Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sphingosine/analogs & derivatives"'
Publikováno v:
Pain and Therapy, Vol 9, Iss 1, Pp 171-194 (2020)
Pain and Therapy
Pain and Therapy
Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69101873946f18d348c1ffd9ef8e44a3
https://doi.org/10.1007/s40122-020-00162-8
https://doi.org/10.1007/s40122-020-00162-8
Autor:
Núria Bielsa, Mireia Casasampere, Jose Luis Abad, Carlos Enrich, Antonio Delgado, Gemma Fabriàs, Jose M. Lizcano, Josefina Casas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7257
instname
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7257
Methuosis is a type of programmed cell death in which the cytoplasm is occupied by fluid-filled vacuoles that originate from macropinosomes (cytoplasmic vacuolation). A few molecules have been reported to behave as methuosis inducers in cancer cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9106da2f20b43c8d0314df44565ad10c
http://hdl.handle.net/10261/275227
http://hdl.handle.net/10261/275227
Autor:
B. Pavicic, Branka Marinović, Susan M. I. Goorden, Karen J. M. Ghauharali-van der Vlugt, Anamaria Balić, Ivone Jakasa, Ruzica Jurakic Toncic, Sanja Kezic, Kristina Zuzul, Mikela Petkovic, Suzana Ljubojevic Hadzavdic, Femke S. Stet
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 6
International journal of molecular sciences, 21(6):1958. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1958 (2020)
Volume 21
Issue 6
International journal of molecular sciences, 21(6):1958. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1958 (2020)
Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83bd2f2db7aaa30cd9a412bfb6ca2b0
http://europepmc.org/articles/PMC7139865
http://europepmc.org/articles/PMC7139865
Autor:
Jean-Christophe Prost, Aurélien Thomas, François R Jornayvaz, Johan Hoffstedt, Richard W. James, Brenda R. Kwak, Mats Eriksson, Miguel Frias, Marie-Claude Brulhart-Meynet, Camilla Pramfalk, Zoltan Pataky, Patrik Löfgren, Sandrine Morel, Jonas Brinck, Miranda Van Eck, Estelle Lauer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 36, No 5 (2016) pp. 817-824
Objective— The dyslipidemia of type 2 diabetes mellitus has multiple etiologies and impairs lipoprotein functionality, thereby increasing risk for cardiovascular disease. High-density lipoproteins (HDLs) have several beneficial effects, notably pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43abd52bbebbea3b963a4954fb3a5776
http://hdl.handle.net/1887/3201770
http://hdl.handle.net/1887/3201770
Autor:
Anne-Claude Gavin, Jeroen Krijgsveld, Mathias J. Gerl, Paul P. Van Veldhoven, Frank Stein, Doris Höglinger, Britta Brügger, Per Haberkant, Carsten Schultz
Publikováno v:
ACS Chemical Biology, Vol. 11, No 1 (2016) pp. 222-230
Sphingolipids are essential structural components of cellular membranes and are crucial regulators of cellular processes. While current high-throughput approaches allow for the systematic mapping of interactions of soluble proteins with their lipid-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4e54e8a92636925caaee3962119304
https://hdl.handle.net/1887/3198348
https://hdl.handle.net/1887/3198348
Autor:
Ursula Felderhoff-Müser, Wiebke Hansen, Ivo Bendix, Josephine Herz, Marco Sifringer, Katharina Lumpe, Karina Kempe, Ralf Herrmann, Martin Hadamitzky, Xinlin Hou, Yohan van de Looij, Meray Serdar, Stéphane Sizonenko, Barbara S. Reinboth, Rolf Heumann
Publikováno v:
Brain, behavior, and immunity, Vol. 52 (2016) pp. 106-19
Cerebral white matter injury is a leading cause of adverse neurodevelopmental outcome in prematurely born infants involving cognitive deficits in later life. Despite increasing knowledge about the pathophysiology of perinatal brain injury, therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107efda10ac14301a02fe7283fc9f3ef
https://www.ncbi.nlm.nih.gov/pubmed/26456693
https://www.ncbi.nlm.nih.gov/pubmed/26456693
Autor:
Boye L. Jensen
Publikováno v:
Jensen, B L 2018, ' Sphingosine-1-phosphate and renal vasoconstriction ', Acta Physiologica
, vol. 222, no. 2, e12971 . https://doi.org/10.1111/apha.12971
, vol. 222, no. 2, e12971 . https://doi.org/10.1111/apha.12971
In the present issue of Acta Physiologica, Guan et al. in their article "Mechanisms of sphingosine-1-phosphate-mediated vasoconstriction of rat afferent arterioles" (1) address the signaling events associated with sphingosine-1-phosphate (S1P)-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80494d3f5778987b8b56faba87b39453
https://doi.org/10.1111/apha.12971
https://doi.org/10.1111/apha.12971
Autor:
Patrice H. Lalive, Claire Bridel
Publikováno v:
Swiss Medical Weekly, Vol. 144 (2014) P. w14012
Relapsing-remitting multiple sclerosis (RRMS) management has dramatically changed over the past decade. New drugs have arrived on the market, allowing for more individualised treatment selection. However, this diversity has increased the complexity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e845fd74c8ee7693b61bc2ac8ade54b
https://pubmed.ncbi.nlm.nih.gov/25247669
https://pubmed.ncbi.nlm.nih.gov/25247669
Publikováno v:
Reggiori, F, Canivenc-Gansel, E & Conzelmann, A 1997, ' Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae ', The EMBO Journal, vol. 16, no. 12, pp. 3506-18 . https://doi.org/10.1093/emboj/16.12.3506
Previous experiments with Saccharomyces cerevisiae had suggested that diacylglycerol-containing glycosylphosphatidylinositols (GPIs) are added to newly synthesized proteins in the endoplasmic reticulum (ER) and that ceramides subsequently are incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662a917ef1f752d15d840f1b4866b98f
https://doi.org/10.1093/emboj/16.12.3506
https://doi.org/10.1093/emboj/16.12.3506
Autor:
Rui-Ping Xiao, Wei Liu, R. John Solaro, Delvac Oceandy, Mark A. Travis, Sukhpal Prehar, Elizabeth J. Cartwright, Min Zi, Andrew Berry, Qing-Jun Meng, Yunbo Ke, Sanjoy K. Chowdhury, Ming Lei, Ludwig Neyses, Hoyee Tsui, Leo A. H. Zeef, Neil A. Hanley, Xin Wang
Publikováno v:
Circulation. Heart failure, 6(4), 833-44. United States (2013).
Liu, W, Zi, M, Tsui, H, Chowdhury, S K, Zeef, L, Meng, Q J, Travis, M, Prehar, S, Berry, A, Hanley, N A, Neyses, L, Xiao, R P, Oceandy, D, Ke, Y, Solaro, R J, Cartwright, E J, Lei, M & Wang, X 2013, ' A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin ', Circulation: Heart Failure, vol. 6, no. 4, pp. 833-844 . https://doi.org/10.1161/CIRCHEARTFAILURE.112.000123, https://doi.org/10.1161/CIRCHEARTFAILURE.112.000123
Liu, W, Zi, M, Tsui, H, Chowdhury, S K, Zeef, L, Meng, Q J, Travis, M, Prehar, S, Berry, A, Hanley, N A, Neyses, L, Xiao, R P, Oceandy, D, Ke, Y, Solaro, R J, Cartwright, E J, Lei, M & Wang, X 2013, ' A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin ', Circulation: Heart Failure, vol. 6, no. 4, pp. 833-844 . https://doi.org/10.1161/CIRCHEARTFAILURE.112.000123, https://doi.org/10.1161/CIRCHEARTFAILURE.112.000123
Background— Hypertension or aortic stenosis causes pressure overload, which evokes hypertrophic myocardial growth. Sustained cardiac hypertrophy eventually progresses to heart failure. Growing evidence indicates that restraining hypertrophy could b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2db5767bf2be90f3aa4fa95797e09c7
http://orbilu.uni.lu/handle/10993/17601
http://orbilu.uni.lu/handle/10993/17601