Výsledky vyhledávání - "Spermatogenesis/genetics"

The molecular evolution of spermatogenesis across mammals

Publikováno v: Murat, F, Mbengue, N, Winge, S, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Riera Belles, M, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature .
Murat, F, Mbengue, N, Winge, S B, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Belles, M R, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature, vol. 613, pp. 308–316 . https://doi.org/10.1038/s41586-022-05547-7
Nature, 613. Nature Research
Nature

The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological and molecular level in mammals1-6, probably owing to the evolutionary pressure on males to be reproductively successful7. However, the molecular evoluti

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Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility

Autor: Cerván-Martín, Miriam, Tüttelmann, Frank, Lopes, Alexandra M., Bossini-Castillo, Lara, Rivera-Egea, Rocío, Garrido, Nicolás, Lujan, Saturnino, Romeu, Gema, Santos-Ribeiro, Samuel, Castilla, José A., Gonzalvo, M. Carmen, Clavero, Ana, Maldonado, Vicente, Vicente, F.Javier, González-Muñoz, Sara, Guzmán-Jiménez, Andrea, Burgos, Miguel, Jiménez, Rafael, Pacheco, Alberto, González, Cristina, Gómez, Susana, Amorós, David, Aguilar, Jesus, Quintana, Fernando, Calhaz-Jorge, Carlos, Aguiar, Ana, Nunes, Joaquim, Sousa, Sandra, Pereira, Isabel, Pinto, Maria Graça, Correia, Sónia, Sánchez-Curbelo, Josvany, López-Rodrigo, Olga, Martín, Javier, Pereira-Caetano, Iris, Marques, Patricia I., Carvalho, Filipa, Barros, Alberto, Gromoll, Jörg, Bassas, Lluís, Seixas, Susana, Gonçalves, João, Larriba, Sara, Kliesch, Sabine, Palomino-Morales, Rogelio J., Carmona, F. David, Universitat Autònoma de Barcelona

Acknowledgements We thank the National DNA Bank Carlos III (University of Salamanca, Spain) for supplying part of the control DNA samples from Spain and all the participants for their essential collaboration. This work was supported by the Spanish Mi

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https://hdl.handle.net/10481/78210

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Common genetic variation in KATNAL1 non-coding regions is involved in the susceptibility to severe phenotypes of male infertility

Publikováno v: Andrology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ANDROLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

© 2022 The Authors. Andrology published by Wiley Periodicals LLC on behalf of American Society of Andrology and European Academy of Andrology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License,

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Wiley Online Library

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The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility

Autor: Pei Hsuan Wu, Yu Fu, Phillip D. Zamore, Katharine Cecchini, Cansu Colpan, Amena Arif, Tianxiong Yu, Deniz M. Ozata, Zhiping Weng, Ildar Gainetdinov

Publikováno v: Nature genetics, Vol. 52, No 7 (2020) pp. 728-739

Pachytene PIWI-interacting RNAs (piRNAs), which comprise >80% of small RNAs in the adult mouse testis, have been proposed to bind and regulate target RNAs like microRNAs, cleave targets like short interfering RNAs or lack biological function altogeth

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https://doi.org/10.1038/s41588-020-0657-7

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Research Resource: The Dynamic Transcriptional Profile of Sertoli Cells During the Progression of Spermatogenesis

Autor: Isabelle Stévant, Béatrice Conne, Pierre Calvel, Bernard Jégou, Céline Zimmermann, Henrik Kaessmann, Frédéric Chalmel, Jean-Luc Pitetti, Christelle Borel, Serge Nef

Publikováno v: Molecular Endocrinology, Vol. 29, No 4 (2015) pp. 627-642
Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2015, 29 (4), pp.627--642. ⟨10.1210/me.2014-1356⟩
Molecular Endocrinology-Baltimore-, 2015, 29 (4), pp.627--642. ⟨10.1210/me.2014-1356⟩
Molecular endocrinology (Baltimore Md.)

Sertoli cells (SCs), the only somatic cells within seminiferous tubules, associate intimately with developing germ cells. They not only provide physical and nutritional support but also secrete factors essential to the complex developmental processes

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https://doi.org/10.1210/me.2014-1356

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Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility

Autor: Yannick Romero, Henrik Kaessmann, Maria Warnefors, Christelle Borel, Adem Bilican, Lee B. Smith, Céline Zimmermann, Serge Nef, Noora Kotaja

Publikováno v: PLoS ONE
PLOS ONE, Vol. 9, No 9 (2014) P. e107023
Zimmermann, C, Romero, Y, Warnefors, M, Bilican, A, Borel, C, Smith, L B, Kotaja, N, Kaessmann, H & Nef, S 2014, ' Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility ', PLoS ONE, vol. 9, no. 9, e107023, pp. e107023 . https://doi.org/10.1371/journal.pone.0107023
PLoS ONE, Vol 9, Iss 9, p e107023 (2014)
PLoS One, vol. 9, no. 9, pp. e107023

Small non-coding RNAs act as critical regulators of gene expression and are essential for male germ cell development and spermatogenesis. Previously, we showed that germ cell-specific inactivation of Dicer1, an endonuclease essential for the biogenes

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https://pubmed.ncbi.nlm.nih.gov/25244517

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Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects

Autor: Manuela Weier, Serge Nef, Jean-Dominique Vassalli, Noora Kotaja, François P. Pralong, Henrik Kaessmann, Béatrice Conne, Bernard de Massy, Marilena D. Papaioannou, Corinne Grey, Oliver Meikar, Yannick Romero

Publikováno v: PLoS One, vol. 6, no. 10, pp. e25241
PLOS ONE, Vol. 6, No 10 (2011) P. e25241
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (10), pp.E25241. ⟨10.1371/journal.pone.0025241⟩
PLoS ONE, Vol 6, Iss 10, p e25241 (2011)
PloS one

International audience; Background: Spermatogenesis is a complex biological process that requires a highly specialized control of gene expression. In the past decade, small non-coding RNAs have emerged as critical regulators of gene expression both a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca9f059c9178a618714c1647a7ceb37
https://serval.unil.ch/notice/serval:BIB_C14CDFC8DC83

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