Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Spermatozoa/metabolism"'
Autor:
Ulrike Jakop, Karin Müller, Peter Müller, Stefanie Neuhauser, Isabel Callealta Rodríguez, Sonja Grunewald, Jurgen Schiller, Kathrin M. Engel
Publikováno v:
PloS one. 17(3)
On their way to the oocyte, sperm cells are subjected to oxidative stress, which may trigger the oxidation of phospholipids (PL). Applying MALDI-TOF MS, HPTLC and ESI-IT MS, we comparatively analyzed the PL compositions of semen and blood of species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1677e705568bd8cf64522a8b7de53e
https://pubmed.ncbi.nlm.nih.gov/35259184
https://pubmed.ncbi.nlm.nih.gov/35259184
Autor:
Shiraishi, K., Shindo, A., Harada, A., Kurumizaka, H., Kimura, Hiroshi, Ohkawa, Y., Matsuyama, H.
Publikováno v:
Andrology. 6:158-165
Histone H3.5 (H3.5) is a newly identified histone variant highly expressed in the human testis. We have reported the crystal structure, instability of the H3.5 nucleosome and accumulation around transcription start sites, mainly in primary spermatocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856072c53b37307b98599b5a05a8a68a
https://doi.org/10.1111/andr.12438
https://doi.org/10.1111/andr.12438
Publikováno v:
The Lancet Diabetes & Endocrinology. 5:554-564
Summary An accurate medical history and directed physical examination are essential in diagnosis of male infertility. We review the hormonal assessments and specific genetic analyses that are useful additional tests, and detail other evidence-based e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac04fa8f97954f6715400ce26ccd320b
https://doi.org/10.1016/s2213-8587(16)30043-2
https://doi.org/10.1016/s2213-8587(16)30043-2
Autor:
Lawrence Salkoff, Alice Butler, Pascale Lybaert, Yanyan Geng, Karl Kl Magleby, Peng Yuan, Celia Cm Santi, Victor Dzikunu, Juan J. Ferreira
Publikováno v:
The Journal of biological chemistry, 292 (21
To fertilize an oocyte, sperm must first undergo capacitation in which the sperm plasma membrane becomes hyperpolarized via activation of potassium (K(+)) channels and resultant K(+) efflux. Sperm-specific SLO3 K(+) channels are responsible for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd682bed87048357fbcf878e5762e60
https://doi.org/10.1074/jbc.m117.776013
https://doi.org/10.1074/jbc.m117.776013
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5518 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences
Volume 20
Issue 21
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences
Volume 20
Issue 21
The unfolded protein response (UPR) is involved in protein quality control and is activated in response to several stressors. Although in testis the UPR mechanisms are well described, their presence in spermatozoa is contentious. We aimed to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79a42b5381e99e3e1b0460fd557cbbe
https://www.mdpi.com/1422-0067/20/21/5518
https://www.mdpi.com/1422-0067/20/21/5518
Publikováno v:
Illum, L R, Bak, S T, Lund, S & Nielsen, A L 2018, ' DNA methylation in epigenetic inheritance of metabolic diseases through the male germ line ', Journal of Molecular Endocrinology, vol. 60, no. 2, pp. R39-R56 . https://doi.org/10.1530/JME-17-0189
The global rise in metabolic diseases can be attributed to a complex interplay between biology, behavior and environmental factors. This article reviews the current literature concerning DNA methylation-based epigenetic inheritance (intergenerational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57692fdc06a9815722c1f934f071300b
https://pure.au.dk/portal/da/publications/dna-methylation-in-epigenetic-inheritance-of-metabolic-diseases-through-the-male-germ-line(feee6552-5fa4-4e05-aeb4-33b7b20c75e3).html
https://pure.au.dk/portal/da/publications/dna-methylation-in-epigenetic-inheritance-of-metabolic-diseases-through-the-male-germ-line(feee6552-5fa4-4e05-aeb4-33b7b20c75e3).html
Publikováno v:
Dardmeh, F, Alipour, H, Nielsen, H I, Rasmussen, S & Gazerani, P 2017, ' Effects of Chronic Musculoskeletal Pain on Fertility Potential in Lean and Overweight Male Patients ', Pain Research & Management, vol. 2017, 4628627 . https://doi.org/10.1155/2017/4628627
Pain Research & Management
Pain Research and Management, Vol 2017 (2017)
Pain Research & Management
Pain Research and Management, Vol 2017 (2017)
Both chronic pain and obesity are known to affect reproductive hormone profiles in male patients. However, the effect of these conditions, alone or in combination, on male fertility potential has received less attention. 20 chronic musculoskeletal pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c63b54e4d418c7869d4b2fadf5f1c04
https://vbn.aau.dk/da/publications/d725eb85-aa08-44dd-8759-2c0309c6d059
https://vbn.aau.dk/da/publications/d725eb85-aa08-44dd-8759-2c0309c6d059
Publikováno v:
Freeman, P, Macfarlane, C, Collier, P, Jeffreys, A J & Badge, R M 2011, ' L1 Hybridization Enrichment : A Method for Directly Accessing De Novo L1 Insertions in the Human Germline ', Human Mutation, vol. 32, no. 8, pp. 978-988 . https://doi.org/10.1002/humu.21533
Human Mutation
Human Mutation
Long interspersed nuclear element 1 (L1) retrotransposons are the only autonomously mobile human transposable elements. L1 retrotransposition has shaped our genome via insertional mutagenesis, sequence transduction, pseudogene formation, and ectopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61bc1d8443bf528447019075b336a21
https://doi.org/10.1002/humu.21533
https://doi.org/10.1002/humu.21533
Publikováno v:
Reproductive Toxicology, Vol. 28, No 4 (2009) pp. 536-541
Some steps of the assisted reproduction techniques, such as superovulation, may interfere with imprinting reprogramming. In the present study, superovulation was induced in the mouse and its possible effects on the differentially methylated domains o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfbc278d5b9e79eba264b5c3a6cf63c
https://doi.org/10.1016/j.reprotox.2009.06.009
https://doi.org/10.1016/j.reprotox.2009.06.009
Autor:
Yannick Romero, Henrik Kaessmann, Maria Warnefors, Christelle Borel, Adem Bilican, Lee B. Smith, Céline Zimmermann, Serge Nef, Noora Kotaja
Publikováno v:
PLoS ONE
PLOS ONE, Vol. 9, No 9 (2014) P. e107023
Zimmermann, C, Romero, Y, Warnefors, M, Bilican, A, Borel, C, Smith, L B, Kotaja, N, Kaessmann, H & Nef, S 2014, ' Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility ', PLoS ONE, vol. 9, no. 9, e107023, pp. e107023 . https://doi.org/10.1371/journal.pone.0107023
PLoS ONE, Vol 9, Iss 9, p e107023 (2014)
PLoS One, vol. 9, no. 9, pp. e107023
PLOS ONE, Vol. 9, No 9 (2014) P. e107023
Zimmermann, C, Romero, Y, Warnefors, M, Bilican, A, Borel, C, Smith, L B, Kotaja, N, Kaessmann, H & Nef, S 2014, ' Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility ', PLoS ONE, vol. 9, no. 9, e107023, pp. e107023 . https://doi.org/10.1371/journal.pone.0107023
PLoS ONE, Vol 9, Iss 9, p e107023 (2014)
PLoS One, vol. 9, no. 9, pp. e107023
Small non-coding RNAs act as critical regulators of gene expression and are essential for male germ cell development and spermatogenesis. Previously, we showed that germ cell-specific inactivation of Dicer1, an endonuclease essential for the biogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf63595320f5e9870ec27857ad48e96
https://pubmed.ncbi.nlm.nih.gov/25244517
https://pubmed.ncbi.nlm.nih.gov/25244517