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pro vyhledávání: '"Spermidine transport"'
Akademický článek
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Publikováno v:
Oncotarget
Polyamines spermidine and spermine, and their diamine precursor putrescine, are essential for normal cellular functions in both pro- and eukaryotes. Cellular polyamine levels are regulated by biosynthesis, degradation and transport. Transport of diet
Autor:
Tjerko Kamminga, Nirupama Benis, Vitor Martins dos Santos, Jetta J. E. Bijlsma, Peter J. Schaap
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology, 11
Frontiers in Microbiology 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology, 11
Frontiers in Microbiology 11 (2020)
Mycoplasma hyopneumoniae (M. hyopneumoniae) causes enzootic pneumonia in pigs but it is still largely unknown which host-pathogen interactions enable persistent infection and cause disease. In this study, we analyzed the host and bacterial transcript
Publikováno v:
Molecular Microbiology. 108:350-360
Polyamines are an essential class of metabolites found throughout all kingdoms in life. Borrelia burgdorferi harbors no enzymes to synthesize or degrade polyamines yet does contain a polyamine uptake system, potABCD. In this report, we describe the i
Autor:
Sergey N. Kochetkov, Marine J. Petit, Mervi T. Hyvönen, M. A. Khomutov, Jouko Vepsäläinen, Tuomo A. Keinänen, Leena Alhonen, Janne Weisell, Alex R. Khomutov
Publikováno v:
ACS Chemical Biology. 10:1417-1424
Eukaryotic translation initiation factor 5A (eIF5A) is essential for cell proliferation, becoming functionally active only after post-translational conversion of a specific Lys to hypusine [N(ε)-(4-amino-2-hydroxybutyl)lysine]. Deoxyhypusine synthas
Publikováno v:
European journal of medicinal chemistry. 147
Polyamines play critical roles as regulators of cell growth and differentiation. In contrast with other protozoa, the human parasite Trypanosoma cruzi, the etiological agent of Chagas disease, is auxotrophic for polyamines. Therefore, their intracell
Autor:
Viridiana Olin-Sandoval, Zabdi González-Chávez, Bertha Espinoza, Ricardo Jasso-Chávez, Ingeborg Becker, Emma Saavedra, Rafael Moreno-Sánchez, Ignacio Martínez, Miriam Berzunza-Cruz
Publikováno v:
FEBS Journal. 279:1811-1833
A kinetic model of trypanothione [T(SH)2] metabolism in Trypanosoma cruzi was constructed based on enzyme kinetic parameters determined under near-physiological conditions (including glutathione synthetase), and the enzyme activities, metabolite conc
Publikováno v:
Aquatic Microbial Ecology. 58:311-321
Spermidine, putrescine, and other polyamines are sources of labile carbon and nitrogen in marine environments, yet a thorough analysis of the functional genes encoding their transport and metabolism by marine bacteria has not been conducted. To begin
Autor:
Ece Karatan, C. P. Cartaya‐Marin, Zachary M. Parker, Marcus W. McGinnis, Nicholas Emmanuel Walter, Alex C. Rutkovsky
Publikováno v:
FEMS Microbiology Letters. 299:166-174
Vibrio cholerae, the causative agent of the devastating diarrheal disease cholera, can form biofilms on diverse biotic and abiotic surfaces. Biofilm formation is important for the survival of this organism both in its natural environment and in the h
Autor:
Sandeep J. Joseph, Maira Goytia, Vijaya Dhulipala, Timothy D. Read, Leo Hawel, William M. Shafer
During infection, Neisseria gonorrhoeae, the causative agent of the sexually transmitted disease gonorrhea, comes into contact with numerous host compounds including polyamines (e.g. spermine and spermidine). Here, we show that spermine and spermidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a34b4fcbaa1626f7b7fc7ee9bf00a11
https://europepmc.org/articles/PMC4565982/
https://europepmc.org/articles/PMC4565982/