Expansion of DUB functionality generated by alternative isoforms – USP35, a case study

Autor: Leznicki, Pawel, Natarajan, Jayaprakash, Bader, Gerd, Spevak, Walter, Schlattl, Andreas, Rehman, Syed Arif Abdul, Pathak, Deepika, Weidlich, Simone, Zoephel, Andreas, Bordone, Marie C., Barbosa-Morais, Nuno L., Boehmelt, Guido, Kulathu, Yogesh

Publikováno v: Journal of Cell Science
Leznicki, P, Natarajan, J, Bader, G, Spevak, W, Schlattl, A, Rehman, S A A, Pathak, D, Weidlich, S, Zoephel, A, Bordone, M C, Barbosa-Morais, N L, Boehmelt, G & Kulathu, Y 2018, ' Expansion of DUB functionality generated by alternative isoforms-USP35, a case study ', Journal of Cell Science, vol. 131, no. 10, jcs212753 . https://doi.org/10.1242/jcs.212753

Protein ubiquitylation is a dynamic post-translational modification that can be reversed by deubiquitylating enzymes (DUBs). It is unclear how the small number (∼100) of DUBs present in mammalian cells regulate the thousands of different ubiquityla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b72ae5f32c3e0becf738e5a60a010dc

Heme control region of the catalase T gene of the yeast Saccharomyces cerevisiae.

Autor: Spevak, Walter, Hartig, Andreas, Meindl, Peter, Ruis, Helmut

Publikováno v: Molecular & General Genetics MGG; 1986, Vol. 203 Issue 1, p73-78, 6p

Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase Insight into Domain Movements upon Kinase Activation

Autor: Pautsch, Alexander, Zoephel, Andreas, Ahorn, Horst, Spevak, Walter, Hauptmann, Rudolf, Nar, Herbert

Publikováno v: Structure. (10):955-965

Background: The insulin-like growth-factor-1 (IGF-1) receptor, which is widely expressed in cells that have undergone oncogenic transformation, is emerging as a novel target in cancer therapy. IGF-1-induced receptor activation results in autophosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::010663acb27c5f4dc97730c85be584d8

Isolation of CENIX and CENXII from Saccharomyces cerevisiae.

Autor: Wustinger, Kristina, Spevak, Walter

Publikováno v: Nucleic Acids Research; 7/15/1993, Vol. 21 Issue 14, p3321-3321, 1p