor: Manuel Morales, Nathan P. Staff

Publikováno v: Diagnosis, Management and Emerging Strategies for Chemotherapy-Induced Neuropathy ISBN: 9783030786625

Advancement of effective therapies to treat established CIPN will require a deeper understanding of CIPN pathomechanisms. Simplified models of CIPN have been developed using whole-animal systems, primary cultures, and immortalized cell lines to allow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::827990cca05492ccd3cef71eda3ab784
https://doi.org/10.1007/978-3-030-78663-2_6

Altered Levels of Sphingosine, Sphinganine and Their Ceramides in Atopic Dermatitis Are Related to Skin Barrier Function, Disease Severity and Local Cytokine Milieu

Autor: B. Pavicic, Branka Marinović, Susan M. I. Goorden, Karen J. M. Ghauharali-van der Vlugt, Anamaria Balić, Ivone Jakasa, Ruzica Jurakic Toncic, Sanja Kezic, Kristina Zuzul, Mikela Petkovic, Suzana Ljubojevic Hadzavdic, Femke S. Stet

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 6
International journal of molecular sciences, 21(6):1958. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1958 (2020)

Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83bd2f2db7aaa30cd9a412bfb6ca2b0
http://europepmc.org/articles/PMC7139865

Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P1) Agonists and Future Perspectives

Autor: Alaric J. Dyckman

Publikováno v: Journal of Medicinal Chemistry. 60:5267-5289

The sphingoid base derived class of lipids (sphingolipids) is a family of interconverting molecules that play key roles in numerous structural and signaling processes. The biosynthetic pathway of the sphingolipids affords many opportunities for thera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f35abcdb01b09a1f2d606aee6785d4a
https://doi.org/10.1021/acs.jmedchem.6b01575